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Colestipol - ett läkemedel som sänker blodfetter

Colestid

Klinisk författares anmärkning Michael Stewart 05/01/2024: Colestid® sachets were discontinued in the United Kingdom in January 2023. At the time of review there are no licensed products containing colestipol available in the UK. Colestipol tablets and sachets may still be available in other countries or as special order products. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.

Take each sachet of colestipol granules mixed into at least 100 ml of liquid or soft food such as fruit juice, skimmed milk, soup, or yoghurt.

Avoid taking any other medicines at the same time as colestipol. Either take your other medicines one hour before colestipol, or wait until 4-6 hours afterwards.

The main side-effect of colestipol is constipation.

Överblick

  • Colestipol is a medicine used to lower high levels of cholesterol and other fats in your blood.

  • It works by preventing bile acids in your digestive system from being reabsorbed by your body.

  • Take colestipol exactly as prescribed by your doctor, usually mixed with water or other liquids/foods.

  • Avoid taking other medicines at the same time as colestipol to prevent issues with absorption.

  • Common side-effects can include constipation and stomach pain.

  • Tell your doctor if you are pregnant, breastfeeding, or taking other medicines before starting colestipol.

About colestipol

Typ av medicin

A bile acid binder (sequestrant)

Används för

Lowering cholesterol and other lipids

Även kallad

Colestid® (Discontinued in UK)

Tillgänglig som

Tablets and sachets of granules

Colestipol is available as sachets of granules which work in the body as a bile acid sequestrant. This means that it binds to bile acids in your digestive system. It prevents the bile acids from being recycled (reabsorbed) into your body. This action can be useful for people who have higher than normal levels of lipids in their blood.

Lipid is another word for fat. Cholesterol is a type of lipid. Lipids are easily stored in your body and serve as a source of energy. They are made naturally in your body from the food you eat. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. By taking colestipol, it prevents your bile acids from being reabsorbed and, as a consequence, your liver has to make more bile acids. It does this by using certain lipids from your blood. This lowers the amount of lipids in your blood and reduces your risk of heart and blood vessel disease.

Before taking colestipol

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colestipol it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take colestipol

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about colestipol and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the sachets exactly as your doctor tells you to. It is usual to be prescribed one sachet to take once or twice each day to begin with. Depending upon your symptoms, your doctor may slowly increase the number of sachets until you are taking up to six sachets daily.

  • The granules from each sachet should be added to at least 100 ml of water. If you prefer, you can also mix colestipol with skimmed milk, soup, fruit juice, yoghurt or fruit smoothies. The granules do not dissolve well and can have a 'bitty' texture. You will notice this less if you mix the granules with soft foods rather than thin liquids, or alternatively if you prepare your dose a little in advance and allow it to stand for a while. Do not take the granules dry or without mixing them into about 100 ml of drink/food first. Colestipol sachets are also available pre-flavoured with orange and vanilla and with an artificial sweetener in a brand called Colestid® Orange.

  • If you forget to take a dose, take it as soon as you remember. Try to take the correct number of sachets each day, but do not take two doses together to make up for a missed dose.

Få ut det mesta av din behandling

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

  • Avoid taking any other medicines at the same time as you take colestipol because it can stop the other medicines from being absorbed by your body. Either take your other medicines at least one hour before you take colestipol, or wait until 4-6 hours after taking colestipol before you take the other medicines. If you have any problems planning when to take your medicines, speak with your doctor or pharmacist for advice.

  • Treatment with colestipol is often long-term. Continue to take it unless you are advised otherwise.

  • Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

  • Your doctor may give you advice about lifestyle changes that could help you get the most out of your treatment. This may include reducing the amount of salt in your diet, stopping smoking, losing weight, reducing the amount of alcohol you drink, and taking regular exercise. Following this advice will help you to reduce your risk of developing heart and blood vessel disease in the future.

  • Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

  • If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take.

Can colestipol cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with colestipol. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common colestipol side-effects (these affect more than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Förstoppning

Try to eat a well-balanced diet and drink several glasses of water each day. If it becomes troublesome, speak with your doctor

Abdominal (tummy) pain or discomfort

Håll dig till enkla måltider - undvik rik eller kryddstark mat

Migraine, headache

Drink plenty of water and ask a pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Common colestipol side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling sick (nausea) or being sick (vomiting), indigestion, bloated feeling, wind (flatulence)

Håll dig till enkla måltider - undvik rik eller kryddstark mat

Bleeding haemorrhoids (piles), blood in your stools

This may be related to constipation. If you notice any blood in your stools you should let your doctor know straightaway

Diarré

Drink plenty of water to replace the fluids lost

Joint or muscle aches and pains, back pain

Ask a pharmacist to recommend a suitable painkiller. If the pain continues, let your doctor know

Skin rash

Ask a pharmacist to recommend a suitable antihistamine. If the problem continues, let your doctor know

Tiredness (fatigue)

If this becomes a problem, let your doctor know

If you experience any other symptoms which you think may be due to your medicine, speak with your doctor or pharmacist for further advice.

How to store colestipol

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

Can I take colestipol with other liquids besides water?

Yes, you can mix colestipol granules with other liquids like skimmed milk, soup, fruit juice, or fruit smoothies. You can also mix them with soft foods like yoghurt. The granules don't dissolve easily, so mixing them with soft foods or preparing your dose in advance and letting it sit can help improve the texture.

How long will I need to take colestipol?

Treatment with colestipol is often long-term. You should continue to take it unless your doctor advises you otherwise.

What should I do if I find the texture of colestipol granules unpleasant?

The granules do not dissolve well and can have a 'bitty' texture. You may find this less noticeable if you mix them with soft foods rather than thin liquids, or if you prepare your dose a little in advance and allow it to stand for a while. Colestipol sachets are also available pre-flavoured with orange and vanilla, and with an artificial sweetener under the brand name Colestid® Orange.

Are there any specific lifestyle changes I should consider while taking colestipol?

Your doctor may recommend lifestyle changes to help you get the most from your treatment and further reduce your risk of heart and blood vessel disease. These might include reducing salt intake, stopping smoking, losing weight, reducing alcohol consumption, and getting regular exercise.

What if I accidentally swallow the granules dry?

You should not take the granules dry or without mixing them into at least 100 ml of drink or food first.

Can colestipol affect my vitamins?

Taking colestipol over a period of time may reduce your body's absorption of fat-soluble vitamins (vitamins A, D, E, and K) and folic acid. Your doctor may advise you to take a supplement containing these vitamins.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

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