Colestyramine sachets
Questran
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 30 Aug 2023
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Mix the powder from each sachet with at least 150 ml of liquid. You can mix it with water, skimmed milk, thin soup, fruit juice or puréed fruit.
Avoid taking any other medicines at the same time as colestyramine. Either take your other medicines one hour before colestyramine, or wait until 4-6 hours afterwards.
The most common side-effect is constipation.
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About colestyramine
Typ av medicin | A bile acid sequestrant (binder) |
Används för | Lowering cholesterol; itching caused by damage to the bile ducts; diarrhoea |
Även kallad | Cholestyramine (in US); Questran®; Questran® Light |
Tillgänglig som | Sachets of powder |
Colestyramine is a powder which works in the body as a bile acid sequestrant. This means that it binds to bile acids in your digestive system. It prevents bile acids from being reabsorbed (recycled) into your body, and this action can be useful in a number of different conditions.
You may be prescribed colestyramine sachets to help lower the amount of kolesterol in your blood, or to reduce itching caused by a problem in your bile ducts (such as primary biliary cirrhosis), or to help reduce diarré caused by certain medical conditions or treatments.
When it is prescribed to lower cholesterol, by preventing the bile acids from being reabsorbed, your liver has to make more bile acids, which it does by using cholesterol from your blood. This lowers the amount of cholesterol in your blood and reduces your risk of blood vessel disease.
When colestyramine is prescribed for itching or diarrhoea, it helps to control your symptoms by reducing the amount of bile acids in your blood.
Before taking colestyramine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colestyramine it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
Om du tar andra läkemedel, inklusive de som kan köpas utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take colestyramine
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about colestyramine and will provide you with a full list of the side-effects which you may experience from taking it.
Take the sachets exactly as your doctor tells you to. It is usual to be prescribed one or two sachets to take each day to begin with. Depending upon your symptoms, your doctor may slowly increase the number of sachets until you are taking 3-6 sachets daily. The maximum dose is nine sachets daily. You may need to take all your sachets as one dose or as separate doses up to four times a day.
The powder from each sachet should be added to at least 150 ml of water. Allow the mixture to stand for 1-2 minutes, and then stir it well. If you prefer, you can also mix colestyramine with skimmed milk, soup, fruit juice or fruit smoothies. Do not take the powder without mixing it into some liquid first.
If you forget to take a dose, take it as soon as you remember. Try to take the correct number of sachets each day.
Få ut det mesta av din behandling
Tillbaka till innehållTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.
Avoid taking any other medicines at the same time as you take colestyramine because it can stop the other medicines from being absorbed by your body. Either take your other medicines at least an hour before you take colestyramine, or wait until 4-6 hours after taking colestyramine before you take the other medicines. If you have any problems planning when to take your medicines, speak with your doctor or pharmacist for advice.
Treatment with colestyramine is often long-term. Continue to take it unless you are advised otherwise.
Taking colestyramine over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.
If you have been prescribed colestyramine to lower cholesterol, your doctor may give you advice about lifestyle changes that could help you get the most out of your treatment. This may include reducing the amount of salt in your diet, stopping smoking, losing weight, reducing the amount of alcohol you drink, and taking regular exercise. Following this advice will help you to reduce your risk of developing heart and blood vessel disease in the future.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
If you buy any medicines 'over-the-counter', check with a pharmacist that they are suitable for you to take.
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Can colestyramine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestyramine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common colestyramine side-effects | Vad kan jag göra om jag upplever detta? |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day. If it becomes troublesome, speak with your doctor |
Upset stomach | Håll dig till enkla måltider - undvik rik eller kryddstark mat |
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
How to store colestyramine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Questran® Powder for Oral Suspension 4 g; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2021.
- Manufacturer's PIL, Questran® Light, Powder for Oral Suspension 4 g; Neon Healthcare Ltd, The electronic Medicines Compendium. Dated December 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 29 Aug 2026
30 Aug 2023 | Senaste versionen

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