Fluoxetin
Olena, Prozac, Prozep
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 30 Aug 2023
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Try to take fluoxetine at the same time each day.
It may take up to four weeks after starting this treatment before you feel the full benefit. Do not stop taking it, even if you feel that it is not helping.
Common side effects of fluoxetine include feeling sick (nausea), diarrhoea, headaches, dry mouth, feeling dizzy, tired or weak, and difficulty sleeping.
Tell your doctor if you feel that you are not getting any better, or if you experience any troublesome side effects.
Överblick
Fluoxetine is an antidepressant of the SSRI type.
It is used to treat depression, bulimia nervosa, and obsessive-compulsive disorder (OCD).
Common side effects include feeling sick, indigestion, headache, and mood changes.
It can take 4-6 weeks to feel the full benefit of fluoxetine.
Do not stop taking fluoxetine suddenly; your doctor will advise on reducing the dose gradually.
If you have thoughts of harming yourself, tell your doctor straightaway.
Seek urgent medical help if you suspect an overdose or allergic reaction.
About fluoxetine
Typ av medicin | A selective serotonin reuptake inhibitor (SSRI) antidepressant |
Används för | Depression, bulimia nervosa, and obsessive-compulsive disorder (OCD) |
Även kallad | Olena®; Prozac®; Prozep® |
Tillgänglig som | Capsules, soluble (dispersible) tablets and oral liquid medicine |
What is fluoxetine used for?
Fluoxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It is used to treat depression, bulimia nervosa, and obsessive-compulsive disorder (OCD).
How does fluoxetine work?
Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine increase the amount of circulating serotonin available in your brain. Altering the balance of the chemicals in the brain can help improve symptoms of depression, eating disorders like bulimia, and OCD.
Depression can develop for no apparent reason, or it can be triggered by a life event such as a relationship problem, a bereavement, or an illness. Bulimia nervosa is an eating disorder. People with bulimia nervosa have episodes of binge eating which they counteract by making themselves sick. Tvångssyndrom (OCD) is a condition where you have recurring and persistent ideas that make you do repetitive actions.
Side effects of fluoxetine
The most common side effects of fluoxetine are:
Illamående.
Kräkningar.
Diarré.
Indigestion.
Torr mun.
Headache..
Feeling more anxious, nervous, or agitated
Feeling restless or shaky.
Feeling dizzy, tired or weak.
Blurred vision.
Trouble sleeping.
Reduced sexual drive (libido).
Yawning.
Svettas.
Du hittar en fullständig lista i tillverkarens informationsblad som medföljer din medicin. De oönskade effekterna förbättras ofta när din kropp anpassar sig till den nya medicinen, men tala med din läkare eller apotekare om något av följande fortsätter eller blir besvärligt.
How to manage fluoxetine side effects
Common fluoxetine side effects | Vad kan jag göra om jag upplever detta? |
Feeling sick or being sick, indigestion, diarrhoea | Håll dig till enkel mat |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Mood changes such as feeling anxious, nervous, agitated or forgetful. Feeling restless or shaky | These usually settle within a few days. If any become troublesome or severe, speak with your doctor |
Feeling dizzy, tired or weak. Blurred vision | If this happens, do not drive and do not use tools or machines until you feel better |
Flushing, sweating, difficulty sleeping, lack of appetite, loss of weight, aches and pains, reduced sexual drive or ability, yawning, a feeling that your heart is pounding (palpitations), itching, changes in taste | Om något av dessa blir besvärligt, tala med din läkare |
Viktigt: a few people taking fluoxetine have developed an allergic-type reaction. You should contact your doctor straightaway if you develop any swelling around your face, any difficulties breathing, or a severe rash.
On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking more than one medicine with this effect. Seek medical attention if you develop any combination of the following:
Stiff muscles or 'jerky' movements.
Unusually fast heartbeat.
High temperature (fever), feeling sick (nausea) or being sick (vomiting), diarrhoea.
Feeling delirious or seeing visions (hallucinating).
If you experience any other symptoms that you think may be due to this medicine, speak with your doctor or pharmacist for further advice.
Who should not take fluoxetine?
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking fluoxetine it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your liver works.
Om du har en hjärtsjukdom.
If you have epilepsy.
If you have high blood sugar levels (diabetes mellitus).
If you have an eye problem called glaucoma.
If you have ever had a bleeding disorder.
If you have ever had abnormally 'high' moods, called mania.
If you are being treated with electroconvulsive therapy (ECT).
Om du någonsin har haft en allergisk reaktion mot en medicin.
If you have taken an antidepressant known as a monoamine-oxidase inhibitor (MAOI) within the previous two weeks.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take fluoxetine
Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about fluoxetine and will provide you with a full list of the side effects which you may experience from taking it.
Take fluoxetine exactly as your doctor tells you to - the directions will be printed on the label of the pack to remind you of what your doctor said.
As a guide, if you are being treated for depression or OCD, it is usual to be prescribed 20 mg (one capsule or 5 ml liquid medicine) as a once-daily dose. Your dose may later be increased.
