Alimemazine
Alfresed, Itzenal
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 30 Aug 2022
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Alimemazine is used to keep young children calm before an operation, and to ease allergic skin reactions.
It will make you feel sleepy which can affect your ability to drive. If you feel drowsy or sleepy, do not drive and do not use tools or machines.
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About alimemazine
Typ av medicin | A phenothiazine antihistamine |
Används för | Some allergic skin conditions, and as a sedative for young children before an operation |
Även kallad | Trimeprazine (in US); Alfresed®, Itzenal® |
Tillgänglig som | Tabletter och flytande medicin för oral användning |
Alimemazine is used to relieve lumpy and itchy allergic skin reactions called hives (urticaria). It is also used before surgical procedures to help keep young children calm.
Alimemazine, an antihistamine, works by blocking a substance called histamine in the body. In some people, an excess of histamine is produced by exposure to substances such as pollen, pet fur, house dust or insect bites, and this causes allergic skin reactions. By blocking histamine, alimemazine eases the itchiness and lumpiness of these reactions.
When alimemazine is prescribed for a young child who is about to have an operation, it produces a sedative effect which helps the child feel relaxed. Alimemazine is not suitable for children under 2 years of age.
Before taking alimemazine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking alimemazine it is important that your doctor or pharmacist knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have a heart condition or blood vessel disease.
If you have liver, kidney, or prostate problems.
If you have any difficulties passing urine or if you have been constipated for some time.
If you have breathing problems.
If you have any of the following: epilepsy, Parkinson's disease, depression, increased pressure in your eyes (glaucoma), or a condition called myasthenia gravis which causes muscle weakness.
If you have ever had yellowing of your skin or of the whites of your eyes (jaundice) or a blood disorder.
If you have low levels of thyroid hormone (hypothyroidism).
If you have a tumour on your adrenal gland (phaeochromocytoma).
If you have a rare inherited blood disorder called porphyria.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
If you have ever had an allergic reaction to another antihistamine, or to any other medicine.
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How to take alimemazine
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about alimemazine and a full list of side-effects which you may experience from taking it.
Take alimemazine exactly as your doctor tells you to. This information will be printed on the label of the pack you have been supplied with to remind you. The usual recommended doses for allergic skin reactions are:
For adults and children aged 12 years or over: 10 mg taken 2 or 3 times a day (it may be less than this if you are over 65 years of age).
For children 5-11 years of age: 5 mg taken 3 or 4 times daily.
For children 2-4 years of age: 2.5 mg taken 3 or 4 times daily.
If you are giving alimemazine liquid medicine to a child, make sure you follow the dosing instructions on the bottle carefully so that you measure out the correct dose.
You can take alimemazine before or after meals. Some people find it helps to swallow the tablets with a drink of water.
If you forget to take a dose, don't worry, just take the next dose when it is due and then continue as before. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållAlimemazine causes drowsiness. If you feel drowsy or sleepy, do not drive and do not use tools or machines.
Do not drink alcohol while you are on alimemazine as it increases the chance you will feel sleepy.
Alimemazine may cause your skin to become more sensitive than normal to sunlight. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
If you buy any medicines, check with a pharmacist that they are suitable to take with alimemazine. This is because a number of other medicines can interfere with the way alimemazine works or can increase the risk of side-effects.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking alimemazine.
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Can alimemazine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with alimemazine, particularly when it is taken over a period of time. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common alimemazine side-effects | Vad kan jag göra om jag upplever detta? |
Feeling sleepy or dizzy, blurred vision | If this happens, do not drive and do not use tools or machines. You may feel light-headed, particularly when you first start taking this medicine. Getting up more slowly until you are aware how you react should help |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Huvudvärk | Ask your doctor or pharmacist to recommend a suitable painkiller |
Stomach upset | Stick to simple meals |
Feeling shaky or restless, unusual or uncontrollable muscle movements | Speak with your doctor as soon as possible |
Sleeping problems, mood changes, stuffy nose, changes in sexual ability, breast changes or tenderness, menstrual problems, fast heartbeat, constipation, difficulty passing urine, rash | Discuss these with your doctor if any become troublesome |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store alimemazine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Om du köper några mediciner, kontrollera med en apotekare att de är säkra att ta tillsammans med dina andra mediciner.
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Alimemazine Tartrate 10 mg Film-coated Tablets; Zentiva, The electronic Medicines Compendium. Dated January 2021.
- Manufacturer's PIL, Alimemazine Tartrate 7.5 mg/5 ml Syrup; Zentiva, The electronic Medicines Compendium. Dated September 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 27 Feb 2027
30 Aug 2022 | Senaste versionen

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