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Gemfibrozil för hyperlipidemi

Lopid

Gemfibrozil reduces fat (lipid) levels. Take your doses about half an hour before a meal.

Some lifestyle changes will also help to reduce your lipid level - eat healthy food, stop smoking, increase the exercise you take, and reduce the amount of salt in your diet.

The most common side-effect is indigestion. If you develop any unusual aches and pains in your muscles, contact your doctor for advice.

Överblick

  • Gemfibrozil is a lipid-regulating medicine used to treat high levels of fats in the blood (hyperlipidaemia).

  • It helps prevent heart and circulation problems by lowering levels of lipids, especially triglycerides.

  • Take gemfibrozil ½-1 hour before a meal, usually before breakfast and the evening meal.

  • Tell your doctor if you have liver, kidney, or gallbladder problems, or an underactive thyroid.

  • You will need regular blood tests to check your progress.

  • Muscle aches or pains, particularly in your legs, can be a serious side-effect.

About gemfibrozil

Typ av medicin

A lipid-regulating medicine commonly known as a fibrate

Används för

Hyperlipidaemia (adults)

Även kallad

Lopid®

Tillgänglig som

Tablets (600 mg) and capsules (300 mg)

Lipid is another word for fat. Cholesterol and triglycerides are types of lipid. When the concentration of lipids in your blood is too high, it is called hyperlipidaemia. Lipids are made naturally in our bodies and are also absorbed from the food we eat. If the levels of lipids are too high, the excess fat is deposited on to the walls of our blood vessels. This can lead to patches like small fatty lumps developing within the lining of some blood vessels. These patches can reduce the flow of blood, and lead to heart disease, stroke, and blood circulation problems.

High levels of lipids do not make people feel ill, but they can cause the problems mentioned above if left untreated. By lowering the levels of fats, gemfibrozil helps to prevent these long-term heart and circulation problems. Your treatment will be more successful if you also follow the healthy lifestyle advice given by your doctor.

It is likely that you will be prescribed gemfibrozil if you have a high level of a lipid called triglyceride. It may also be given for other types of hyperlipidaemia, especially if other medicines (called statins) are not suitable for you.

Before taking gemfibrozil

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking gemfibrozil it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you have problems with the way your kidneys work, or problems with the way your liver works.

  • If you have bile and gallbladder problems, or gallstones.

  • If you have an underactive thyroid gland.

  • Om du har diabetes.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • If you have ever had an allergic or bad reaction to a medicine.

How to take gemfibrozil

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about gemfibrozil, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take gemfibrozil exactly as your doctor tells you to. There are two strengths of gemfibrozil available - a 300 mg capsule and a 600 mg tablet. It is usual to be prescribed 600 mg twice daily (as tablets). Take your doses ½-1 hour before a meal. This is because gemfibrozil is absorbed better when your stomach is empty. It is best to take gemfibrozil with the same meals each day, as this helps remind you to take your doses regularly. The ideal times to take your doses are before your breakfast and evening meal. If your doctor feels that a lower dose would be more suitable for you, your dose will be 900 mg (as one tablet and one capsule) taken once daily, ½-1 hour before your evening meal.

  • Swallow the tablets/capsules whole with a drink of water. Do not break the tablets or open the capsules, as they have an unpleasant taste.

  • If you forget to take a dose, don't worry, just take your next dose when it is due. Do not take two doses together to make up for the forgotten dose.

Få ut det mesta av din behandling

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You will need to have regular blood tests during your treatment with gemfibrozil to check that your blood and liver stay healthy.

  • Your doctor will give you advice about eating a healthy diet, avoiding drinking too much alcohol, reducing the amount of salt in your diet, stopping smoking, and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.

  • If you buy any medicines, check with a pharmacist that they are safe to take with gemfibrozil. This is because gemfibrozil has the potential to interact with other medicines.

  • Treatment with gemfibrozil is usually long-term unless you experience an adverse effect. Continue to take the tablets/capsules unless you are advised otherwise by your doctor.

Can gemfibrozil cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with gemfibrozil. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common

gemfibrozil side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Indigestion

Stick to simple foods - avoid fatty or spicy meals

Common

gemfibrozil side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Tummy (abdominal) pain, wind, feeling sick (nausea)

Stick to simple foods - avoid fatty or spicy meals

Huvudvärk

Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, kontakta din läkare

Diarré

Drick mycket vatten för att ersätta förlorade vätskor

Förstoppning

Try to eat a well-balanced diet and drink several glasses of water each day

A sense of spinning (vertigo), feeling tired

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Skin rash

If this becomes severe or troublesome, speak with your doctor

Viktigt: if you develop any muscle aches or pains, particularly in your legs, you should tell your doctor about it. This is a rare, but potentially serious, side-effect of treatment.

Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.

How to store gemfibrozil

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Vanliga frågor

What is gemfibrozil for?

Gemfibrozil is a lipid-regulating medicine, also known as a fibrate. It is used to treat hyperlipidaemia, which means high levels of lipids (fats) in your blood. Specifically, it helps lower high levels of triglycerides, and can also be used for other types of hyperlipidaemia if statins are not suitable. By reducing these fat levels, gemfibrozil helps to prevent long-term heart and circulation problems that can arise from excess fat deposits in blood vessels.

What is the usual dosage of gemfibrozil?

The usual dosage prescribed is 600 mg twice daily, taken as tablets. These doses should be taken ½-1 hour before a meal, ideally before breakfast and your evening meal. If a lower dose is more suitable, your doctor might prescribe 900 mg once daily (as one tablet and one capsule) taken ½-1 hour before your evening meal.

Why do I need regular blood tests while taking gemfibrozil?

You need regular blood tests while on gemfibrozil to allow your doctor to monitor your progress and ensure your blood and liver remain healthy. This is an important part of managing your treatment effectively.

Can I take other medicines or supplements with gemfibrozil?

It's important to be cautious when taking other medicines or supplements with gemfibrozil because it has the potential to interact with them. If you buy any over-the-counter medicines, herbal remedies, or complementary medicines, you should check with a pharmacist to ensure they are safe to take alongside gemfibrozil.

How should I store gemfibrozil?

Gemfibrozil should be stored in a cool, dry place, away from direct heat and light. It's also crucial to keep all medicines out of the reach and sight of children to prevent accidental ingestion.

What should I do if I think I've taken too much gemfibrozil?

If you suspect that you or someone else might have taken an overdose of gemfibrozil, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty, as this will help healthcare professionals.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 11 Jul 2027
  • 12 Jan 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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