Modafinil tablets
Provigil
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 14 Aug 2023
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Take modafinil at the same times each day to avoid missing any doses.
The most common side-effects include headache, feeling sick (nausea) and feeling dizzy.
You should not become pregnant whilst taking modafinil. Ask your doctor about which contraceptive methods are suitable for you while you are taking modafinil - hormonal contraceptives are not suitable.
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About modafinil
Typ av medicin | A central nervous system stimulant |
Används för | Daytime sleepiness associated with narcolepsy in adults |
Även kallad | Provigil® |
Tillgänglig som | Tabletter |
Narcolepsy is a long-term problem that affects your sleep. You feel excessively tired during the daytime but have disturbed night-time sleep. You can also have sleep attacks where you fall asleep at inappropriate times during the day without any warning.
Although there is no cure for narcolepsy, modafinil can help to control your symptoms. Modafinil works by stimulating the central nervous system to increase your alertness and reduce excessive sleepiness during the day.
Before taking modafinil
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking modafinil it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your liver works or any problems with the way your kidneys work.
If you have a heart condition or high blood pressure (hypertension).
If you have ever had a mental health problem such as depression, psychosis or mania.
If you have ever had a problem with drug or alcohol misuse.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Clinical author's note Michael Stewart 01/03/2020: Based on post-marketing reports from the USA, modafinil (Provigil®) may harm an unborn child. Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping. Discuss with your doctor which forms of contraception are suitable for you, as hormonal contraceptives are made less effective by modafinil. Alternative treatment options for narcolepsy should be used during pregnancy, such as behaviour modifications, good sleeping habits and scheduled daytime naps.
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How to take modafinil
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about modafinil and will provide you with a full list of the side-effects which you may experience from taking it.
Take the tablets exactly as your doctor tells you to. There are two strengths of tablet available - 100 mg and 200 mg. When you first start modafinil it is usual to be prescribed a dose of 200 mg daily. You may be asked to take this as a single dose of 200 mg in the morning, or divided into 100 mg in the morning and 100 mg at midday. Your doctor or pharmacist will tell you which is right for you. Your dose may be increased after a little while, depending upon your symptoms.
Take your doses with a drink of water to help you swallow the tablet. Do not break or crush the tablet - it should be swallowed whole. You can take modafinil before or after food.
If you forget to take a dose, miss out the forgotten dose completely but make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållKeep your regular appointments with your doctor so that your progress can be monitored. You may need to have your blood pressure and heart rate checked regularly.
Modafinil can cause blurred vision or dizziness in some people and therefore it may affect your ability to use tools or machines, so take care when using them. Sleepiness associated with your condition can add to this.
Taking modafinil is not a replacement for a good sleep routine. It is still important that you aim to get around eight hours of sleep at night if possible. You should try to go to sleep and get up at about the same time each day.
In the UK, you are required by law to let the Driver and Vehicle Licensing Authority (DVLA) know if you are diagnosed with narcolepsy. You may be allowed to drive again when your symptoms are well controlled with medication, but you will need to have regular reviews. Your doctor will advise you about this.
Modafinil should not be used during pregnancy. Women of childbearing potential must use effective contraception during treatment with modafinil and for two months after stopping.
Hormonal contraceptives, including oral contraceptive pills, implants, intrauterine contraceptive devices (IUCDs) and contraceptive patches, are less effective when used with modafinil and are therefore not recommended. Speak to your doctor about which contraceptive methods are suitable for you while you are taking modafinil.
If you are planning to become pregnant you should stop taking modafinil and try alternative treatment options such as good sleep habits and scheduled daytime naps.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking modafinil.
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Can modafinil cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with modafinil. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common modafinil side-effects | Vad kan jag göra om jag upplever detta? |
Huvudvärk | This usually passes within a day or so, but in the meantime, ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Feeling sick (nausea), indigestion, stomach ache | Håll dig till enkla måltider - undvik rik eller kryddstark mat |
Diarré | Drink plenty of water to replace lost fluids |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day |
Feeling dizzy or tired, blurred vision | Take special care when using tools or machines |
Flushing, loss of appetite, nervousness, difficulty sleeping, anxiety, depression, confusion or confused thinking, chest pain, fast heartbeat, numbness or tingling feelings | Speak with your doctor if any of these continue or become troublesome |
Viktigt: if you experience any of the following symptoms, stop taking modafinil and contact your doctor for advice omedelbart:
A rash or blisters on the skin.
Any changes to your mood, behaviour, or thinking.
Any suicidal thoughts, or thoughts about harming yourself.
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store modafinil
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du köper några läkemedel, kontrollera med en apotekare att de är lämpliga att ta tillsammans med dina andra läkemedel.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Modafinil (Provigil®) 100 mg and 200 mg tablets; Teva Pharma B.V., The electronic Medicines Compendium. Dated October 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 13 Aug 2026
14 Aug 2023 | Senaste versionen

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