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Dronedaron-tabletter

Multaq

Dronedarone is given to maintain a regular heart rhythm after cardioversion. Treatment with it will be started by a heart specialist.

The usual dose is one tablet twice daily. Take the tablets during breakfast and your evening meal.

Dronedarone can cause a number of side-effects which your doctor will discuss with you before you start treatment. If you develop any signs of liver damage or heart failure, you must let your doctor know straightaway.

Överblick

  • Dronedarone is a medicine for people with an irregular heart rhythm called atrial fibrillation (AF).

  • It helps maintain a regular heart rhythm after a treatment called cardioversion.

  • Take tablets twice daily with food, usually breakfast and the evening meal.

  • Do not drink grapefruit juice and tell your doctor or dentist about all medicines you are taking.

  • See your doctor for regular check-ups and blood tests while taking this medicine.

  • Speak to your doctor immediately if you notice signs of heart failure or liver damage.

About dronedarone

Typ av medicin

An anti-arrhythmic medicine

Används för

Atrial fibrillation (irregular heartbeats)

Även kallad

Multaq®

Tillgänglig som

Tabletter

Dronedarone is prescribed for people with an irregular heart rhythm called atrial fibrillation (AF). AF happens when the normal controlling timer in the heart (that causes it to beat regularly) is overridden. This causes parts of the heart to beat very rapidly, and other parts to beat haphazardly. A treatment called cardioversion is a way of converting the irregular rhythm back to a normal regular rhythm. Dronedarone is prescribed to maintain the regular heart rhythm after cardioversion. It will be prescribed by a specialist doctor.

Before taking dronedarone

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dronedarone it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have any problems with the way your liver works or with the way your kidneys work.

  • If you have any other heart conditions.

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have taken a medicine called amiodarone and had problems with your breathing as a result. Also let your doctor know if you are taking anticoagulant medicines like apixaban or rivaroxaban.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

How to take dronedarone tablets

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about dronedarone and a full list of side-effects which you may experience from taking it.

  • Take dronedarone exactly as your doctor tells you to. It is usually taken twice daily, the first dose in the morning during breakfast and the second dose during the evening meal. Swallow the tablets with a drink of water.

  • If you forget to take a dose, take it (with something to eat) as soon as you remember. If when you remember, it is nearly time for your next dose then leave out the missed dose and take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • Try to keep your regular appointments with your doctor. This is so your doctor can check your heart rhythm and monitor your progress. Your doctor will also want to do some blood tests while you are on dronedarone to check your liver function.

  • Do not drink grapefruit juice while you are on dronedarone. This is because a chemical in grapefruit juice increases the amount of dronedarone in your bloodstream and increases the risk of side-effects.

  • Treatment with dronedarone can be long-term. You should continue to take the tablets unless you are advised otherwise.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking dronedarone.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with dronedarone. This is because a number of medicines can interfere with dronedarone.

Can dronedarone tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with dronedarone. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common dronedarone side-effects (these affect fewer than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Feeling sick (nausea), indigestion, tummy (abdominal) pain

Eat simple meals - avoid rich or spicy food

Diarré

Drink plenty of water to replace lost fluids

Känner dig trött

Do not drive and do not use tools or machines until you feel more awake

Viktigt: dronedarone is associated with a number of serious unwanted effects affecting the heart and liver. You must let your doctor know omedelbart if you notice any of the following:

  • An increase in weight, trouble breathing or feeling short of breath, swollen feet or legs. These could be signs of heart failure.

  • Extreme tiredness, abdominal pain, high temperature, sickness, itchy skin, dark urine or yellowing of your skin or of the whites of your eyes (jaundice). These could be signs of damage to your liver.

If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist.

How to store dronedarone

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

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Vanliga frågor

What is atrial fibrillation and how does cardioversion relate to it?

Atrial fibrillation (AF) is an irregular heart rhythm where the heart's natural timer is overridden, causing parts of the heart to beat very rapidly and haphazardly. Cardioversion is a medical procedure used to convert this irregular rhythm back to a normal, regular heart rhythm. Dronedarone is then prescribed to help maintain this regular rhythm after a successful cardioversion.

Are there any specific foods or drinks I should avoid while taking dronedarone?

Yes, you should not drink grapefruit juice while taking dronedarone. A chemical in grapefruit juice can increase the amount of dronedarone in your bloodstream, which may increase your risk of experiencing side-effects.

What should I do if I forget to take a dose of dronedarone?

If you miss a dose, take it with something to eat as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose and just take your next dose when it's due. Do not take two doses together to compensate for a forgotten one.

How long will I need to take dronedarone?

Treatment with dronedarone can be long-term. You should continue taking the tablets regularly unless your doctor or a healthcare professional advises you otherwise.

What information should I provide to my doctor before starting dronedarone?

Before starting dronedarone, it's important to inform your doctor if you are pregnant, trying to conceive, or breastfeeding. Also, tell them if you have any liver or kidney problems, other heart conditions, or if you've had an allergic reaction to any medicine, especially experiencing breathing problems with amiodarone. It's also crucial to mention all other medicines you are taking, including over-the-counter, herbal, and complementary medicines, and if you are taking any anticoagulant medicines like apixaban or rivaroxaban.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 18 Sept 2026
  • 19 Sept 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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