Clobazam for epilepsy

About clobazam for epilepsy

Clobazam is used alongside other medicines to treat epileptic disease and seizures. It can be taken both by adults and by older children.

If you have epilepsy, it means that you have had more than one unexplained fit (seizure). A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable anti-epileptic medication.

Clobazam controls the symptoms of seizures by stabilising the electrical activity of your brain, which prevents the seizures from occurring. It also relaxes muscles that stiffen (contract) during a seizure. This means that the numbers of seizures are reduced, and those that do occur, are less severe.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking clobazam it is important that your doctor knows:

• Om du är gravid, försöker bli gravid eller ammar.

• If you have any breathing problems.

• Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.

• If you have a mental health problem. This includes conditions such as psychosis, depression, obsessive conditions, phobias and personality disorders.

• If you have ever had a drug or alcohol addiction.

• If you have a condition causing severe muscle weakness, called myasthenia gravis.

• If you have been told you have spinal or cerebellar ataxia. These are conditions where you have difficulty controlling your movements - you may become shaky and unsteady, have slurred speech or rapid eye movements.

• Om du någonsin har haft en allergisk reaktion mot en medicin.

• Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about clobazam, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take clobazam exactly as your doctor tells you to - the dose will be individualised to suit your needs. You will be advised to take a small dose when you first start taking it, and then to increase your dose over a few weeks as your body gets used to it. Your doctor or pharmacist will explain this to you, and the directions will also be printed on the label of the pack to remind you about what the doctor said to you.

• Clobazam is usually taken as a once-daily dose at bedtime, although as your dose increases you may be asked to take it divided into two smaller doses. Try to take it at the same time(s) each day, as this will help you to remember to take your doses regularly.

• You can take clobazam either with or without food. Swallow the tablet(s) with a drink of water. If you have been given liquid medicine, shake the bottle gently before measuring out a dose.

• If you forget to take a dose, take it as soon as you remember. Try to take the correct number of doses each day, but do not take two doses together to make up for a forgotten dose.

• Clobazam is available as tablets and as liquid medicine. Your treatment could be affected by switching between different forms and brands of the medicine. If this is the case for you, each time you collect a new supply, check the label to make sure it is the same as you have had before or ask your pharmacist to check it out for you.

• Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.

• When you first start a new treatment for epilepsy there may be a change in the number or type of seizures you experience. Your doctor will advise you about this.

• Clobazam can make you feel sleepy, especially when you first start treatment. Do not drink alcohol while you are on clobazam as it will increase the likelihood that you experience this side-effect.

• Products containing cannabidiol, or CBD, can also make you more likely to feel sleepy when taking clobazam. You should avoid using any supplements or non-medicinal products containing CBD.

• While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.

• People with epilepsy must stop driving at first. Your doctor will advise you about if and when it may be possible for you to start driving again. This will usually be after a year free of seizures. If you are permitted to drive, please be aware that clobazam is likely to affect your reactions and ability to drive. It is an offence to drive while your reactions are impaired. Please also be aware that the effects of clobazam can last into the following day. Even if your driving ability is not impaired, should you drive, you are advised to carry with you some evidence that the medicine has been prescribed for you - a repeat prescription form or a patient information leaflet from the pack is generally considered suitable.

• Taking clobazam over a period of time can make you become tolerant to it. If this happens, it will not be as effective for you as it once was. If you think this is happening to you, please discuss it with your doctor.

• Taking benzodiazepines like clobazam can lead to the development of dependence, in which your body comes to rely on the medicine. If you are concerned about this, you should discuss it with your doctor.

• Many anti-epileptic medicines can harm an unborn child. If you are a woman, make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you want to have a family, discuss this with your doctor so that you can be given advice from a specialist before you become pregnant.

• If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.

• You need to take clobazam regularly every day. Do not stop taking it until your doctor tells you to stop. Stopping treatment suddenly can cause problems and your doctor will want you to reduce your dose gradually when this becomes necessary.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with clobazam. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.

• Förvara alla läkemedel utom räckhåll och synhåll för barn.

• Förvara på en sval, torr plats, borta från direkt värme och ljus.

• Once a bottle of Tapclob® or Perizam® Oral Suspension has been opened it will keep for 28 days. Zacco® Oral suspension will keep for 60 days after first opening. After this time, make sure you have a fresh supply of medicine.