Nabumetone for pain and inflammation

About nabumetone

Anti-inflammatoriska smärtstillande medel like nabumetone are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Nabumetone is prescribed for people with artros or reumatoid artrit. Det lindrar smärta och minskar inflammation.

Nabumetone works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking nabumetone it is important that your doctor knows:

• Om du någonsin har haft ett magsår eller duodenalsår, eller om du har en inflammatorisk tarmsjukdom som Crohns sjukdom eller ulcerös kolit.

• Om du har astma eller någon annan allergisk sjukdom.

• Om du är gravid, försöker bli gravid eller ammar.

• Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

• If you have a heart condition or a problem with your blood vessels or circulation.

• Om du har högt blodtryck.

• If you have any blood clotting problems.

• Om du har en bindvävssjukdom som systemisk lupus erythematosus. Detta är ett inflammatoriskt tillstånd som också kallas lupus eller SLE.

• Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

• If you have ever had an allergic reaction to any other NSAID (such as aspirin, naproxen, ibuprofen, and indometacin), or to any other medicine.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nabumetone, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• The usual dose is one or two 500 mg tablets taken daily. You will be asked to take the tablets at the end of the day. If your doctor prescribes a higher dose than this for you, you will be asked to take a dose in the morning as well. This will be in addition to the dose you take in the evening. Take nabumetone exactly as your doctor tells you to.

• You should take nabumetone after a meal, or with a snack. Taking the tablets with some food will help to protect your stomach from side-effects such as indigestion and stomach irritation.

• If you forget to take a dose, don't worry, just take the next dose when it is due. Do not take two doses together to make up for a missed dose.

• Your doctor will try to prescribe you the lowest dose for the shortest time in order to reduce the risk of side-effects. If you need to take nabumetone over a period of time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

• Försök att hålla alla regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as nabumetone. If this happens to you, you should stop taking nabumetone and see a doctor as soon as possible.

• Det är känt att det finns en liten ökad risk för hjärt- och kärlproblem hos personer som tar vissa antiinflammatoriska smärtstillande medel under lång tid. Din läkare kommer att förklara detta för dig och kommer att ordinera den lägsta lämpliga dosen för den kortaste tiden för att minska risken. Ta inte mer än den rekommenderade dosen.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because you should not take nabumetone with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought 'over the counter'.

• Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with nabumetone. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Viktigt: if you experience any of the following less common but possibly serious symptoms, stop taking nabumetone and contact a doctor for advice straightaway:

• Om du har några andningssvårigheter som väsande andning eller andfåddhet.

• Om du har några tecken på en allergisk reaktion, såsom svullnad runt munnen eller ansiktet, eller ett allvarligt kliande hudutslag.

• If you pass blood or black stools, bring up blood, or have severe stomach pains.

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

• Förvara alla läkemedel utom räckhåll och synhåll för barn.

• Förvara på en sval, torr plats, borta från direkt värme och ljus.