For people being treated for bulimia, the usual daily dose is 60 mg (three capsules or 15 ml liquid medicine).
You can take fluoxetine before or after food. If you have been given capsules, swallow them whole with a drink of water - do not chew or open the capsules.
If you have difficulty swallowing capsules, let your doctor know, as you could be prescribed liquid medicine or soluble tablets to take instead.
Try to take your doses at the same time of day, each day.
If you have been given soluble (dispersible) tablets, they can be swallowed whole with a drink of water or dissolved in half a glass of water before taking. Do not crush or chew the tablets.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
You may feel that fluoxetine is not working for you straightaway. It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it, even if you feel it is not helping.
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
While you are taking fluoxetine, you may have thoughts about harming yourself or ending your life. These thoughts may also be associated with your condition. It is very important that you tell your doctor about this if it happens.
Do not stop taking fluoxetine unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
You should expect that a course of treatment will last for several months. This is normal and helps to prevent your symptoms from recurring.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on fluoxetine.
If you have diabetes, you may need to check your blood glucose more frequently, as fluoxetine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
If you buy any medicines, check with a pharmacist that they are safe to take with fluoxetine. This is because several medicines which are available from general retail outlets can interfere with this treatment.
In particular, do not take the herbal remedy St John's wort, and ask for advice before buying any anti-inflammatory painkillers.
A few people taking fluoxetine find that their skin is more sensitive to sunlight than normal. Until you know how your skin reacts, use a sun cream with a high sun protection factor (SPF) in strong sunlight.
There are several types of antidepressants and they differ in their possible side effects. If you find that fluoxetine does not suit you then let your doctor know, as another may be found that will.
How to store fluoxetine
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
The oral liquid medicine usually lasts for one month after first opening. After this time make sure you have a fresh supply.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.
Vanliga frågor
Can you drink alcohol on fluoxetine?
You should avoid or limit alcohol when taking fluoxetine, as it can worsen side effects and affect mood. However, an occasional small drink is unlikely to cause serious harm.
Is fluoxetine used more for anxiety or depression?
Fluoxetine is used for both depression and some anxiety disorders, such as obsessive compulsive disorder (OCD). Your doctor will decide if it’s suitable based on your symptoms.
Can you overdose on fluoxetine?
Yes, it’s possible to overdose on fluoxetine. Taking more than the prescribed dose can cause serious side effects such as nausea, tremors, rapid heartbeat or, in severe cases, seizures. Seek urgent medical help if you think you or someone else may have taken too much.
Does fluoxetine make you gain weight?
Fluoxetine can affect weight. Some people may notice slight weight gain, others may lose weight, and many experience no change at all. Changes can be linked to appetite, lifestyle, and how the medication affects mood.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can fluoxetine capsules be opened and sprinkled?
No, fluoxetine capsules should be swallowed whole with a drink of water. Do not chew or open the capsules. If you have difficulty swallowing capsules, you should speak to your doctor who may be able to prescribe a liquid medicine or soluble tablets instead.
Does fluoxetine make you tired?
Yes, feeling dizzy, tired, or weak are common side effects of fluoxetine. If you experience these effects, you should avoid driving or using tools and machines until you feel better.
Is it safe to take 60 mg of fluoxetine?
The typical daily dose for depression or OCD is 20 mg, though your doctor might increase it. For bulimia, the usual daily dose is 60 mg. Always take fluoxetine exactly as your doctor prescribes, as the correct dosage depends on your condition and individual needs.
How long does fluoxetine take to work?
You may not feel the effects of fluoxetine straight away. It can take one to two weeks for the treatment to start building up, and four to six weeks before you feel its full benefit. It's important to continue taking it as prescribed, even if you don't feel immediate improvement.
Does fluoxetine treat anxiety?
Fluoxetine is used to treat depression, bulimia nervosa, and obsessive-compulsive disorder (OCD). OCD is a type of anxiety disorder. The article does not state that it treats all types of anxiety directly, but it does address OCD.
Can I take other medicines with fluoxetine?
When taking fluoxetine, it's important to check with a pharmacist before taking any other medicines, including those available without a prescription, as well as herbal and complementary medicines. Specifically, you should not take the herbal remedy St John's wort, and should ask for advice before buying any anti-inflammatory painkillers.
What should I do if I have thoughts of harming myself while on fluoxetine?
If you experience thoughts about harming yourself or ending your life while taking fluoxetine, it is very important to tell your doctor about this immediately. These thoughts can be associated with your condition, and your doctor needs to be aware of them.
Vidare läsning och referenser
- Manufacturer's PIL, Fluoxetine Capsules 20 mg; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated December 2020.
- Manufacturer's PIL, Fluoxetine 20 mg/5 ml oral solution; Pinewood Healthcare, The electronic Medicines Compendium. Dated November 2020.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensentenVisa fullständig biografi

Dr Colin Tidy, MRCGP
Allmänläkare, Medicinsk Författare
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy är en NHS-läkare, baserad i Oxfordshire.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 29 Aug 2026
30 Aug 2023 | Senaste versionen

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