Tizanidin för muskelspasmer
Tizagelan
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 9 Jun 2024
Uppfyller patientens redaktionella riktlinjer
- Ladda nerLadda ner
- Dela
- Language
- Diskussion
- Ljudversion
- Lägg till i föredragna källor på Google
When you first start taking tizanidine, your doctor will give you a small dose. Your dose will then be increased at 3- to 4-day intervals until you are on a dose that suits your condition.
Tizanidine can make you feel sleepy or dizzy. It can slow your reactions, so please take care if you are using tools or machines, or if you drive.
Continue to take the tablets unless your doctor tells you otherwise. Do not suddenly stop taking tizanidine tablets.
Överblick
Tizanidine is a muscle relaxant used to treat muscle spasticity in adults.
It helps to relax stiff and painful muscles, for example, due to multiple sclerosis.
Your doctor will gradually increase your dose to find what works best for you.
Common side-effects include drowsiness, dizziness, dry mouth, and feeling light-headed.
Do not drive or operate machinery if you feel drowsy or dizzy.
Do not drink alcohol while taking tizanidine as it can increase side-effects.
Tell your doctor if you experience unexplained sickness, yellow skin/eyes, weight loss, or extreme tiredness.
About tizanidine
Typ av medicin | A muscle relaxant |
Används för | Muscle spasticity in adults |
Även kallad | Tizagelan® |
Tillgänglig som | Tabletter |
Tizanidine belongs to a group of medicines called muscle relaxants. Muscle relaxants are medicines that are used to prevent or reduce muscle spasms and spasticity. Spasticity occurs when muscles contract tightly and become stiff and harder to use. It often causes pain and discomfort.
Tizanidine is used to relieve spasticity which results from long-term conditions such as multipel skleros and following long-term injuries to the head or back. It works on the nerves in your brain and spine to help relax affected muscles.
Before taking tizanidine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking tizanidine it is important that your doctor knows:
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
Om du är gravid eller ammar.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take tizanidine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about tizanidine and will provide you with a full list of the side-effects which you may experience from taking it.
When starting the treatment, your doctor will give you a small dose (usually 2 mg once daily) and will then gradually increase your dose at 3- to 4-day intervals. This allows your doctor to make sure that you have the dose that helps your condition but avoids any unwanted symptoms. Tizanidine tablets have a relatively short time of action, so you will be prescribed several doses to take each day once you are on a maintenance dose.
Swallow the tablet with a drink of water. You can take tizanidine either before or after meals.
Continue to take tizanidine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what your doctor said to you. Once you are established on a regular dose of tizanidine, try to take your doses at the same times of day each day, as this will help you to remember to take them.
If you do forget to take a dose, take it when you remember unless your next dose is about due. If it is nearly time for your next dose then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have some blood tests from time to time to check that your liver is working properly.
Tizanidine can cause drowsiness and may affect your reactions. Be careful this does not put you at risk if you are using any tools or machines, or if you drive.
It is recommended that you do not drink alcohol while you are on tizanidine. This is because the risk of side-effects, such as feeling sleepy and dizzy, is increased.
Continue to take the tablets unless your doctor tells you otherwise - treatment with tizanidine is usually long-term. Suddenly stopping treatment can cause problems, so your doctor will want you to reduce your dose gradually if this becomes necessary.
If you are due to have an operation or dental treatment, please tell the person carrying out the treatment which medicines you are taking.
Can tizanidine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with tizanidine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common tizanidine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling drowsy, dizzy or tired | Om detta händer, kör inte och använd inte verktyg eller maskiner. Drick inte alkohol |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Feeling light-headed, especially when you stand up (due to low blood pressure) | Moving more slowly may help |
A slower heart beat | This is not usually problematic but speak with your doctor if you have any concerns |
Viktigt: a few people have developed problems with their liver whilst taking this medicine. Although your doctor will check for this, you should speak with your doctor as soon as possible if you have any unexplained sickness (nausea or vomiting), yellowing of skin or eyes (jaundice), loss of weight, or feel extremely tired.
If you experience any other symptoms which you think may be due to the tablets, please speak with your doctor or pharmacist for further advice.
How to store tizanidine
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
This medicine is for you. Do not give it to other people even if their condition appears to be the same as yours.
Om du köper några läkemedel, kontrollera med en apotekare att de är lämpliga att ta tillsammans med dina andra läkemedel.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
MHRA - Rapportera biverkningar
Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can I take tizanidine with other medications?
You should always inform your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This is important because some medicines are not suitable to be taken together, or may require extra care.
How will my doctor determine the correct dose of tizanidine for me?
When starting treatment, your doctor will begin with a small dose, usually 2 mg once daily. They will then gradually increase your dose at 3- to 4-day intervals. This careful approach ensures that you receive the most effective dose for your condition while minimising unwanted side-effects.
What should I do if I feel light-headed when standing up after taking tizanidine?
Tizanidine can sometimes cause you to feel light-headed, especially when standing up, due to a drop in blood pressure. If this happens, moving more slowly can be helpful. If it continues to be troublesome, you should speak with your doctor or pharmacist for advice.
What are the common side effects of tizanidine and how can I manage them?
Some common side-effects include feeling drowsy, dizzy, or tired, experiencing a dry mouth, and feeling light-headed when standing up due to low blood pressure. If you feel drowsy or dizzy, you should avoid driving or using tools/machines and not drink alcohol. For a dry mouth, try chewing sugar-free gum or sucking sugar-free sweets. If feeling light-headed, moving more slowly may help. Most of these effects often improve as your body adjusts. If any side effects persist or become bothersome, speak with your doctor or pharmacist.
What should I do if I notice any signs of liver problems while taking tizanidine?
It's important to be aware that a few people on tizanidine have developed liver problems. Although your doctor will monitor this with blood tests, you must speak with your doctor as soon as possible if you experience any unexplained sickness (nausea or vomiting), yellowing of your skin or eyes (jaundice), unexplained weight loss, or feel extremely tired. These could be signs of liver issues.
Vidare läsning och referenser
- Manufacturer's PIL, Tizagelan® 2 mg and 4 mg tablets; G.L Pharma UK Limited. Dated August 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 30 May 2027
9 Jun 2024 | Senaste versionen

Fråga, dela, anslut.
Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.
Anmäl dig till Patientens nyhetsbrev
Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.
Genom att prenumerera accepterar du våra Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.
Mer om läkemedel för nervsystemet
- Aripiprazole
- Atomoxetin för ADHD
- Clozapine
- Co-beneldopa för Parkinsons sjukdom
- Diazepam - en bensodiazepin
- Fluoxetin
- Haloperidol
- Lacosamid för epilepsi
- Lofepramin för depression
- Lorazepam - en bensodiazepin
- Melatonintabletter för sömnlöshet
- Nimodipintabletter
- Orphenadrine
- Pergolid för Parkinsons sjukdom
- Pregabalin
- Primidon för epilepsi
- Sodium valproate for epilepsy
- Tetrabenazintabletter
- Tiagabin för epilepsi
- Trihexyphenidyl