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Nicardipinkapslar

Cardene

Nicardipine is prescribed for high blood pressure, and to prevent angina.

When you first start taking the capsules you may get a headache or feel flushed. These symptoms usually go after a few days.

You can take nicardipine capsules before or after meals.

Överblick

  • Nicardipine is a calcium-channel blocker medicine.

  • It is used to treat high blood pressure or to prevent angina chest pain.

  • It works by relaxing and widening blood vessels to lower blood pressure.

  • Standard capsules are taken three times a day, and modified-release capsules twice daily.

  • Avoid drinking grapefruit juice while taking nicardipine.

  • Common side-effects include headaches, feeling flushed, and dizziness.

  • If you experience worsening chest pain, tell your doctor straightaway.

About nicardipine

Typ av medicin

A calcium-channel blocker

Används för

High blood pressure; to prevent angina

Även kallad

Cardene®

Tillgänglig som

Capsules and injection

Nicardipine belongs to a group of medicines called calcium-channel blockers. It is prescribed to treat högt blodtryck (hypertoni), or to prevent angina chest pain. You will have been prescribed it for one of these reasons.

It works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina chest pain. It does these things by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of your arteries and in your heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax.

In some countries nicardipine is available as a modified-release capsule. This means that the capsules release nicardipine more slowly than the standard capsules. They can be prescribed for people with high blood pressure.

Before taking nicardipine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking nicardipine it is important that your doctor knows:

  • If you have any heart problems (other than angina or high blood pressure), or if you have recently had a heart attack.

  • If you have angina pain when you are resting as well as when you are active.

  • If you have been told you have narrowing of the main blood vessel from your heart (aortic stenosis).

  • Om du är gravid eller ammar.

  • If you have problems with the way your liver works, or problems with the way your kidneys work.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.

How to take nicardipine

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about nicardipine and will provide you with a full list of the side-effects which you may experience from taking the capsules.

  • Standard nicardipine capsules (Cardene®) are taken three times a day. There are two strengths available - 20 mg and 30 mg. You will be prescribed the lower-strength capsule first, and then the higher-strength capsule after a few days if your doctor feels it is necessary.

  • Modified-release capsules are taken twice daily - morning and evening. There are three strengths available - 30 mg, 45 mg and 60 mg. You will be prescribed the lower-strength capsule to begin with and your dose adjusted later if needed.

  • Space out your doses during the day, and try to take them at the same times each day as this will help you to remember to take your doses regularly. Swallow the capsules whole with a drink of water. You can take nicardipine before or after meals.

  • If you forget to take a dose, take it as soon as you remember. If when you remember, it is nearly time for your next dose then take your next dose when it is due but leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • Your doctor will discuss with you the possibility of unwanted side-effects. When you first start taking nicardipine you may experience headaches, feeling flushed, and some dizziness. These effects usually only last for a few days, but if they continue or become troublesome, you should let your doctor know.

  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on nicardipine as it can increase the chance that you experience side-effects, such as feeling dizzy or light-headed.

  • You should not drink grapefruit juice while you are on nicardipine. This is because a chemical in grapefruit juice increases the amount of nicardipine in your blood and this makes side-effects more likely.

  • Nicardipine is a medicine which helps to prevent angina pain from developing, it will not provide you with immediate pain relief if you have an angina attack. Your doctor will give you a different medicine to take for this.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers can reduce the effectiveness of nicardipine.

  • If you need to have an operation or any medical treatment, tell the person carrying out the treatment which medicines you are taking. Nicardipine and some anaesthetics can interact and may cause your blood pressure to drop too low.

  • Treatment with nicardipine is usually long-term unless you experience an adverse effect. Continue to take the capsules unless you are told otherwise by your doctor. If it is necessary for you to stop, your doctor may want you to reduce your dose over a few days, as there is some evidence to suggest that stopping taking nicardipine suddenly can cause some symptoms to return.

Can nicardipine cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with nicardipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common nicardipine side-effects

Vad kan jag göra om jag upplever detta?

Headache, feeling hot or flushed

These may occur when you first start treatment, but usually go away after a few days. If the headache continues discuss the problem with your doctor

Feeling sick (nausea) or being sick (vomiting)

Stick to simple foods - avoid rich or spicy meals

Känner dig yr

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Swollen ankles, being aware of fast heartbeats (palpitations)

Speak with your doctor about these if troublesome

Viktigt: a few people taking nicardipine have experienced worsening of chest pain at the start of treatment or after a dose increase - if this happens to you, you must let your doctor know straightaway.

If you experience any other symptoms which you think may be due to the capsules, you should speak with your doctor or pharmacist for further advice.

How to store nicardipine

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Vanliga frågor

What should I do if I experience worsening chest pain when I start taking nicardipine or after a dose increase?

You must let your doctor know straightaway if you experience worsening chest pain at the beginning of your treatment or after your dose has been increased. This is an important symptom that requires immediate medical attention.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

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