Asenapine tablets
Sycrest
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 17 Apr 2023
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The usual dose is one tablet (5 mg or 10 mg), taken in the morning and evening. Place the tablet under your tongue and allow it dissolve there. Do not eat or drink for 10 minutes afterwards.
The most common side-effects are drowsiness and anxiety.
Keep your regular appointment with your doctor so your progress can be checked.
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About asenapine tablets
Typ av medicin | An antipsychotic medicine |
Används för | Episodes of mania associated with bipolar disorder in adults |
Även kallad | Sycrest® |
Tillgänglig som | Sublingual (dissolve under the tongue) tablets |
Bipolär sjukdom is a long-term condition where you have periods of lows (depression) and periods of highs (mania or hypomania).
Asenapine will have been given to you to treat episodes of mania caused by bipolar disorder. It is not known exactly how it works, but it is thought to adjust the levels of certain chemicals in your brain which affect your mood. This decreases the intensity and frequency of the manic episodes you experience.
Before taking asenapine tablets
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking asenapine, it is important that your doctor knows:
Om du är gravid eller ammar.
If you have a heart condition or blood vessel disease.
If you have liver, kidney, or prostate problems.
If you have breathing problems.
If you have any of the following: epilepsy, demens, Parkinson's disease, depression, raised pressure in your eye (glaucoma), or a condition causing muscle weakness, known as myasthenia gravis.
If you have a blood disorder.
If you have ever had yellowing of your skin and the whites of your eyes (gulsot).
If you have a condition called phaeochromocytoma, a tumour on your adrenal gland.
If you have ever had an allergic reaction to any medicine.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
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How to take asenapine tablets
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about asenapine tablets and a full list of side-effects which you may experience from taking them.
Take asenapine tablets exactly as your doctor tells you to. The usual dose is one tablet twice daily, with the doses taken in the morning and the evening. There are two strengths of tablet - 5 mg and 10 mg. You may be started on one strength of the tablet and then switched to the other - this will depend upon how your symptoms respond to the medicine.
Peel back the coloured tab covering the blister packaging and remove the tablet (make sure your hands are dry as you do this). Place the tablet under your tongue and allow it to dissolve there - this will only take a few seconds. In order to make sure all the medicine has been absorbed, do not eat or drink anything for 10 minutes afterwards.
If you are also taking other medicines at the same times of day as asenapine, take your other medicines first. Asenapine tablets should be taken last.
If you forget to take a dose, take it as soon as you remember, unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållYour treatment will require careful monitoring to make sure that you get the best possible benefit from asenapine. Keep your regular doctor's appointments so that your progress can be checked. You may need to have some tests from time to time.
Treatment with asenapine is usually long-term unless you experience an adverse effect. Keep taking the tablets until your doctor tells you otherwise. Stopping suddenly can cause problems and your doctor will want you to reduce your dose very gradually if this becomes necessary.
Asenapine may cause your skin to become more sensitive to sunlight than normal. Use a sunscreen that protects against UVA light and has a sun protection factor (SPF) of at least 15, especially in strong sunlight or until you know how your skin reacts. Do not use sunbeds.
If you drink alcohol, ask your doctor for advice about drinking while you are on asenapine. Alcohol will increase the chance that you experience side-effects and may not be recommended for you.
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as asenapine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
If you are having any dental treatment or an operation, tell the person carrying out the treatment which medicines you are taking. This is important because asenapine may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are safe to take with asenapine.
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Can asenapine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with asenapine tablets. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common asenapine side-effects | Vad kan jag göra om jag upplever detta? |
Feeling dizzy, or light-headed, feeling sick (nausea) | This should pass as your body adjusts; in the meantime, try getting up more slowly and sticking to simple foods |
Feeling tired, or sleepy | Do not drive and do not use tools or machines if this happens. Do not drink alcohol |
Anxiety, increased appetite and weight, unusual movements, shaking, feeling weak, changes in the way things taste or feel in your mouth, producing too much saliva | Discuss these with your doctor if any become troublesome |
Viktigt: if you experience any muscle stiffness, with a high temperature, confusion, a fast heartbeat and sweating, contact your doctor immediately. These may be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Viktigt: if you develop any abnormal face or body movements, or feel very restless, speak with your doctor about this as soon as possible.
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store asenapine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Sycrest® 5 mg and 10 mg Sublingual Tablets; Organon Pharma (UK) Ltd, The electronic Medicines Compendium. Dated March 2021.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 15 Oct 2027
17 Apr 2023 | Senaste versionen
15 Jan 2014 | Ursprungligen publicerad
Författad av:
Helen Allen, MPharm

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