Chlortalidone tablets
Hylaton
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 28 mars 2023
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Chlortalidone is a 'water tablet' (a diuretic).
It is best taken in the morning, with breakfast.
Any side-effects are usually mild, but may include feeling sick (nausea) or dizziness.
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About chlortalidone
Typ av medicin | A thiazide-related diuretic |
Används för | High blood pressure; fluid retention; heart failure; diabetes insipidus |
Även kallad | Chlorthalidone (in US); Hylaton® Combination brands are: Tenoret® (chlortalidone with atenolol); Tenoretic® (chlortalidone with atenolol); |
Tillgänglig som | Tabletter |
Chlortalidone belongs to a group of medicines called thiazide-related diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water tablets'. Diuretics are a common treatment for high blood pressure (hypertension). They are also used to clear excess fluid in some liver and kidney conditions where the body retains more fluid than it needs. Chlortalidone is also useful in people who have heart failure. Heart failure is a condition where the heart does not function as well as it should.
Diuretics like chlortalidone work by interfering with the movement of salt and water across certain cells in your kidneys. The effect of this is to make your kidneys pass out more urine. The removal of fluid reduces your blood pressure and helps reduce the work your heart has to do. Chlortalidone tends to have only a weak action on the kidneys, so it is unlikely you will notice a great increase in urine.
Chlortalidone may also be given alongside other medicines used to treat fluid retention and/or hypertension. When it is used like this, you may be prescribed a combination tablet. Combination tablets help to reduce the total number of tablets you need to take each day.
Chlortalidone tablets may also be of benefit to people with diabetes insipidus. This is a condition where a person produces large amounts of dilute urine and is constantly thirsty. How chlortalidone works in diabetes insipidus is not fully understood.
Before taking chlortalidone
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking chlortalidone it is important that your doctor knows:
Om du är gravid eller ammar.
If you have kidney or liver problems.
If you have gout, diabetes, or an inflammatory condition called lupus or SLE (systemic lupus erythematosus). These conditions may be made worse by diuretics.
If you have been told by a doctor that you have low sodium or potassium levels in your blood, or high calcium levels in your blood.
If you have a problem with your adrenal glands, called Addisons sjukdom.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take chlortalidone
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the tablets and a full list of side-effects which you may experience from taking them.
Take chlortalidone exactly as your doctor tells you to. The usual dose is ½-1 tablet daily (25-50 mg), although your dose may be different to this. Your doctor is likely to recommend that you take your dose in the morning. This is so it works during the day and your sleep is not disturbed by needing to get up to make extra trips to the toilet during the night.
Although you can take the tablets before or after food, you are recommended to take them after a meal (usually breakfast). This is because the food in your stomach will help to reduce the side-effect of stomach upset.
If you forget to take a dose, take it as soon as you remember. However, if it is after 6 pm in the evening, you should skip the forgotten dose and continue as usual the next day. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Tillbaka till innehållDiuretics like chlortalidone help you to lose water. Occasionally you may lose too much and become dehydrated. Let your doctor know if you feel constantly thirsty, your mouth is dry, or your skin looks and feels dry.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by chlortalidone and your doctor may want you to have a blood test from time to time to check for this.
If you have been prescribed chlortalidone for high blood pressure, your treatment is likely to be long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems. It is important that you continue to take chlortalidone regularly to help reduce the risk of this.
You may also be given some lifestyle or dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet and taking some regular exercise. Following this advice will help to reduce the risk of damage to your heart and blood vessels.
Drinking alcohol while you are on chlortalidone may make you feel dizzy. Ask for your doctor's advice about whether you should avoid alcohol.
If you buy any medicines, check with a pharmacist that they are suitable to take alongside chlortalidone.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
If you have diabetes (diabetes mellitus), chlortalidone may affect your blood sugar (glucose) levels. Test your blood or urine regularly and speak with your doctor if you notice any significant changes.
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Can chlortalidone cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with chlortalidone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common chlortalidone side-effects | Vad kan jag göra om jag upplever detta? |
Loss of appetite, mild gastrointestinal effects such as feeling sick (nausea) or stomach upset | This is usually mild, but it may help to take the tablets after food |
Feeling dizzy, particularly when you stand up (due to low blood pressure) | Getting up more slowly should help. Do not drive and do not use tools or machines until you feel better |
Impotence, itchy skin rash | Om någon av dessa blir besvärlig, tala med din läkare |
Changes in some blood tests | Your doctor will monitor for this |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store chlortalidone
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Tenoret® 50 mg/12.5 mg film coated tablets (atenolol with chlortalidone); AstraZeneca UK Ltd, The electronic Medicines Compendium. Dated July 2021.
- Manufacturer's PIL, Hylaton® 12.5 mg tablets; Morningside Healthcare Ltd, The electronic Medicines Compendium. Dated September 2020.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Nästa granskning: 27 sept 2027
28 mars 2023 | Senaste versionen

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