Orphenadrine
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 7 Aug 2023
Uppfyller patientens redaktionella riktlinjer
- Ladda nerLadda ner
- Dela
- Language
- Diskussion
- Ljudversion
- Lägg till i föredragna källor på Google
Orphenadrine is usually prescribed to relieve unwanted side-effects caused by certain other medicines.
When starting your treatment your doctor may give you a low dose and gradually increase it over a few days. This helps your body adjust to the medicine and reduces the risk of side-effects. Take it exactly as your doctor tells you to.
The most common side-effects are a dry mouth, blurred vision, and feeling sick (nausea).
Överblick
Orphenadrine is a medicine used to treat unwanted movement disorders caused by other medicines.
It can also help relieve muscle stiffness in Parkinson's disease.
Take orphenadrine exactly as your doctor tells you, usually three times a day.
Do not stop taking it suddenly if you have been using it for some time.
Common side-effects include dry mouth, feeling sick, blurred vision, or dizziness.
About orphenadrine
Typ av medicin | An antimuscarinic medicine |
Används för | Unwanted 'extrapyramidal side-effects' caused by some medicines |
Tillgänglig som | Tabletter och flytande medicin för oral användning |
Orphenadrine is an antimuscarinic medicine. It is prescribed for people who have unwanted movement disorders as a side-effect of taking certain other medicines, such as some antipsychotic medicines. These movement disorders are often referred to as 'extrapyramidal side-effects' and include things like uncontrolled face and body movements, tremor, and restlessness.
Orphenadrine can also be given to relieve muscle stiffness in people with Parkinsons sjukdom, although other medicines are generally preferred.
Before taking orphenadrine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking orphenadrine it is important that your doctor knows:
Om du är gravid eller ammar.
If you have any problems with the way your liver works, or the way your kidneys work.
If you have any problems with your heart or blood vessels.
If you have prostate problems, or if you have been experiencing difficulty passing urine.
If you have been constipated for more than a week.
If you have a condition which causes raised pressure in your eyes, such as glaucoma.
Om du har högt blodtryck.
Om du har ett tillstånd som orsakar muskelsvaghet, kallat myasthenia gravis.
If you have ever had a mental health problem called psychosis.
Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take orphenadrine
Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about orphenadrine and will provide you with a full list of the side-effects which you may experience from taking it.
Take orphenadrine exactly as your doctor tells you to. When starting this treatment your doctor may give you a low dose and gradually increase it every 2-3 days until your symptoms improve. Carefully follow the directions your doctor gives to you. Once you are on a full dose, it is likely that you will be taking three doses of orphenadrine a day, although it may be more or less often than this.
You can take orphenadrine before or after your meals. Try to take your doses at the same times of day each day, as this will help you to remember to take your doses regularly.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you buy any medicines, check with a pharmacist that they are safe to take with orphenadrine. Some antihistamines and some strong painkillers can interfere with orphenadrine and increase the risk of side-effects.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking orphenadrine.
If you have been taking orphenadrine for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually if this becomes necessary.
Ask your doctor for advice before drinking alcohol while you are on orphenadrine. Your doctor may recommend that you do not drink alcohol because it increases the possibility of side-effects such as feeling sleepy.
Can orphenadrine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with orphenadrine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common orphenadrine side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Torr mun | Try chewing sugar-free gum or sucking sugar-free sweets. If this becomes troublesome, speak with your doctor |
Feeling sick (nausea) or being sick (vomiting) | Stick to simple foods - avoid rich or spicy meals |
Blurred vision, feeling dizzy or restless | If this happens, do not drive and do not use tools or machines |
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
How to store orphenadrine
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Is orphenadrine a painkiller?
Orphenadrine is not primarily a painkiller. It is an antimuscarinic medicine prescribed to manage unwanted movement disorders that can be side-effects of other medications, particularly some antipsychotic medicines. It can also help with muscle stiffness in people with Parkinson's disease.
How long does it take for orphenadrine to start working for extrapyramidal side-effects?
The article states that when starting treatment, a doctor may begin with a low dose and gradually increase it every 2-3 days until symptoms improve. This suggests that the full therapeutic effect might not be immediate and symptoms improve over this adjustment period.
Can I take orphenadrine if I am taking other medications, even over-the-counter ones?
It is important to inform your doctor about all medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. Some antihistamines and strong painkillers, in particular, can interfere with orphenadrine and increase the risk of side-effects.
What should I do if I forget to take a dose of orphenadrine?
If you forget a dose, take it as soon as you remember, unless your next dose is nearly due. If it's almost time for your next dose, skip the forgotten one and just take the next scheduled dose. Never take two doses together to compensate for a missed dose.
What should I do if the common side-effects of orphenadrine, like dry mouth or blurred vision, don't go away?
The unwanted effects usually improve as your body adjusts to the medicine. However, if side-effects like dry mouth continue or become troublesome, or if you experience blurred vision, feeling dizzy or restless, you should speak with your doctor or pharmacist for further advice.
Does orphenadrine require any special storage conditions?
Yes, orphenadrine should be kept out of the reach and sight of children. It also needs to be stored in a cool, dry place, away from direct heat and light.
Vidare läsning och referenser
- Manufacturer's PIL, Orphenadrine Hydrochloride 50 mg/5 ml Oral Solution; Rosemont Pharmaceuticals Limited, The electronic Medicines Compendium. Dated July 2020.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 6 Aug 2026
7 Aug 2023 | Senaste versionen

Fråga, dela, anslut.
Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.
Anmäl dig till Patientens nyhetsbrev
Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.
Genom att prenumerera accepterar du våra Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.
Mer om läkemedel för nervsystemet
- Agomelatine tablets
- Amisulprid
- Aripiprazol långtidsverkande injektion
- Bromocriptine
- Clomethiazole
- Doxepin kapslar
- Ethosuximid för epilepsi
- Flufenazin långtidsverkande injektion
- Levomepromazin tabletter
- Lithiumtabletter och flytande medicin
- Mianserin för depression
- Morfin för smärtlindring
- Pericyazine
- Fenytoin för epilepsi
- Pizotifen-tabletter
- Rasagilin för Parkinsons sjukdom
- Rimegepant för migränhuvudvärk
- Risperidon långtidsverkande injektion
- Sulpirid
- Tolcapon för Parkinsons sjukdom