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Ticagrelor tabletter

Brilique

You will be given two 90 mg tablets to take as your first dose. After this, take one 90 mg tablet twice a day, preferably in the morning and evening.

It is likely you will be prescribed ticagrelor for a period of up to twelve months. If there is a need for you to take it for longer than this, your dose will be reduced to 60 mg twice daily.

The most common unwanted effects are an increased risk of bleeding, and feeling short of breath.

Överblick

  • Ticagrelor is an antiplatelet medicine that helps prevent blood clots.

  • It is prescribed for people who have acute coronary syndrome or have had a heart attack.

  • You will also take aspirin alongside ticagrelor.

  • Take your tablets twice a day, every day, at around the same times.

  • Tell your doctor if you have a bleeding condition, breathing difficulties, or problems with your liver.

  • Shortness of breath and bleeding/bruising are common side-effects.

About ticagrelor tablets

Typ av medicin

An antiplatelet medicine

Används för

Preventing clots from forming in blood vessels (in people with acute coronary syndrome or in people who have previously had a heart attack)

Även kallad

Brilique®

Tillgänglig som

Tablets and melt-in-the-mouth (orodispersible) tablets

In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem. It may mean that you have had a hjärtattack, or that you have angina pain that is not well controlled. Antiplatelet medicines reduce the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of an artery and forming a thrombus. This reduces the chances of you having a heart attack or stroke.

Ticagrelor is an antiplatelet medicine. Your doctor will also prescribe aspirin for you to take alongside ticagrelor. Aspirin is another antiplatelet medicine. A course of treatment with ticagrelor typically lasts for up to 12 months, whereas treatment with aspirin is likely to be lifelong.

If you require a procedure to open a blocked artery in your heart because you have already had a heart attack or because you have unstable angina, you could be given a single dose of ticagrelor during the procedure.

Before taking ticagrelor tablets

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking ticagrelor tablets it is important that your doctor knows:

  • If you have a condition which causes bleeding, such as a recent wound or a stomach ulcer.

  • If you have any breathing difficulties, such as asthma or chronic obstructive pulmonary disease (COPD). Ticagrelor can make these conditions worse.

  • If you have any other heart condition, or an abnormal heart rate.

  • If you have ever had a stroke caused by bleeding in your brain, a condition called intracranial haemorrhage.

  • If you have ever been told you have high blood levels of uric acid, or gout.

  • Om du är gravid eller ammar.

  • If you have any problems with the way your liver works.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

How to take ticagrelor tablets

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ticagrelor, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take the tablets exactly as your doctor tells you to. On the first day of treatment, you will be given two 90 mg tablets to take at the same time so that you get sufficient medicine into your bloodstream to begin with. After this, you will be prescribed a dose of 90 mg twice a day. A course of treatment with ticagrelor often lasts for up to 12 months. If you have had a heart attack, your doctor may want you to continue to take ticagrelor even after the 12-month course has finished. If so, it will be at a lower dose of 60 mg twice daily.

  • Try to take your doses around the same times of day each day, preferably in the morning and the evening. This will help you to remember to take ticagrelor regularly.

  • Most people find that they can swallow the tablet whole with a drink of water. However, you can crush the tablet into a fine powder and take it stirred into a small glass of water if you prefer, providing that you swallow the mixture straight after making it.

  • For people who have swallowing difficulties there is also a melt-in-the-mouth (orodispersible) tablet. If you have been prescribed this tablet, tear open the blister foil and carefully remove the tablet. Place the tablet on your tongue where it will dissolve in a few seconds. You can swallow it with or without a drink of water. It is a good idea to have a few sips of water before taking your tablet, so that your mouth is moist. Make sure your hands are dry when handling the tablet.

  • You can take ticagrelor tablets either with or without food.

  • If you forget to take a dose, take it as soon as you remember, unless it is nearly time for your next dose. In which case take the next dose when it is due and leave out the forgotten dose. Do not take two doses together to make up for a missed dose.

Få ut det mesta av din behandling

  • Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with ticagrelor tablets. Some medicines, called non-steroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding, so check with a pharmacist before you buy any painkillers. Also, do not take any preparations containing aspirin that have not been prescribed for you by your doctor. Several medicines for pain relief and cold relief that can be bought at retail outlets contain aspirin or ibuprofen - you should not take these, so check the label carefully before you buy.

  • If you are due to have an operation, before the treatment is due, tell the person carrying out the treatment that you are taking ticagrelor. This is because any bleeding may take longer than normal to stop so your treatment may need to be interrupted for a short while before the operation. You should also let your dentist know that you are taking ticagrelor before you receive any dental treatment.

Can ticagrelor tablets cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with ticagrelor. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common ticagrelor side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Feeling short of breath

Let your doctor know if this becomes troublesome

Bleeding, bruising, nosebleeds. Stopping bleeding could take longer than normal

Let your doctor know if you notice any unusual or unexpected bleeding or bruising

High levels of uric acid (a symptom of gout)

Your doctor may check for this

Common ticagrelor side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling dizzy or faint

Om det är besvärligt, prata med din läkare

Huvudvärk

Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, kontakta din läkare

Gastric upset (such as feeling sick (nausea), indigestion, constipation or diarrhoea)

Om det är besvärligt, prata med din läkare

Skin rash

Om det är besvärligt, prata med din läkare

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

How to store ticagrelor tablets

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  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

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Vanliga frågor

How does ticagrelor prevent heart attacks and strokes?

Ticagrelor is an antiplatelet medicine. This means it reduces the 'stickiness' of cells in your blood called platelets. By making platelets less likely to stick together, ticagrelor helps prevent the formation of blood clots (thrombi) inside your arteries. These clots can reduce blood flow to your heart, potentially leading to a heart attack, or to your brain, which can cause a stroke.

Can I stop taking ticagrelor if I feel better?

No, you should not stop taking ticagrelor without speaking to your doctor. It is prescribed to prevent serious conditions like heart attacks and strokes. Your doctor will determine the appropriate length of your treatment, which can range from several months to ongoing, depending on your health condition.

What should I do if I experience bleeding or bruising while taking ticagrelor?

Bleeding, bruising, and nosebleeds are common side effects of ticagrelor, and it may take longer than usual for bleeding to stop. You should inform your doctor if you notice any unusual or unexpected bleeding or bruising, or if these issues become troublesome.

Can ticagrelor affect my breathing?

Yes, ticagrelor can sometimes cause or worsen breathing difficulties like shortness of breath. If you experience shortness of breath that becomes troublesome, you should let your doctor know.

Are there any over-the-counter medicines I should avoid while taking ticagrelor?

Yes, you should check with a pharmacist before buying any over-the-counter medicines, especially pain relievers. Some medicines, such as non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, can increase the risk of bleeding when taken with ticagrelor. Also, avoid any preparations containing aspirin unless specifically prescribed by your doctor, as many cold and pain remedies contain it.

What if I need surgery or dental work while on ticagrelor?

It is very important to tell your doctor, dentist, or any healthcare professional performing a procedure that you are taking ticagrelor. This is because ticagrelor affects blood clotting, and bleeding might take longer to stop. Your treatment with ticagrelor may need to be temporarily interrupted before an operation to minimise bleeding risks.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Helen Allen, MPharm

Apotekare, Medicinsk Författare

MPharm

Helen Allen kvalificerade sig som apotekare 1979 och tillbringade 3 år som författare av läkemedelsinformationsbroschyrer för EMIS.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

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