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Bisoprolol - a beta-blocker

Cardicor

Treatment with bisoprolol is usually long-term. Continue to take the tablets regularly unless you are told otherwise.

There are several different strengths of tablet. If your tablets look unexpectedly different from before, ask your pharmacist to check them for you.

The most common side effects of bisoprolol are feeling tired, cold fingers or toes, headache, and stomach upset.

Clinical author's note: Michael Stewart 15/11/2018: Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other medicines used to treat high blood pressure. It may be available on its own in other countries. For more information see the warning below in 'can this medicine cause problems?' or view the MHRA Alert.

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About bisoprolol

Typ av medicin

A beta-adrenoceptor blocking medicine (often referred to as a beta-blocker)

Används för

High blood pressure, angina, heart failure

Also called (UK)

Cardicor®

Also called (USA)

Ziac® (bisoprolol with hydrochlorothiazide)

Tillgänglig som

Tabletter

Bisoprolol is a type of beta-blocker used to treat high blood pressure, chest pain (angina), and heart failure.

Bisoprolol works on the heart and blood vessels. It does this by blocking tiny areas (called beta-adrenergic receptors) where messages sent by some nerves are received by your heart and blood vessels. As a result, your heart beats more slowly and with less force. The pressure of blood within your blood vessels is reduced and it is easier for your heart to pump blood around your body.

These actions are of benefit if you have high blood pressure (hypertension), or if you have heart failure which is a condition where your heart is not working as well as it should. Because your heart is using less energy, it also helps to reduce chest pain if you have angina.

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The most common side effects of bisoprolol are:

  • Feeling dizzy or lightheaded.

  • Feeling sleepy or tired.

  • Känna sig illamående (illamående).

  • Kräkningar.

  • Diarré.

  • Förstoppning.

  • Headache.

  • Cold fingers and toes.

  • Disturbed sleep.

  • Slow heartbeat.

You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common bisoprolol side effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling dizzy, sleepy, tired or light-headed

Getting up and moving more slowly may help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. This usually improves after the first week or two, but if it continues, speak with your doctor. If affected, do not drive and do not use tools or machines until you feel better

Feeling sick or being sick, diarrhoea or constipation

Stick to simple foods and drink plenty of water

Huvudvärk

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, speak with your doctor

Cold fingers or toes, disturbed sleep, slow heartbeat

Speak with your doctor if any of these become troublesome

If you are also taking hydrochlorothiazide in combination with this medicine:

  • Studies have suggested that taking higher doses of hydrochlorothiazide for long periods of time may increase the risk of certain skin cancers.

  • Tell your doctor if you have ever been treated for skin cancer before.

  • Tell your doctor about any new or changed moles or worrying marks on your skin.

  • Use a sunscreen in strong sunlight. Do not use sunbeds.

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

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Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking bisoprolol it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have asthma or any other breathing disorder.

  • Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

  • If you have low blood pressure or poor circulation.

  • If you have diabetes.

  • If you have a skin problem called psoriasis.

  • Om du har ett tillstånd som orsakar muskelsvaghet, kallat myasthenia gravis.

  • If you have been told you have a slow heartbeat or heart block (a slow and irregular heartbeat).

  • If you have been told you have chest pain caused by spasms of your heart's blood vessels, called Prinzmetal's angina.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • If you have ever had an allergic reaction to a medicine, or if you have ever had any other serious allergic reaction.

  • Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about bisoprolol and will provide you with a full list of side effects which you may experience from taking it.

  • Take bisoprolol exactly as your doctor tells you to. The usual dose is one tablet each day, although the strength of your tablet will depend upon the reason why you are taking it.

  • If you are taking it for heart failure, you will be started on a low-strength tablet (1.25 mg) and then you will be prescribed a different strength of tablet each week for the first few weeks. This is so your doctor can increase your dose gradually.

    • Your dose and the strength of the tablets will be on the label of the pack. There are several strengths of tablet available: 1.25 mg, 2.5 mg, 3.75 mg, 5 mg, 7.5 mg and 10 mg.

    • Each time you collect a fresh supply of tablets it is a good idea to check to make sure you receive the strength you are expecting. If you have any questions, please ask your pharmacist to advise you.

  • You can take the tablets either with or without food, but try to take your doses at the same time of day each day as this will help you to remember to take bisoprolol regularly. The tablets are best swallowed in the morning with a drink of water.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

  • Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

  • If you are due to have an operation or dental treatment, it is important to tell the person carrying out the treatment that you are taking a beta-blocker. This is particularly important if you are likely to be given an anaesthetic.

  • If you drink alcohol, ask your doctor for advice about taking bisoprolol and alcohol. Alcohol will add to the blood pressure-lowering effect of bisoprolol which will make you feel dizzy and so may not be recommended for you.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with bisoprolol. Some medicines may not be (including some anti-inflammatory painkillers, and cold or flu remedies).

  • Your doctor may give you dietary and lifestyle advice about eating a healthy diet, not smoking, and taking regular exercise. If so, it is important that you follow the advice you are given.

  • If you have diabetes, bisoprolol can block the symptoms of low blood sugar. Your doctor will advise you about this.

  • Treatment with bisoprolol is usually long-term. Continue to take the tablets unless your doctor tells you to stop. Stopping treatment suddenly can cause problems in some people, so your doctor may want you to reduce your dose gradually if this becomes necessary.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

Can you take apixaban and bisoprolol together?

Yes, apixaban and bisoprolol are sometimes prescribed together, especially for people with heart conditions such as atrial fibrillation. Apixaban helps prevent blood clots, while bisoprolol lowers blood pressure and reduces strain on the heart.

Why am I so tired on bisoprolol?

Feeling tired is a common side effect of bisoprolol. The medicine slows your heart rate and reduces how hard your heart has to work, which can sometimes leave you feeling fatigued, especially when you first start taking it. For most people this improves over time.

What can you not take with bisoprolol?

Bisoprolol can interact with other heart medicines, some antidepressants, asthma inhalers, and decongestants. Always check with your doctor or pharmacist before taking bisoprolol.

Is bisoprolol a blood thinner?

Bisoprolol is not a blood thinner – it’s a beta-blocker used to slow heart rate and lower blood pressure.

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