Xipamide tablets
Diurexan
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 2 Mar 2025
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Xipamide is a 'water tablet' (diuretic).
It is best taken in the morning.
Any side-effects are usually mild, but may include feeling sick (nausea) or dizzy.
At a glance
Xipamide is a diuretic medicine, also known as a 'water tablet'.
It is used to treat high blood pressure and fluid retention.
Take xipamide exactly as your doctor tells you, usually once a day in the morning.
Your doctor may monitor your blood salt levels with blood tests.
Feeling sick or dizzy are possible side-effects.
Tell your doctor if you feel constantly thirsty, have a dry mouth, or dry skin.
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About xipamide
Typ av medicin | Diuretic |
Används för | High blood pressure and fluid retention |
Även kallad | Diurexan® |
Tillgänglig som | Tabletter |
Xipamide belongs to a group of medicines called diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water tablets'. Diuretics are a common treatment for högt blodtryck (hypertension). They are also used to clear fluid from your body in conditions where your body is retaining too much fluid (oedema).
Before taking xipamide
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking xipamide it is important that your doctor or pharmacist knows:
Om du är gravid eller ammar.
If you have kidney or liver problems.
If you have narrowing of the arteries.
If you have gout, diabetes, or an inflammatory condition called systemic lupus erythematosus (SLE). These conditions may be made worse by diuretics.
If you have been told by a doctor that you have low sodium or potassium levels in your blood, or high calcium levels in your blood.
If you have a problem with your adrenal glands, called Addisons sjukdom.
If you have a rare inherited blood disorder called porphyria.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take xipamide
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about xipamide and a full list of side-effects which you may experience from taking it.
Take xipamide exactly as your doctor has told you. The usual dose is one tablet daily, although occasionally up to four tablets daily may be needed for a short while in some people. Your doctor is likely to recommend that you take your dose in the morning. This is so it works during the day and your sleep is not disturbed by you needing to get up to go to the toilet.
Swallow the tablet with a drink of water. You can take it before or after your meals.
If you forget to take a tablet, take it as soon as you remember. However, if it is after 6 pm in the evening, you should skip the forgotten dose and continue as usual the next day. Do not take two doses at the same time to make up for a missed dose.
Få ut det mesta av din behandling
Tillbaka till innehållTreatment for high blood pressure is usually long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems, so it is important that you continue to take these tablets regularly to help reduce the risk of this.
Try to keep your regular appointments with your doctor. This is so your doctor can monitor your blood pressure and check on your progress.
The salt balance in your blood may be upset by xipamide and your doctor may want you to have a blood test from time to time to check for this.
You may be given some lifestyle or dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet and taking some regular exercise. Following this advice will also help to reduce the risk of damage to your heart and blood vessels.
If you are taking xipamide tablets to reduce fluid retention in your legs, regular movements, raising your legs and using support stockings will also help. Talk with your doctor or pharmacist for advice.
Diuretics like xipamide help you to lose water. Occasionally you may lose too much and become lacking in fluid in the body (dehydrated). Let your doctor know if you feel constantly thirsty, your mouth is dry, or your skin looks and feels dry.
Speak with your doctor about how much water to drink each day whilst taking a diuretic; it may depend on your health and body weight.
Drinking alcohol while you are on xipamide may make you feel dizzy. Alcohol can also act as a diuretic and make you dehydrated. Ask for your doctor's advice about whether you should avoid alcohol.
If you buy any medicines, check with a pharmacist that they are suitable to take alongside xipamide.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
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Can xipamide cause problems?
Tillbaka till innehållFörutom sina nyttiga effekter kan de flesta läkemedel orsaka oönskade biverkningar, även om inte alla upplever dem. Dessa förbättras vanligtvis när din kropp anpassar sig till det nya läkemedlet, men tala med din läkare eller apotekare om någon av följande biverkningar fortsätter eller blir besvärliga.
Possible xipamide side-effects | Vad kan jag göra om jag upplever detta? |
Feeling sick (nausea), stomach upset | Stick to simple foods - avoid rich or spicy meals |
Feeling a little dizzy, particularly when you stand up (due to low blood pressure) | Getting up and moving more slowly should help. If you begin to feel dizzy, sit for a few minutes before you stand up again slowly |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store xipamide
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Why do I need to take xipamide every day even if I feel well?
High blood pressure often doesn't make you feel unwell, but if it's not treated, it can cause serious problems for your heart and blood vessels over time. Taking these tablets regularly helps reduce the risk of a heart attack, stroke, or kidney damage, so it's important to continue your treatment as prescribed.
What should I do if I forget to take my xipamide tablet?
If you forget a dose, take it as soon as you remember. However, if it's already after 6 pm, you should skip that forgotten dose and just take your next tablet at the usual time the following day. Never take two doses at once to make up for a missed tablet.
Can I drink alcohol while taking xipamide?
Drinking alcohol with xipamide might make you feel dizzy. Also, alcohol can act like a diuretic itself and could lead to dehydration. It's best to talk to your doctor about whether you should avoid alcohol while on this medication.
How will my doctor check if the xipamide is working and if it's causing any problems?
Your doctor will want you to attend regular appointments to monitor your blood pressure and check on your progress. They may also arrange for you to have blood tests from time to time to check the salt balance in your blood, as xipamide can affect this.
What are the signs that I might be losing too much fluid while on xipamide?
Diuretics help you lose water, but sometimes you might lose too much, which can lead to dehydration. If you notice you're constantly thirsty, your mouth feels dry, or your skin looks and feels dry, you should let your doctor know.
Can I take other medications, including over-the-counter remedies, with xipamide?
It's important to tell your doctor or pharmacist about all other medicines you are taking, including any bought without a prescription, as well as herbal or complementary medicines. If you buy any new medicines, always check with a pharmacist to make sure they are suitable to take alongside xipamide.
Does xipamide interact with any existing health conditions?
Yes, some conditions could be made worse by diuretics like xipamide. It's important to tell your doctor if you have gout, diabetes, or systemic lupus erythematosus (SLE) as these may need extra care. Also mention kidney or liver problems, narrowing arteries, low or high blood mineral levels, Addison's disease, or porphyria, as these can affect how you take xipamide.
Vidare läsning och referenser
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 1 Mar 2028
2 Mar 2025 | Senaste versionen

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