Gefitinib-tabletter
Iressa
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 4 Jul 2023
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Gefitinib is given for lung cancer. It is taken once a day.
You will need to have regular check-ups so it is important that you keep your appointments with your doctor and/or hospital.
Contact your doctor straightaway if you suddenly feel short of breath, if you develop a cough or an infection, or if your eyes become irritated.
Överblick
Gefitinib is a chemotherapy medicine for treating some types of lung cancer.
It works by blocking chemical messengers that tell cancer cells to grow.
Ta en tablett dagligen, med eller utan mat, vid samma tidpunkt varje dag.
You can swallow the tablet whole or dissolve it in water.
Tell your doctor if you develop a dry cough, high temperature, or breathing problems.
Common side-effects include diarrhoea, feeling sick, and tiredness.
Do not get pregnant while taking gefitinib and discuss contraception with your doctor.
About gefitinib
Typ av medicin | A tyrosine kinase inhibitor chemotherapy medicine |
Används för | Treatment of lung cancer |
Även kallad | Iressa® |
Tillgänglig som | Tabletter |
Gefitinib is a medicine which is given to treat some types of lung cancer.
In cancer, certain cells in the body grow and multiply in a way that is 'out of control'. Chemotherapy (anti-cancer) medicines work by inhibiting the way cells grow and increase in number. Gefitinib belongs to a group of anti-cancer medicines known as tyrosine kinase inhibitors. These medicines work by blocking chemical messengers (called tyrosine kinases) which send signals to cells to grow. This stops cancer cells from growing and spreading.
Before taking gefitinib
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking gefitinib it is important that your doctor knows:
If you have an infection or feel particularly unwell.
If you have any problems with the way your liver works or if you have ever had hepatitis B infection.
Om du har några problem med hur dina njurar fungerar.
Om du är gravid eller ammar.
Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take gefitinib tablets
Before you start the treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside the pack of tablets. These will give you more information about gefitinib and will provide a full list of the side-effects which you may experience from taking it.
Gefitinib will be prescribed for you by a specialist doctor who is experienced in treating your condition. The usual dose is one tablet daily. It is important that you take the tablets exactly as you are told to by your doctor. The directions for taking the tablets will be printed on the label of the pack to remind you, but if you are still unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
Try to take your tablet at the same time of day each day, as this will help you to remember to take your doses regularly. You can take it before or after meals.
You can swallow the tablet with a drink of water, or if you prefer, you can mix the tablet into a glass of water. To do this, gently stir the tablet into half a glassful of water and allow it to dissolve completely - this may take about 20 minutes. Drink the contents of the glass as soon as the tablet has dissolved, and then add some more water to your glass and drink this too.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, do not take the forgotten dose, as you should not take two doses on the same day.
Få ut det mesta av din behandling
You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular check-ups during treatment. If at any time you develop a dry cough, a high temperature, or a sudden problem with your breathing, you must let your doctor know about it straightaway so that it can be investigated.
If you buy or take any other medicines, check with a pharmacist that they are suitable to take alongside gefitinib. You should not take any preparations which contain St John's wort (a herbal remedy used for low moods), as it can reduce the effectiveness of gefitinib.
If you are having an operation or dental treatment, always tell the person carrying out the treatment which medicines you are taking.
It is important that you do not get pregnant while you are taking gefitinib. If relevant, make sure you discuss with your doctor which types of contraception are suitable for you and your partner.
Can gefitinib cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with gefitinib. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common gefitinib side-effects (these may affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Diarré | Drink plenty of water. If this continues or becomes severe, you should let your doctor know |
Feeling sick (nausea) or being sick (vomiting) | Håll dig till enkla måltider - undvik rik eller kryddstark mat |
Feeling tired or weak | Do not drive and do not use tools or machines unless you feel well enough |
Sore or dry mouth | Ask your doctor or pharmacist to recommend a suitable remedy |
Problems with eyesight, cough, sudden problems with breathing, high temperature, infections | Speak with your doctor as soon as possible |
Loss of weight, lack of appetite, nosebleeds and other bleeding, itchy skin rash, nail problems, hair loss | If any become troublesome, speak with your doctor |
Changes to some blood tests | Your doctor will regularly check for these |
If you experience any other symptoms which you think may be due to the tablets, ask your doctor or pharmacist for advice.
How to store gefitinib
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Please return any unused or unwanted tablets to your clinic or pharmacy to destroy.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Osäker på att blanda mediciner?
Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can gefitinib be used to treat all types of lung cancer?
Gefitinib is specifically given to treat 'some types' of lung cancer, indicating it's not a universal treatment for every lung cancer diagnosis. Its effectiveness depends on specific characteristics of the cancer that it targets.
How does gefitinib specifically target cancer cells without harming healthy cells as much as traditional chemotherapy?
Gefitinib is a tyrosine kinase inhibitor. It works by blocking specific chemical messengers (tyrosine kinases) that signal cancer cells to grow and spread. This targeted action helps to stop the growth of cancer cells.
What should I do if the side-effects of gefitinib don't improve after a while?
While unwanted effects often improve as your body adjusts to the new medicine, you should speak with your doctor or pharmacist if any side-effects continue or become troublesome.
Is it safe to take herbal remedies, like St John's wort, while on gefitinib?
You should not take any preparations which contain St John's wort, as it can reduce the effectiveness of gefitinib. Always check with a pharmacist if you plan to take any other medicines, including herbal remedies, alongside gefitinib.
What should I do if I accidentally take more than the prescribed dose of gefitinib?
If you suspect that you or someone else might have taken an overdose of gefitinib, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.
How should I dispose of any leftover or expired gefitinib tablets?
Do not keep out-of-date or unwanted medicines. You should return any unused or unwanted tablets to your clinic or local pharmacy, and they will dispose of them for you safely.
Vidare läsning och referenser
- Manufacturer's PIL, Iressa® 250 mg film-coated tablets; AstraZeneca UK Limited, The electronic Medicines Compendium. Dated October 2022.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
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Nästa granskning: 3 jan 2028
4 Jul 2023 | Senaste versionen

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