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Isosorbidmononitrat

Tardisc, Xismox

Isosorbide mononitrate helps to prevent angina chest pain from developing.

It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain.

The most common side-effect is headache. This should pass after a few days.

About isosorbide mononitrate

Typ av medicin

A nitrate

Används för

Angina prevention; heart failure

Även kallad

Carmil® XL, Chemydur® XL, Elantan® LA, Imdur®, Isib® XL, Ismo®, Isodur® XL, Isotard® XL, Medomon® XL, Modisal® XL, Monomax® SR, Monomil® XL, Monosorb® XL, Nyzamac® SR, Relosorb® XL, Tardisc® XL, Trangina® XL, Xismox® XL, Zemon® XL,

Tillgänglig som

Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules

Isosorbide mononitrate helps to prevent angina chest pain from developing. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. The narrowing makes it more difficult for blood to flow to your heart muscle.

Isosorbide mononitrate works in two ways. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle.

Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with hjärtsvikt. This is a condition where the heart does not beat as efficiently as it should.

Before taking isosorbide mononitrate

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • Om du har några problem med hur din lever fungerar, eller några problem med hur dina njurar fungerar.

  • Om du har lågt blodtryck.

  • If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia).

  • Om du har en underaktiv sköldkörtel.

  • If you have an eye condition called glaucoma.

  • If you have recently had a head injury or a heart attack.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction.

How to take isosorbide mononitrate

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate.

  • Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Longer-acting tablets and capsules are taken once daily in the morning. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. You can take your doses either before or after meals.

  • Swallow the tablet/capsule whole - do not chew or crush it before you swallow. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.

Få ut det mesta av din behandling

  • Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Glyceryl trinitrate (GTN) is commonly prescribed for this.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress

  • The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. It is important that you follow the instructions your doctor gives to you about when to take your doses.

  • It is best not to drink alcohol while you are on isosorbide mononitrate. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed.

  • Om du ska genomgå en operation eller tandbehandling, kom ihåg att informera den som utför behandlingen om vilka mediciner du tar.

  • If you buy any medicines, please check with a pharmacist that they are suitable for you to take with isosorbide mononitrate.

Can isosorbide mononitrate cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with isosorbide mononitrate. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common isosorbide mononitrate side-effects

Vad kan jag göra om jag upplever detta?

Huvudvärk

Ask your doctor or pharmacist to recommend a suitable painkiller. This side-effect usually disappears after a few days

Känner du dig yr eller trött

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Fast heartbeat; flushing

Om någon av dessa blir besvärlig, tala med din läkare

Om du upplever några andra symtom som du tror kan bero på medicinen, vänligen tala med din läkare eller apotekare för vidare råd.

How to store isosorbide mononitrate

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Vanliga frågor

What is the difference between isosorbide mononitrate and glyceryl trinitrate (GTN)?

Isosorbide mononitrate is prescribed to prevent angina chest pain from developing in the first place. Glyceryl trinitrate (GTN) or other short-acting nitrates are used to treat the pain of an angina attack if and when it occurs.

Can I stop taking isosorbide mononitrate if I feel better?

You should not stop taking isosorbide mononitrate unless advised by your doctor. This medicine is prescribed to prevent angina, and stopping it could lead to the return of your symptoms. Regular appointments with your doctor are important to monitor your progress.

What if I accidentally chew or crush my isosorbide mononitrate tablet or capsule?

It is important to swallow the tablet or capsule whole. They are specially designed to release the medicine in a controlled way over time. Chewing or crushing them could alter how the medicine is absorbed and may not work as intended.

Can isosorbide mononitrate become less effective over time?

Yes, over time your body can become used to isosorbide mononitrate, a phenomenon known as tolerance, which can make the medicine less effective. To help prevent this, if you are taking more than one dose daily, your doses might be scheduled at specific intervals that are not equally spread out. It's crucial to follow your doctor's instructions precisely regarding dose timings.

What should I do if I think I've taken too much isosorbide mononitrate?

Never take more than the prescribed dose. If you suspect an overdose, you should go to the accident and emergency department of your local hospital immediately. Remember to bring the medicine container with you, even if it's empty.

Vidare läsning och referenser

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
  • Nästa granskning: 16 okt 2027
  • 20 okt 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani

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