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Celecoxib capsules for pain and inflammation

Celebrex

Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 15 Apr 2023

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Celecoxib is a medicine called a non-steroidal anti-inflammatory drug. It is also known as an 'NSAID'.

Before you take celecoxib, let your doctor know if you have ever had a bad reaction to any other anti-inflammatory painkiller.

The most common side effects of celecoxib include diarrhoea, indigestion, abdominal pain, and feeling sick (nausea).

At a glance

  • Celecoxib is a painkiller and anti-inflammatory medicine.

  • It treats pain and inflammation in conditions like osteoarthritis and rheumatoid arthritis.

  • Common side effects include indigestion, headache, and dizziness.

  • Do not take celecoxib if you have certain conditions, including stomach ulcers or heart problems.

  • If you have wheezing or breathlessness, stop taking it and see a doctor.

  • Celecoxib capsules can be taken with or without food.

This summary has been automatically generated from the article content to help readers quickly understand the key points.

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About celecoxib

Typ av medicin

A selective inhibitor of cyclo-oxygenase-2 non-steroidal anti-inflammatory drug (NSAID)

Används för

Relief of pain and inflammation in osteoarthritis, rheumatoid arthritis or ankylosing spondylitis

Även kallad

Celebrex®

Tillgänglig som

Kapslar

What is celecoxib used for?

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Celecoxib is a type of anti-inflammatory painkiller called non-steroidal anti-inflammatory drugs (NSAIDs), or just 'anti-inflammatories'.

It is used to treat painful rheumatic conditions such as artros, reumatoid artrit och ankyloserande spondylit. Det lindrar smärta och minskar inflammation.

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How does celecoxib work?

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Celecoxib reduces pain and swelling by blocking an enzyme (COX-2) that causes inflammation. This helps ease pain and stiffness in arthritis.

Side effects of celecoxib

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Common side effects of celecoxib include:

  • Känner dig yr.

  • Diarré.

  • Headache.

  • Indigestion.

  • Farting (wind).

  • Mag- (buk) smärta.

  • Illamående.

You will find a full list in the manufacturer's information leaflet supplied with your medicine.

De oönskade effekterna förbättras ofta när din kropp anpassar sig till den nya medicinen, men prata med din läkare eller apotekare om några biverkningar fortsätter eller blir besvärliga.

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How to manage celecoxib side effects

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Common celecoxib side effects

Vad kan jag göra om jag upplever detta?

Känner dig yr

Kör inte och använd inte verktyg eller maskiner förrän du mår bättre

Diarré

Drick mycket vatten för att ersätta förlorade vätskor

Huvudvärk

Drink plenty of water. If the headaches continue, speak with your doctor

Indigestion, wind, stomach pain

Stick to simple meals - avoid rich or spicy foods. If the discomfort continues, speak with your doctor

High blood pressure, swollen ankles, joint pain, fluid retention, flu-like illness, runny nose, cough, chest or urinary infections, and difficulties sleeping

Om något av dessa blir besvärligt, tala med din läkare

Viktigt: if you experience any of the following less common but more serious symptoms, stop taking celecoxib and contact your doctor for advice straightaway:

  • Om du har några andningssvårigheter som väsande andning eller andfåddhet.

  • Om du har några tecken på en allergisk reaktion, såsom svullnad runt munnen eller ansiktet, eller ett allvarligt kliande hudutslag.

  • If you pass blood or black stools, bring up (vomit) blood, or have abdominal pains.

Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.

Who should not take celecoxib?

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Some medicines aren’t suitable for everyone. Before taking celecoxib, your doctor needs to know:

  • Om du har astma eller någon annan allergisk sjukdom.

  • If you have had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohns sjukdom or ulcerös kolit.

  • Om du är gravid, försöker bli gravid eller ammar.

  • Om du är under 18 eller över 65 år gammal.

  • Om du har lever- eller njurproblem.

  • Om du har en hjärtsjukdom eller problem med dina blodkärl eller cirkulation.

  • If you have högt blodtryck.

  • Om du någonsin har haft problem med blodkoagulation.

  • If you have a connective tissue disorder, such as systemic lupus erythematosus (an inflammatory condition also called lupus, or SLE).

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • If you have ever had an allergic reaction to aspirin or other NSAID (such as indometacin, diclofenac, and ibuprofen), or to any other medicine. Or if you are allergic to a sulfonamide medicine.

How to take celecoxib

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  • Read the information leaflet in the pack before starting celecoxib to learn about side effects.

  • Take celecoxib exactly as prescribed, usually 1 capsule once or twice a day (100 mg or 200 mg).

  • Take it at the same time(s) each day to help you remember.

  • Swallow capsules whole with water, or open and mix with soft food if needed, then drink water. You can take it with or without food.

  • If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Ta inte två doser samtidigt.

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  • Your doctor will prescribe the lowest dose for the shortest time to reduce side effects.

  • For long-term use you may be given another medicine to protect your stomach.

  • Keep regular doctor appointments so your progress and blood pressure can be checked.

  • Pain should improve within a few days; if not better after two weeks, talk to your doctor.

  • If you have asthma and develop wheezing or breathlessness, stop taking celecoxib and see a doctor.

  • Check with a pharmacist before buying other medicines - don’t take celecoxib with other anti-inflammatory painkillers.

  • Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

How to store celecoxib

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  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

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Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Vanliga frågor

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How long does it take for celecoxib to work?

Celecoxib usually starts to work within 30-60 minutes of taking it, with pain relief typically lasting for 12-14 hours. For chronic inflammation, pain and swelling usually begin to improve after a week of regular use.

Can you drink alcohol with celecoxib?

Yes, you can drink small amounts of alcohol with celecoxib, however it can increase the risk of stomach irritation and bleeding. It is best to avoid or limit alcohol until your treatment is finished.

Is it safe to take celecoxib during pregnancy?

Celecoxib is not recommended during pregnancy as it can harm the baby. If you are pregnant or planning to become pregnant, let your doctor know.

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Vanliga frågor

What is the common dosage of celecoxib?

Celecoxib is typically prescribed as 1 capsule once or twice a day, in either a 100 mg or 200 mg strength, as directed by your doctor. It's important to take it exactly as prescribed.

How long should I take celecoxib for pain relief from arthritis?

Your doctor will aim to prescribe the lowest effective dose for the shortest possible time to minimise potential side effects. For arthritis, the pain should usually improve within a few days. If you don't notice an improvement after two weeks, you should speak with your doctor.

Can celecoxib be taken with or without food?

Yes, celecoxib capsules can be taken with or without food. You can swallow the capsules whole with water, or if needed, you can open them and mix the contents with soft food, then drink water.

What should I do if I forget to take a dose of celecoxib?

If you miss a dose of celecoxib, you should take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses together to make up for a forgotten dose.

Are there any medicines I should avoid while taking celecoxib?

Yes, you should check with a pharmacist before buying any other medicines, especially other anti-inflammatory painkillers, as you should not take celecoxib with them. Always inform your doctor or pharmacist about all medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines.

How should I store celecoxib at home?

You should keep celecoxib, like all medicines, out of the reach and sight of children. Store it in a cool, dry place, away from direct heat and light, to ensure its effectiveness.

These questions and answers have been generated from the information in this article.

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewerView full bio

Author image

Dr Colin Tidy, MRCGP

General Practitioner, Medical Author

MBBS, MRCGP, MRCP (Paediatrics), DCH

Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.

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