Danazol capsules
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 26 Nov 2024
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Clinical author's note Michael Stewart 26/11/2024: Danol® capsules have been discontinued in the UK. At the time of review there are no licensed products containing danazol available in the UK. However danazol is available as a specially manufactured medicine or as an imported medicine. Products are still available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Start taking danazol on the first day of your period unless you have been told otherwise. You can take the capsules either before or after meals.
It is important that you do not become pregnant while on danazol. Follow your doctor's advice about suitable contraception.
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About danazol
Typ av medicin | A gonadotrophin inhibitor |
Används för | Endometriosis; breast cyst pain |
Även kallad | Danol® (discontinued); Cyclomen® (in Canada) |
Tillgänglig som | Kapslar |
Danazol works by altering the levels of some of your body's hormones. It is used to treat a number of different conditions.
Endometrios is a condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere in your body, often in the pelvic area or abdomen. It can cause painful periods and persistent pain in the pelvic area, as well as other symptoms. By altering the levels of your hormones, danazol will help to relieve these symptoms.
Danazol is also prescribed to ease severe pain and tenderness associated with breast cyst disease (where other treatments have proved unhelpful). Breast cysts are small lumps which are found in the breast, but which are not cancerous.
In addition to the two conditions above, danazol is also prescribed by specialist doctors for people with a condition known as hereditary angio-oedema (although it is not licensed for this condition). If you have been prescribed it for this reason, please speak with your doctor if you have any questions about your treatment.
Before taking danazol
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking danazol it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
Om du har en hjärtsjukdom.
If you have any vaginal bleeding other than your regular period.
If you have ever had an unwanted blood clot (thrombosis), or stroke.
If you have any of the following conditions: epilepsy, diabetes (diabetes mellitus), high blood pressure, migraine, or a blood fat (lipid) disorder.
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
If you have either of the following blood disorders: polycythaemia or porphyria.
If you know you have a type of cancer which is affected by hormones.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take danazol
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about danazol, and will also provide you with a full list of side-effects which you could experience from taking it.
You should start taking danazol on the first day of your next period unless you have been told otherwise.
Your doctor will tell you how many capsules to take each day, and when you should take them. As a guide, for the treatment of endometriosis or breast pain, danazol is usually taken 2-4 times daily for 3-6 months. Take the capsules exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you.
Swallow the capsules whole with a drink of water - do not chew or open them before you swallow.
You can take danazol capsules either before or after meals, but try to take your doses at the same times each day, as this will help you to remember to take them regularly.
If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållTry to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor may want you to have some blood tests during this treatment.
It is important that you do not become pregnant while you are on danazol. If appropriate, you and your partner should use a non-hormonal method of contraception, such as a condom. This is because hormonal methods (such as 'the pill' or 'mini pill') will not work. Speak with your doctor if you need further advice about what methods of contraception are suitable for you to use.
It is best not to drink alcohol while you are on danazol. This is because drinking alcohol while taking danazol could make you feel sick or short of breath.
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Can danazol cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with danazol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Danazol side-effects | Vad kan jag göra om jag upplever detta? |
Feeling sick (nausea), stomach pain | Stick to simple foods (avoid rich or spicy meals) |
Feeling dizzy or tired, eyesight changes | If this happens, do not drive and do not use tools or machines while affected. Let your doctor know about any eyesight changes |
Headache, other aches and pains | Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or continues, speak with your doctor |
Increased growth of hair (particularly on your body or face), voice changes, hair loss similar to male baldness | Prata med din läkare om detta as soon as possible. An alternative treatment may be more suitable for you |
Acne, skin rash, muscle cramps, mood changes, changes in your desire for sex, increased appetite and weight changes, irregular menstrual periods, vaginal dryness and irritation, hot flushes, reduced breast size, a feeling that your heart is racing | Om något av dessa blir besvärligt, tala med din läkare |
Viktigt: if you experience any of the following rare but possibly serious symptoms, please speak with your doctor straightaway:
A severe headache and sickness (nausea and vomiting).
Any yellowing of your skin or of the whites of your eyes (jaundice).
Any painful swelling of your arms or legs, or sudden chest pain.
Any bruising that you can't explain. This could be a sign of a blood disorder.
Om du upplever några andra symtom som du tror kan bero på kapslarna, vänligen tala med din läkare eller apotekare för vidare råd.
How to store danazol
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment which medicines you are taking.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vidare läsning och referenser
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 26 Nov 2027
26 Nov 2024 | Senaste versionen

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