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Agomelatintabletter

Valdoxan

Take agomelatine once a day, at bedtime.

It can take a week or two after starting the tablets before the effect builds up and you start to feel the benefit. If you do not feel you have improved after this time, go back and talk with your doctor.

The most common side effects of agomelatine are feeling dizzy or sick (nausea) - these are usually mild and soon pass.

Rarely, agomelatine can affect the way your liver works. If you develop dark urine, pale stools, any yellowing of your skin or the whites of your eyes, pain in your tummy (abdomen), or feel unusually tired, you must let your doctor know about this straightaway.

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About agomelatine

Typ av medicin

A melatonin agonist

Används för

Depression

Även kallad

Valdoxan®

Tillgänglig som

Tabletter

What is agomelatine used for?

Agomelatine is an atypical antidepressant used to treat depression.

Depression is common and symptoms can affect day-to-day life and can become very distressing. Treatments include talking (psychological) treatments and antidepressant medicines.

Our bodies follow a daily cycle, called circadian rhythms, which control sleep and other functions. When these rhythms are disrupted, it can lead to depression. Agomelatine helps depression by restoring this natural balance.

Side effects of agomelatine

The most common side effects of agomelatine are:

  • Illamående.

  • Diarré.

  • Feeling dizzy, tired or sleepy.

  • Huvudvärk

  • Förstoppning.

  • Magont.

  • Sömnsvårigheter.

  • Känner sig orolig.

  • Increased sweating.

  • Back pain.

Du hittar en fullständig lista i tillverkarens informationsblad som medföljer din medicin. De oönskade effekterna förbättras ofta när din kropp anpassar sig till den nya medicinen, men tala med din läkare eller apotekare om något av följande fortsätter eller blir besvärligt.

How to manage agomelatine side effects

Common agomelatine side effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling sick, diarrhoea

Stick to simple foods (avoid fatty or spicy meals) and drink plenty of water

Feeling dizzy, tired or sleepy

Kör inte och använd inte verktyg eller maskiner. Drick inte alkohol

Huvudvärk

Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, kontakta din läkare

Constipation, tummy pain

Try to eat a well-balanced diet containing fresh fruit and vegetables. Drink plenty of water

Difficulty sleeping, feeling anxious, increased sweating, back pain

These effects are usually mild and soon pass but if any become troublesome, speak with your doctor

Viktigt: if you notice any of the following you should contact your doctor straightaway as it could be a sign of a problem with your liver:

  • Dark urine or light-coloured stools.

  • Att vara sjuk (kräkas)

  • Pain in your tummy (abdomen).

  • Any yellowing of your skin or the whites of your eyes (jaundice).

  • Itchy skin or unexplained bruising.

  • Aptitlöshet.

  • Any unexplained flu-like symptoms.

  • Feeling unusually tired or generally unwell.

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

Who should not take agomelatine?

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking agomelatine it is important that your doctor knows:

  • If you are under 18 or over 75 years of age.

  • Om du är gravid eller ammar.

  • Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

  • If you have ever had abnormally 'high' moods or dementia.

  • Om du regelbundet dricker stora mängder alkohol.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel som kan köpas utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take agomelatine

  • Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about agomelatine, and will also provide you with a full list of the side effects which you could experience from taking it.

  • Take agomelatine exactly as your doctor tells you to. The usual dose is one tablet daily. This may be increased in some people to two tablets daily (taken together) after a couple of weeks.

  • You should take the tablets at bedtime. The tablets can be taken either with or without food.

  • If you forget to take a dose, do not worry, just take the next dose when it is due.

Få ut det mesta av din behandling

  • It can take a week or two after starting the tablets before the effect begins to build up, and maybe a few weeks longer before you feel the full benefit from the treatment. Do not stop taking agomelatine after a few days, thinking it is not helping.

  • Try to keep your regular appointments with your doctor. This is because your doctor will want you to have a blood test every few weeks to check that your liver is staying healthy.

    • Your doctor will also give you a booklet to read which explains about what symptoms to look out for as signs that the medicine could be harming your liver. There is a list of these symptoms in the section below on the problems which can be caused by agomelatine.

  • While you feel depressed or are taking agomelatine, you may have thoughts about harming yourself or ending your life. It is very important that you tell your doctor about this straightaway if it happens to you.

  • Taking agomelatine and alcohol is not recommended, so do not drink alcohol during your treatment with this medicine.

  • Smoking can affect the amount of agomelatine in your body. Let your doctor know if you either start or stop smoking while you are taking agomelatine.

  • Your doctor will ask you to carry on taking agomelatine for a while after you feel better. This is to stop your symptoms from returning.

  • There are several types of antidepressants and they differ in their possible side effects. If you find that agomelatine does not suit you then let your doctor know, as another could be found that will suit you.

How to store agomelatine

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Om du köper några läkemedel, kontrollera med en apotekare att de är säkra att ta tillsammans med dina förskrivna läkemedel.

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med förpackningen, även om den är tom.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Vanliga frågor

Is agomelatine a strong antidepressant?

Agomelatine is not considered a “strong” antidepressant in the traditional sense, but it can be effective for some people. It works differently to many other antidepressants, helping regulate sleep as well as mood.

Does agomelatine cause weight gain?

Agomelatine is less likely to cause weight gain than many other antidepressants. While changes in weight can happen for some people, they are not usually common side effects.

What class of drug is agomelatine?

Agomelatine belongs to a class of antidepressants known as melatonergic antidepressants. It works differently from SSRIs and SNRIs by acting on melatonin and serotonin receptors, which may help improve sleep patterns as well as mood.

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