Clopidogrel för att förebygga blodproppar
Plavix
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 25 apr 2024
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For people who have heart or blood vessel disease, taking clopidogrel each day can reduce the risk of heart attack and stroke.
Take one 75 mg tablet each day.
The most common side-effect is bleeding. If you cut yourself, it might take slightly longer than normal to stop the bleeding.
Överblick
Clopidogrel is an antiplatelet medicine that helps prevent blood clots.
It reduces the stickiness of platelets to lower the risk of heart attack or stroke.
Take one tablet daily at a time you can easily remember, with or without food.
Avoid medicines containing aspirin or anti-inflammatory painkillers unless advised by your doctor.
If you have an operation or dental treatment, tell the person treating you that you take clopidogrel.
Contact your doctor if you experience unusual or unexplained bleeding.
About clopidogrel
Typ av medicin | An antiplatelet medicine |
Används för | To prevent clots from forming in blood vessels |
Även kallad | Plavix® |
Tillgänglig som | Tabletter |
In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. A thrombus can block a blood vessel, and this is often the cause of a stroke eller hjärtattack. This is more likely to happen if the walls of your arteries have areas which have become thickened with fat deposits, or if you have a fast irregular heartbeat.
If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem. If you have been prescribed clopidogrel because you have ACS, it may mean that you have had a heart attack, or that you have angina pain that is not well controlled.
Clopidogrel reduces the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of an artery and forming a thrombus. This reduces the risk of you having a heart attack or stroke.
Before taking clopidogrel
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking clopidogrel it is important that your doctor knows:
Om du är gravid eller ammar.
If you have a condition which causes bleeding (such as a stomach ulcer), or if you have recently had surgery or an injury.
If you have any problems with the way your liver works or with the way your kidneys work.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take clopidogrel
Before you start taking the tablets, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about clopidogrel and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. It is likely you will be prescribed one tablet of 75 mg clopidogrel to take each day. Although there are two strengths of clopidogrel tablets available (75 mg and 300 mg), the higher-strength tablet is only given as a first dose in some conditions.
You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.
If you forget to take a dose, take it as soon as you remember. If you do not remember until more than 12 hours after the time the dose should have been taken then skip the forgotten dose. Do not take two doses at the same time to make up for a missed dose.
Få ut det mesta av din behandling
Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress.
Before buying or taking any 'over-the-counter' medicines, check with your pharmacist whether the medicine is safe for you to take. You should not take any medicines which contain aspirin or any anti-inflammatory painkiller such as ibuprofen, unless your doctor has told you otherwise. This is because these medicines can increase the risk of bleeding when they are taken with clopidogrel. Many cold and flu remedies contain aspirin or ibuprofen.
If you are due to have an operation or dental treatment, tell the person carrying out the treatment that you are taking clopidogrel. This is because it is possible that any bleeding may take longer than normal to stop.
While you are on clopidogrel, it might take longer than normal to stop bleeding if you cut yourself. If this happens and you find it difficult to stop the bleeding, contact your doctor. Also, if you notice any unusual or unexplained bleeding, speak with your doctor about this too.
Can clopidogrel cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with clopidogrel. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common clopidogrel side-effects (these affect less than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Bleeding, nosebleeds, bruising, bleeding under the skin (blood blisters) | Because of the way clopidogrel works, any bleeding may take longer than normal to stop. If this becomes troublesome, let your doctor know |
Indigestion, tummy (abdominal) pain, diarrhoea | Håll dig till enkla måltider - undvik rik eller kryddstark mat |
Important: clopidogrel can occasionally cause unwanted effects which are more serious than the ones listed above. Although these occur only rarely, you should contact your doctor for advice if you feel generally unwell or if you experience any other symptoms which you think may be due to the tablets.
How to store clopidogrel
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
Can I take other medicines, including over-the-counter ones, with clopidogrel?
You should check with your pharmacist before taking any 'over-the-counter' medicines. It's particularly important to avoid medicines containing aspirin or anti-inflammatory painkillers like ibuprofen, as these can increase the risk of bleeding when taken with clopidogrel, unless specifically advised by your doctor. Many cold and flu remedies may contain these ingredients.
What should I do if I need surgery or dental treatment while taking clopidogrel?
If you are scheduled for any operation or dental treatment, you must inform the healthcare professional carrying out the procedure that you are taking clopidogrel. This is important because clopidogrel can cause any bleeding to take longer than usual to stop.
What are the common side effects of clopidogrel?
Common side effects, affecting less than 1 in 10 people, include bleeding, nosebleeds, bruising, and bleeding under the skin (blood blisters). Due to how clopidogrel works, any bleeding might take longer to stop. Other common side effects are indigestion, tummy pain, and diarrhoea. These often improve as your body adjusts to the medicine.
Should I be concerned about any rare but serious side effects?
Yes, clopidogrel can, on rare occasions, cause more serious unwanted effects. If you feel generally unwell or experience any other symptoms you think might be due to the tablets, you should contact your doctor for advice.
What should I do if I cut myself or notice unusual bleeding while on clopidogrel?
While taking clopidogrel, it might take longer than normal for bleeding to stop if you cut yourself. If you find it difficult to stop the bleeding, you should contact your doctor. Similarly, if you notice any unusual or unexplained bleeding, speak with your doctor about it.
Vidare läsning och referenser
- Manufacturer's PIL, Plavix® 75 mg tablets; Sanofi, The electronic Medicines Compendium. Dated December 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 21 Feb 2027
25 apr 2024 | Senaste versionen

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