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Calcipotriol för psoriasis

Dovonex

Calcipotriol is usually applied once or twice each day. Your doctor will tell you which is right for you.

Do not use more than the maximum recommended amount of preparation.

Remember to wash your hands well after using calcipotriol. This will help to prevent accidentally getting it on other areas of your skin, which could cause irritation.

Överblick

  • Calcipotriol is a topical vitamin D analogue used to treat plaque psoriasis.

  • It is available as an ointment, gel, foam, and scalp solution.

  • Calcipotriol works by slowing down the overproduction of skin cells.

  • Do not exceed the maximum recommended amount of calcipotriol per week.

  • You should not use calcipotriol on your face as it can cause irritation.

  • Tell your doctor if you are pregnant, breastfeeding, or have high blood calcium levels.

  • Common side-effects include burning, stinging, redness, itching, and dryness of the skin.

About calcipotriol

Typ av medicin

A topical vitamin D analogue

Används för

Plaque psoriasis in adults and in children aged over 6 years

Även kallad

Calcipotriene (in US);
Dovonex®;
Combination brands: Dovobet®, Dalbecal®, Enstilar®, Wynzora® (calcipotriol with betametason)

Tillgänglig som

Ointment, gel, foam and scalp solution

Calcipotriol is used to treat plaque psoriasis - this is the most common type of psoriasis. It is a condition where red scaly patches called plaques develop on your skin. The most common areas affected are over your elbows and knees, the scalp, and the lower part of your back. The patches may vary in size from time to time and can be itchy. Treatment for psoriasis aims to clear the plaques as much as possible.

Psoriasis is caused by cells in the outer layer of your skin multiplying faster than normal. This causes the older and dead skin cells to build up on the surface of your skin, causing the scaly patches. Calcipotriol works by slowing this overproduction of skin cells which eases the inflamed, scaly areas. It is similar to vitamin D, which is a vitamin essential for healthy skin.

Sometimes calcipotriol is used in combination with a steroid medicine called betametason (as in a brand called Dovobet®). It is not recommended that a steroid be used long-term, so this combination is often used for around a month, followed by treatment with calcipotriol alone.

Before using calcipotriol

To make sure that this is the right treatment for you, before you start using calcipotriol it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have been told you have a form of psoriasis known as erythrodermic or pustular psoriasis. This is because more severe forms of psoriasis like these should only be treated by a skin specialist doctor.

  • If you have been told you have high calcium levels in your blood, or if your body has problems processing calcium.

  • If you are taking any other medicines or using any other skin preparations. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to use calcipotriol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about applying calcipotriol and will provide you with a full list of the side-effects which you could experience from using it.

  • Your doctor will tell you how often to use the preparation you are given but as a guide:

    • Calcipotriol ointment is usually applied once or twice each day. If you have been told to use it twice a day, use it in the morning and in the evening.

    • Calcipotriol ointment which also contains betamethasone (brand name Dovobet® Ointment) should be applied only once a day. It is important that you do not use Dovobet® on areas of your skin which you think might be infected, and that you do not cover any treated areas with a bandage or dressing.

    • Calcipotriol scalp solution should be applied twice each day, in the morning and evening. The solution will quickly dry after it has been applied.

    • Calcipotriol with betamethasone gel (brand name Dovobet® Gel) should be applied once each day. For the best effect, leave it on during the day if you have applied it in the morning, or overnight if you have used it in the evening. It is suitable to be used on patches of psoriasis on your skin and on your scalp. It is important that you do not use Dovobet® on areas of your skin which you think might be infected, and that you do not cover any treated areas with a bandage or dressing.

    • Calcipotriol with betamethasone foam (brand name Enstilar®) should be applied once daily for four weeks. After that it can be used twice each week for long-term prevention. You should leave at least two days between applications.

