Botulinum toxin type A for migraine
Botox
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 19 Sept 2023
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Botulinum toxin type A is a specialist treatment for migraine.
To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days.
It will be given by multiple injections into the muscles around your head and neck.
If you experience any difficulty swallowing, speaking, or breathing after the treatment, speak with your doctor immediately.
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Video picks for Läkemedel för nervsystemet
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About botulinum toxin type A
Typ av medicin | A bacterial neurotoxin |
Används för | To prevent headaches associated with chronic migraine in adults |
Även kallad | Onabotulinumtoxin A (in US); Alluzience®; Azzalure®; Bocouture®; Botox®; Nuceiva®; Xeomin® |
Tillgänglig som | Injection |
Botulinum toxin type A is a protein substance which is produced by the bacterium Clostridium botulinum. It is a neurotoxin which means that it interferes with the way nerves work. To be eligible for this treatment you must have headaches for 15 or more days each month, with migraine headaches being on at least eight of these days. You must also have tried several other medicines to prevent migraine before this treatment is prescribed for you.
Botulinum toxin type A is thought to work in chronic migraine by relaxing muscles and by blocking the pain signals which are involved in the development of a migraine. These actions may have the effect of stopping a migraine headache from being triggered.
Botulinum toxin injections are also used for other reasons (including cosmetic purposes, muscle spasms, bladder problems, and excessive sweating). This leaflet does not cover the use of botulinum toxin type A in these ways.
Before being treated with botulinum toxin type A
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before being treated with botulinum toxin type A for migraine, make sure that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have an infection or any swelling near any of the areas that will be injected.
If you have any muscle problems, particularly any muscle weakness.
If you have ever had any difficulty in swallowing or with your breathing.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How you will be given botulinum toxin type A
Tillbaka till innehållBefore you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about Botox® and will provide you with a full list of the side-effects which you may experience from having it.
You will be given botulinum toxin type A by a doctor who is trained in the use of this treatment. It will be injected into the muscles around your head and neck in several different places.
If the treatment proves successful for you, your doctor is likely to recommend that it is repeated every 12 weeks.
Få ut det mesta av din behandling
Tillbaka till innehållIf you are having an operation or dental treatment, tell the person carrying out the treatment that you have received botulinum toxin type A.
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Can botulinum toxin type A cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with botulinum toxin type A. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects may occur following a treatment session even if you have been free from side-effects on previous treatments. You should speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common Botox® side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Pain at the sites where you have been injected, neck and muscle pain or stiffness, muscle weakness, skin rash and itching | These should soon pass, but if any becomes troublesome, speak with your doctor |
Worsening of headache or migraine | Prata med din läkare om detta |
Eyelid drooping or swelling, paralysis of the face | Prata med din läkare om detta |
Viktigt: if you experience any difficulty swallowing, speaking, or breathing, speak with your doctor immediately or go to your local accident and emergency department straightaway.
If you experience any other symptoms which you think may be due to the treatment, speak with your doctor or pharmacist for further advice.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
If you buy any medicines, check with a pharmacist that they are safe to use alongside this treatment.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Botox® 50, 100 and 200 Allergan Units; AbbVie Ltd, The electronic Medicines Compendium. Dated April 2023.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 18 Sept 2026
19 Sept 2023 | Senaste versionen

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