Brimonidine eye drops for glaucoma
Alphagan
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 26 Nov 2024
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Brimonidine eye drops are used to control increased pressure within your eye (glaucoma).
Remember to use the drops regularly, twice a day.
If you normally wear soft contact lenses, please make sure your doctor knows about this.
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About brimonidine eye drops
Typ av medicin | An alpha2-adrenoceptor agonist eye drop |
Används för | To reduce raised eye pressure |
Även kallad | Alphagan® |
Tillgänglig som | Eye drops |
An increase in pressure within your eye can lead to damage to the optic nerve at the back of your eye. When this occurs it is called glaucoma. Glaucoma can lead to a loss of vision if it is not treated. If you have an increased pressure within your eye but without any damage to the optic nerve, this is called ocular hypertension. People with ocular hypertension have an increased risk of later developing glaucoma. Treatment with brimonidine eye drops helps to reduce eye pressure in people with ocular hypertension, and to prevent further eye damage in people with glaucoma.
Brimonidine eye drops are thought to work by reducing the amount of fluid that you make in the front part of your eye (called aqueous humour) and by increasing the drainage of fluid from your eye. These two actions help to lower the pressure within your eye.
Sometimes, more than one type of eye drop is needed to keep the pressure in the eye low. If this is the case for you, you may be asked to use two different eye drops, or you may be given drops which combine more than one type. Brimonidine is available as a combination eye drop with timolol (a beta-blocker) in a brand called Combigan®, and with brinzolamide (a carbonic anhydrase inhibitor) in a brand called Simbrinza®.
Before using brimonidine eye drops
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start using the eye drops, it is important that your doctor knows:
Om du bär mjuka kontaktlinser.
Om du är gravid eller ammar.
If you have a heart condition or blood vessel disorder.
If you have a blood circulation problem (particularly if you have Raynaud's syndrome).
If you feel dizzy when you sit up or stand up quickly.
If you have a depressive illness.
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to use brimonidine eye drops
Tillbaka till innehållTvätta händerna noggrant innan du använder dropparna.
Remove the cap.
Luta huvudet lite bakåt och dra det nedre ögonlocket nedåt för att bilda en ficka.
Hold the bottle upside down near to your eye. Try not to touch your eye as you do this.
Apply enough pressure to the bottle to release one drop into your eye. (Do not use more than one drop - using several drops does not improve your glaucoma but will increase the risk of side-effects.)
Stäng ögat i en eller två minuter och tryck försiktigt på sidan av näsan där ögonvrån möter näsan. Detta hjälper till att förhindra att droppen rinner bort och håller den kvar i ögat.
Repeat the process in your other eye if you have been told to use the drops in both eyes.
Replace the cap.
Få ut det mesta av din behandling
Tillbaka till innehållBefore you start using the eye drops, read the manufacturer's printed information leaflet from the pack. It will give you more information about the eye drops and will provide you with a full list of the side-effects which you may experience from using them.
Use one drop into the eye (or eyes) affected. The drops are used twice each day, 12 hours apart. Your dose will also be printed on the label of the bottle to remind you.
Remember to use the drops at regular intervals and try not to miss any doses. If you do forget, use them as soon as you remember (unless it is nearly time for your next dose, in which case just use the drops when they are next due). Do not 'double up' to make up for a missed dose.
Take care not to touch the tip of the dropper with your eye, fingers, or any other surface. This is to prevent the drops from becoming contaminated.
If you are using any other eye drops, leave 5-10 minutes between applying each one. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and not have the intended effect.
When first put in, eye drops can make your eyes water and may sometimes cause blurred vision. If this happens, it should quickly clear. Make sure you can see clearly again before you drive, or use tools or machines.
Do not wear soft contact lenses unless your doctor has advised you otherwise. This is because bottles of eye drops contain preservatives which can affect soft contact lenses.
Keep your regular appointments with your doctor and eye clinic so that your progress can be checked.
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Can brimonidine eye drops cause problems?
Tillbaka till innehållAlong with their useful effects, eye drops can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with brimonidine. You will find a full list in the manufacturer's information leaflet supplied with the drops. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist for further advice if any of the following continue or become troublesome.
Side-effects of brimonidine eye drops (some of these can be very common affecting more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Dry eye, blurred vision, eye redness, stinging and irritation, sensitivity to light | These symptoms should soon pass, but make sure you can see clearly before driving or before using tools or machines. If this continues or becomes troublesome, speak with your doctor |
Feeling tired, sleepy or dizzy | If this happens, do not drive and do not use tools or machines until the feeling passes |
Huvudvärk | Ask your pharmacist to recommend a suitable painkiller. If the headache continues, speak with your doctor |
Torr mun | Try chewing sugar-free gum, or sucking sugar-free sweets |
Cold-like symptoms, stomach upset, unusual taste | Om något av dessa blir besvärligt, tala med din läkare |
Important: occasionally people can be allergic to eye drops, particularly if the eye drops contain a preservative. If you notice a rash around your eyes, or any swelling or itching, stop using the drops and contact a doctor or pharmacist for advice. Long-term use of preserved eye drops may lead to eye irritation and symptoms of dry eyes. If your eyes or eyelids become red or inflamed after using the drops, contact your doctor for advice.
How to store brimonidine eye drops
Tillbaka till innehållEye drops can be used for four weeks once the bottle has been opened. Even if there is still some solution remaining after this time, throw it away and use a new bottle. This will help to prevent the risk of eye infections.
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
If you buy any medicines check with a pharmacist that they are safe to take with your prescribed medicines.
This preparation is for use in the eyes only. If someone swallows some of it, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vidare läsning och referenser
- Manufacturer's PIL, Alphagan® 0.2% w/v (2 mg/ml) eye drops, solution; AbbVie Ltd, The electronic Medicines Compendium. Dated June 2024.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 26 Nov 2027
26 Nov 2024 | Senaste versionen

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