  • The manufacturer's instructions state that you should not use more than a maximum amount of calcipotriol, as otherwise you may get too much calcium in your blood which can cause side-effects. Do not use more than:

    • 100 g of calcipotriol ointment per week for adults.

    • 75 g of calcipotriol ointment per week for children aged over 12 years.

    • 50 g of calcipotriol ointment per week for children aged between 6 and 12 years.

    • 60 ml of calcipotriol scalp solution per week for adults.

    • 15 g per day of Dovobet® Ointment or Gel for adults.

    • 15 g per day of Ensilar® cutaneous foam for adults

Viktigt: if you are using more than one preparation which contains calcipotriol, the total amount of all products you use should not be more than the amounts stated above.

Få ut det mesta av din behandling

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • You should start to see an improvement in your skin within a week or so and this improvement should continue for several weeks before you feel the full benefit. Continue to apply the preparation regularly for as long as you have been recommended so that you get the full benefit.

  • If you are also using a moisturiser for your skin, use this first and then wait until it has soaked into your skin before you apply calcipotriol.

  • Calcipotriol can cause skin irritation. Because of this, you should not use it on your face.

  • Wash your hands well after using any calcipotriol preparation. This will help to prevent calcipotriol getting on to any areas of your skin which are unaffected by psoriasis, and causing irritation.

  • Your skin may become more sensitive to sunlight than normal while you are using calcipotriol. Try to avoid sitting out in the sun and do not use sunbeds.

Can calcipotriol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with calcipotriol. You will find a full list in the manufacturer's information leaflet supplied with the medicine. The unwanted effects often improve as your body adjusts to the new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common calcipotriol side-effects (these affect more 1 in 10 people)

Vad kan jag göra om jag upplever detta?

A burning or stinging feeling

This should soon pass but if it continues or becomes severe, speak with your doctor

Common calcipotriol side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Skin redness, itching, irritation, tingling, or dryness

These should soon pass but if any continue or become severe, speak with your doctor

Viktigt: there is a risk of fire when creams and ointments are absorbed by fabrics (such as clothing or bedsheets), making them flammable. A spark or flame can easily ignite the fabric. The risk is highest when large amounts of paraffin-based products are applied and absorb into fabrics. However there is also a risk when non-paraffin products are used. Be aware of this fire hazard when repeatedly using large amounts of any skin product. Do not smoke or go near naked flames.

If you experience any other symptoms which you think may be due to the preparation, please speak with your doctor or pharmacist for further advice.

How to store calcipotriol

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.

If you are having an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking.

Denna beredning är endast avsedd för användning på huden. Om någon av misstag sväljer något av det, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

symptomkontroll

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

Can calcipotriol be used on all parts of the body affected by psoriasis?

Calcipotriol can be used on many areas affected by plaque psoriasis, including your elbows, knees, scalp, and lower back. However, it is not recommended for use on the face due to potential skin irritation.

How long will it take to see an improvement in my psoriasis after starting calcipotriol?

You should begin to see an improvement in your skin within about a week of starting calcipotriol. This improvement will continue over several weeks as you experience the full benefits of the treatment.

How should I apply calcipotriol if I also use a moisturiser?

If you are also using a moisturiser for your skin, you should apply the moisturiser first. Wait until it has completely soaked into your skin before applying calcipotriol.

What should I do if I accidentally get calcipotriol on skin areas not affected by psoriasis?

To prevent irritation on unaffected skin, always wash your hands thoroughly after applying any calcipotriol preparation. This helps ensure the medicine only stays on the areas intended for treatment.

What is the fire risk associated with calcipotriol products and other skin creams?

There is a fire risk when creams and ointments, including calcipotriol products and other skin preparations, are absorbed by fabrics like clothing or bedsheets, making them flammable. This risk is higher with large amounts of paraffin-based products, but also exists with non-paraffin products. It is important to be aware of this hazard and avoid smoking or being near naked flames when using such products, especially if they have soaked into fabrics.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 21 Sept 2027
  • 20 Sept 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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