Loprazolam for sleeping problems
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 19 dec 2022
Uppfyller patientens redaktionella riktlinjer
- Ladda nerLadda ner
- Dela
- Language
- Diskussion
- Ljudversion
- Add to preferred sources on Google
Loprazolam will help you to sleep. You will be prescribed a short course of treatment only.
Take the tablet just before you go to bed.
The effects of loprazolam can last into the following day; it is likely to impair your reactions and your ability to drive. Do not drive and do not use tools or machines while affected.
At a glance
Loprazolam is a benzodiazepine medicine used for short-term treatment of sleeping problems in adults.
It is usually taken just before bed, but generally only for a short period.
Taking it for longer can lead to tolerance, dependence, or addiction.
Loprazolam can cause drowsiness, affect driving, and increase the effects of alcohol.
Do not drive if you feel drowsy or your reactions are impaired.
I den här artikeln:
Video picks for Läkemedel för nervsystemet
Fortsätt läsa nedan
About loprazolam
Typ av medicin | A benzodiazepine |
Används för | Sleeping problems (insomnia) in adults |
Tillgänglig som | Tabletter |
Poor sleep (insomnia) is fairly common but does not usually last for long. If you have problems sleeping, it may mean that you have difficulty getting off to sleep, or you may wake up for long periods during the night, or you may wake up too early in the morning. 'Sleeping tablets' like loprazolam are considered a last resort, but are sometimes prescribed for a short period of time to help with a particularly bad spell of insomnia.
Loprazolam works by affecting the way certain brain chemicals (neurotransmitters) transmit messages. This has a calming effect which helps you to sleep. It works well in the short term, with one week's treatment normally being sufficient, although up to three weeks of treatment are sometimes required. If you take it for longer, the medicine may lose its effect (you may become tolerant to the effect) and when you stop taking it you may develop withdrawal symptoms. You may need to keep taking the medicine to avoid the withdrawal symptoms. This is known as drug dependence.
In addition, you may become addicted to loprazolam. Addiction is different from dependence. You have an overwhelming craving for a drug, so that you feel compelled to take it even though it is harming you physically or affecting your life and relationships.
Before taking loprazolam
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking loprazolam it is important that your doctor knows:
Om du är gravid eller ammar.
If you have any breathing problems.
Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.
If you have a mental health problem. This includes conditions such as psychosis, depression, and personality disorders.
If you have ever had a drug or alcohol addiction.
If you have a condition causing severe muscle weakness, called myasthenia gravis.
If you have a rare inherited blood disorder called porphyria.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel som kan köpas utan recept, samt växtbaserade och komplementära läkemedel.
Fortsätt läsa nedan
How to take loprazolam
Tillbaka till innehållBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about loprazolam, and it will also provide you with a full list of the side-effects which you could experience from taking it.
The usual dose is one tablet (1 mg) taken just before going to bed. Your doctor may recommend that you take a dose for just a few days, or only on certain days of the week. It is important that you take loprazolam exactly as your doctor tells you to.
Få ut det mesta av din behandling
Tillbaka till innehållTry to keep any appointments with your doctor. This is so your doctor can check how you are feeling.
The effects of loprazolam can last into the following day; please be aware that it is likely to impair your judgement and reactions, and so affect your ability to drive. It is an offence to drive while your reactions are impaired, so do not drive until you know how you react, especially when you first start treatment. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.
Do not drink alcohol while you are on loprazolam. It will increase the risk of sedative side-effects.
If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking a benzodiazepine. This is because loprazolam increases the effects of some anaesthetics.
Your doctor may recommend that you reduce your dose gradually when it is time to stop taking it. This is to reduce the risk of you experiencing withdrawal effects. Follow carefully any instructions your doctor gives to you.
Fortsätt läsa nedan
Can loprazolam cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with loprazolam. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common loprazolam side-effects | Vad kan jag göra om jag upplever detta? |
Feeling sleepy or light-headed during the day | Kör inte och använd inte verktyg eller maskiner. Drick inte alkohol |
Feeling unsteady, weak, forgetful, confused, or aggressive | If any become troublesome, speak with your doctor |
Headache, feeling sick (nausea), blurred vision | These should soon pass, but if any are troublesome or you are concerned about them, please speak with your doctor |
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store loprazolam
Tillbaka till innehållKeep all medicines out of the sight and reach of children.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
How does loprazolam help me sleep?
Loprazolam works by affecting certain chemicals in your brain that transmit messages. This creates a calming effect that helps you to fall asleep.
How long should I expect to take loprazolam?
Loprazolam is typically prescribed for a short period. Usually, one week of treatment is enough, but some people might need it for up to three weeks. Taking it for longer can lead to the medicine becoming less effective and may cause withdrawal symptoms when you stop.
Are there any specific activities I should avoid while taking loprazolam?
Yes, it's important to avoid driving or operating machinery because loprazolam can impair your judgment and reactions. You should also not drink alcohol as it increases the risk of sedative side-effects. If you are having an operation or dental treatment, inform the person carrying out the treatment that you are taking loprazolam, as it can increase the effects of some anaesthetics.
What is the difference between drug dependence and addiction with loprazolam?
Drug dependence means you might need to keep taking the medicine to avoid withdrawal symptoms if you stop, often because the medicine loses its effect over time. Addiction is different; it involves an overwhelming craving for the drug, making you feel compelled to take it even if it causes harm or affects your life and relationships.
What should I do if I forget to take my loprazolam dose?
The article states that loprazolam should be taken just before going to bed. It does not provide specific instructions for a missed dose. Always follow your doctor's instructions exactly for how to take this medication.
Vidare läsning och referenser
- Manufacturer's PIL, Loprazolam 1 mg Tablets; Zentiva, The electronic Medicines Compendium. Dated March 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Fortsätt läsa nedan
About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Nästa granskning: 18 jun 2027
19 dec 2022 | Senaste versionen

Fråga, dela, anslut.
Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.
Anmäl dig till Patientens nyhetsbrev
Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.
By subscribing you accept our Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.