Phytomenadione injection
Konakion MM
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 23 Dec 2024
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Phytomenadione is a man-made form of vitamin K.
It is used to treat people who are at risk of bleeding because of taking anticoagulant medicines.
At a glance
Phytomenadione is a form of vitamin K used to prevent or reverse bleeding.
It is often used to counteract the effects of anticoagulant medicines like warfarin.
It can be given by injection or by mouth.
Doctors or nurses usually give phytomenadione.
It is also given to newborn babies to prevent bleeding problems.
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About phytomenadione
Typ av medicin | A form of vitamin K; an antihaemorrhagic |
Används för | To prevent bleeding caused by anticoagulant medicines; to reverse the anticoagulant effects of warfarin before an operation |
Även kallad | Phytonadione (in US); Konakion® MM |
Tillgänglig som | Injection for intravenous or oral use |
Vitamin K is a fat-soluble vitamin which is essential for blood clotting. It also plays a role in bone health.
People who take anticoagulant medicines such as warfarin are at risk of bleeding. Regular blood tests are needed to check on how quickly the blood clots. The aim is to get the dose of warfarin just right so that the blood does not clot as easily as normal, but not so much as to cause bleeding problems. If the dose of the anticoagulant is too high then bleeding can become a problem. Phytomenadione is given as an antidote to bleeding caused by anticoagulant medicines such as warfarin. It is likely to be given by injection in hospital.
If a person who is taking a medicine like warfarin needs to have an operation at short notice then the effects of the anticoagulant medicine will need to be reversed before the surgery takes place. Vitamin K is given to reduce the risk of bleeding during the surgery.
Vitamin K is given to newborn babies soon after birth to prevent possible bleeding problems. It is usually given as an injection but the liquid medicine can also be swallowed. If you have been asked to give the medicine by mouth, your doctor or midwife will give you instructions on how much to give and when.
Before having phytomenadione
Tillbaka till innehållTo make sure that this is the right treatment for you it is important that your doctor knows:
Om du är gravid eller ammar.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How phytomenadione is given
Tillbaka till innehållPhytomenadione injection will be given by a doctor or nurse. Ask to read the manufacturer's printed information leaflet from inside the pack - it will give you more information about treatment with phytomenadione.
You may be given the injection to swallow by mouth. This is often the case for people who are taking phytomenadione before surgery, or who have abnormal blood results but who do not have any symptoms of bleeding.
If you have been asked to give phytomenadione to your newborn baby by mouth, follow the midwife's or doctor's instructions carefully. Read the printed manufacturer's instructions on how to use the ampoule and dropper. A dose is usually needed at 1 week old and then at 1 month old.
Få ut det mesta av din behandling
Tillbaka till innehållIf you have any questions about your treatment, please ask your doctor or nurse for further advice.
After you have left hospital, remember to keep your regular clinic appointments so that your progress can be monitored.
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Can phytomenadione cause problems?
Tillbaka till innehållVery occasionally there have been reports of irritation or allergic-type reactions, but otherwise the medicine is unlikely to cause side-effects. If you experience any other symptoms which you think could be due to phytomenadione, please speak with your doctor or pharmacist for further advice.
How to store phytomenadione
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
If you buy any medicines 'over the counter', check with a pharmacist that they are safe to take with your prescribed medicines.
If you are due to have an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking.
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
If you have any questions about this medicine, ask your doctor or pharmacist.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
What is phytomenadione typically used for in hospitals?
Phytomenadione is used in hospitals primarily as an antidote to bleeding caused by anticoagulant medicines like warfarin. This could be if the anticoagulant dose is too high and causes bleeding problems, or if a person on warfarin needs an urgent operation and their blood clotting needs to be reversed quickly to reduce the risk of bleeding during surgery.
Why is phytomenadione given to newborn babies?
Phytomenadione is given to newborn babies shortly after birth to prevent possible bleeding problems. It is typically administered as an injection, though it can also be given orally through liquid medicine.
Can I take other medicines alongside phytomenadione?
Before you receive phytomenadione, it's important that your doctor knows about all other medicines you are taking. This includes any medicines bought without a prescription, as well as herbal and complementary medicines. This helps ensure that phytomenadione is the right treatment for you and avoids potential interactions.
How is phytomenadione usually administered?
Phytomenadione is most commonly given as an injection by a doctor or nurse. However, in some cases, particularly for those preparing for surgery or with abnormal blood results without bleeding symptoms, the injection liquid may be given to swallow by mouth. For newborn babies, it can be given as an injection or as swallowed liquid medicine.
Are there any serious side effects from taking phytomenadione?
While generally unlikely to cause side-effects, very occasionally, individuals have reported irritation or allergic-type reactions. If you experience any symptoms that you believe might be related to phytomenadione, you should speak with your doctor or pharmacist for advice.
Vidare läsning och referenser
- Manufacturer's PIL, Konakion® MM 10 mg/ml injection; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated October 2023.
- Manufacturer's PIL, Konakion MM Paediatric 2 mg/0.2 ml; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated October 2023.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 23 Dec 2027
23 Dec 2024 | Senaste versionen

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