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Brinzolamide eye drops for glaucoma

Azopt

Brinzolamide eye drops are used to control increased pressure within your eye (glaucoma).

Remember to use the drops regularly - try not to miss any doses.

If you normally wear soft contact lenses, please make sure your doctor knows about this.

At a glance

  • Brinzolamide eye drops reduce high pressure inside your eye.

  • They are used to treat glaucoma and ocular hypertension.

  • You will typically use one drop in the affected eye(s) two or three times daily.

  • Do not wear soft contact lenses unless advised by your doctor.

  • Eye drops can cause temporary blurred vision; do not drive until this clears.

  • If your eye becomes red, painful, or inflamed, contact your doctor.

  • Eye drop bottles should be discarded four weeks after opening.

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About brinzolamide eye drops

Typ av medicin

A carbonic anhydrase inhibitor

Används för

Raised eye pressure, such as in glaucoma

Även kallad

Azopt®
Combination brands: Azarga® (brinzolamide with timolol); Simbrinza® (brinzolamide with brimonidine)

Tillgänglig som

Eye drops

An increase in pressure within your eye can lead to damage to the optic nerve at the back of your eye. When this occurs it is called glaucoma. Glaucoma can lead to a loss of vision if it is not treated. If you have an increased pressure within your eye but without any damage to the optic nerve, this is called ocular hypertension. People with ocular hypertension have an increased risk of later developing glaucoma. Treatment with eye drops such as brinzolamide helps to reduce eye pressure in people with ocular hypertension, and to prevent further eye damage in people with glaucoma.

Brinzolamide works by blocking the action of an enzyme called carbonic anhydrase. Blocking this enzyme reduces the amount of fluid that you make in the front part of your eye (called aqueous humour), and this helps to lower the pressure within your eye.

Sometimes, more than one type of eye drop is needed to keep the pressure in the eye low. If this is the case for you, you may be asked to use two different eye drops, or you may be given drops which combine more than one type. Brinzolamide is available as a combination eye drop with a beta-blocker called timolol (in a brand called Azarga®), and with a medicine called brimonidine (in a brand called Simbrinza®).

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start using the drops it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have any problems with the way your kidneys work or with the way your liver works.

  • Om du bär mjuka kontaktlinser.

  • If you have a condition where your blood acidity is too high, called hyperchloraemic acidosis.

  • If you are taking any medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have ever had a bad reaction to any other eye drops, or to a type of medicine known as a 'sulfonamide'.

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  1. Tvätta händerna noggrant innan du använder dropparna.

  2. Remove the cap.

  3. Tilt your head back a little and pull the lower lid of your eye out to form a pocket.

  4. Hold the bottle upside down near to your eye. Try not to touch your eye as you do this.

  5. Apply enough pressure to the base of the bottle to release one drop into your eye. Only use a second drop if the first drop missed going into your eye.

  6. Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.

  7. Repeat the process in your other eye if you have been told to use the drops in both eyes.

  8. Replace the cap.

  • Before you start using the eye drops, read the manufacturer's printed information leaflet from the pack. It will give you more information about the eye drops and will provide you with a full list of the side-effects which you may experience from using them.

  • Use one drop into the eye (or eyes) affected. The drops are usually used two or three times each day, but your doctor will tell you how many times a day is right for you - your dose will also be printed on the label of the pack. Remember to use the drops at regular intervals and try not to miss any doses.

  • If you forget to use the drops, put them in as soon as you remember, but do not 'double up' to make up for any missed doses.

  • Take care not to touch the tip of the dropper with your eye, fingers, or any other surface. This is to prevent the drops from becoming contaminated.

  • If you are using any other eye drops, leave 5-10 minutes between applying each one. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and not have the intended effect.

  • When first put in, eye drops can make your eyes water and may sometimes cause blurred vision. If this happens, it should quickly clear. Make sure you can see clearly again before you drive and before you use tools or machines.

  • Do not wear soft contact lenses unless your doctor has advised you otherwise. This is because there is a preservative in bottles of eye drops which can affect soft contact lenses.

  • Keep your regular appointments with your doctor and eye clinic so that your progress can be checked.

  • If you are having an operation or any dental treatment, remember to tell the person carrying out the treatment about any medicines you are taking or using.

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Along with their useful effects, eye drops can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with brinzolamide. You will find a full list in the manufacturer's information leaflet supplied with your drops. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common brinzolamide side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Blurred vision, itching or irritation when the drops are first put in

This should quickly ease. If it continues, or if your eye becomes red, painful or inflamed, speak with your doctor as soon as possible

Altered taste

Make sure you press gently on the side of your nose (where the corner of your eye meets your nose) for a minute or so after you have used the drops

Important: Bottles of eye drops contain preservatives which some people can develop an allergic reaction to. If your eye becomes red or inflamed after using the drops, contact your doctor for advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

  • Eye drops in bottles only keep for four weeks once the bottle has been opened, so do not use the drops if the bottle has been open for longer than this. This will help reduce the risk of eye infections.

Viktig information om alla läkemedel

Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.

If you suspect that someone has swallowed this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Vanliga frågor

What is the difference between glaucoma and ocular hypertension?

Glaucoma occurs when increased pressure inside your eye leads to damage to the optic nerve, potentially causing vision loss. Ocular hypertension means you have high eye pressure but no optic nerve damage yet, though it increases your risk of developing glaucoma later.

How does brinzolamide help to reduce eye pressure?

Brinzolamide works by blocking an enzyme called carbonic anhydrase. This action reduces the amount of fluid, known as aqueous humour, produced in the front part of your eye, which in turn lowers the pressure inside your eye.

Can I use brinzolamide eye drops if I am pregnant or breastfeeding?

It is important to inform your doctor if you are pregnant or breastfeeding before you start using brinzolamide eye drops. Your doctor will then be able to advise if it is suitable for you.

What should I do if I forget to use my brinzolamide eye drops?

If you forget to use your drops, put them in as soon as you remember. However, do not 'double up' or use extra drops to make up for any missed doses.

How long should I wait between using brinzolamide and other eye drops?

If you are using other types of eye drops, you should leave 5-10 minutes between applying each one. This allows each drop to be absorbed properly and prevents an overflow of liquid from your eye, which could reduce their intended effect.

Can brinzolamide eye drops affect my ability to drive?

When you first put in eye drops, they can cause your eyes to water and may temporarily blur your vision. If this happens, wait until your vision clears completely before you drive or operate any tools or machinery.

Why do I need to press on the side of my nose after applying the drops?

Pressing gently on the side of your nose where it meets the corner of your eye for a minute or two after applying the drops helps prevent the medication from draining away. This keeps the drop in your eye, allowing it to work more effectively.

How long can I use an opened bottle of brinzolamide eye drops?

Once a bottle of eye drops has been opened, it should only be used for four weeks. After this time, you should not use the drops, even if there is still liquid left, to reduce the risk of eye infections.

Vidare läsning och referenser

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 10 Feb 2027
  • 15 Apr 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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