Glyceryltrinitrat rektalsalva

Rectogesic

Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 20 okt 2024

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Glyceryl trinitrate rectal ointment can ease the pain associated with small tears of skin around the back passage (anal fissures).

Use the ointment twice daily at 12-hourly intervals. You can use it for up to eight weeks if necessary.

The most common side-effect is a headache.

About glyceryl trinitrate rectal ointment

Typ av medicin	A nitrate
Används för	Pain relief for anal fissures (in adults)
Även kallad	Nitroglycerin (in US); Rectogesic®
Tillgänglig som	Rectal ointment

En anal fissur is a small tear of the skin around your back passage (anus). Glyceryl trinitrate (GTN) rectal ointment (Rectogesic®) works by relaxing the muscle just inside your back passage. Relaxing this muscle increases the flow of blood to the area, which eases pain. It can be helpful where other treatments have not been effective.

A different brand of glyceryl trinitrate ointment (Percutol®) is used to relieve angina pain. For information on this product please see our medicine leaflet Glyceryltrinitrat för kärlkramp.

Before using glyceryl trinitrate rectal ointment

To make sure that this is the right treatment for you, before you start using GTN rectal ointment it is important that your doctor knows:

Om du är gravid eller ammar.
Om du har några problem med hur din lever fungerar, eller några problem med hur dina njurar fungerar.
If you have migraines or severe headaches.
If you have low blood pressure, or a heart condition.
If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia).
Om du har en underaktiv sköldkörtel.
If you have an eye condition called glaucoma.
If you have recently had a head injury or a heart attack.
Om du någonsin har haft en allergisk reaktion mot en medicin.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction.

How to use glyceryl trinitrate rectal ointment

Before you use the ointment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about using the ointment, and it will also provide you with a full list of side-effects which you could experience.
Cover your finger with a finger cot (available from pharmacies), or a piece of cling film, or use a disposable glove. Then measure out 2.5 cm of the ointment from the tube on to your finger (there is a measuring line on the packaging to help you). Then, using your finger, gently insert the ointment just inside your back passage. To make sure that the ointment gets to the correct place, insert your finger to the first finger joint. Apply the ointment this way every 12 hours until the pain goes away. You can continue to use the ointment for up to eight weeks, if needed.

Få ut det mesta av din behandling

Remember to follow any lifestyle or dietary advice you have been given by your doctor. Try to avoid becoming constipated, by eating a high-fibre diet and drinking several glasses of water each day.
It is best not to drink alcohol while you are using GTN rectal ointment. Alcohol will increase the chance that you experience side-effects such as feeling dizzy and light-headed.
If you experience any bleeding from your back passage, or if your symptoms do not improve, you should discuss this with your doctor.
If you buy any medicines, check with a pharmacist that they are suitable for you to take while you are using GTN rectal ointment.

Can glyceryl trinitrate rectal ointment cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with GTN rectal ointment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common glyceryl trinitrate rectal ointment side-effects (these affect more than 1 in 10 people)	Vad kan jag göra om jag upplever detta?
Huvudvärk	Ask your pharmacist to recommend a suitable painkiller. If the headache is severe or if it continues, please ask your doctor for further advice
Common glyceryl trinitrate rectal ointment side-effects (these affect fewer than 1 in 10 people)	Vad kan jag göra om jag upplever detta?
Feeling light-headed or dizzy	Kör inte och använd inte verktyg eller maskiner när du är påverkad
Känner dig illamående (nausea)	Try to stick to simple meals (avoid rich or spicy foods). If it becomes troublesome, please speak with your doctor
Less common glyceryl trinitrate rectal ointment side-effects	Vad kan jag göra om jag upplever detta?
Blurred vision, diarrhoea, local burning or itching	If any become troublesome, please speak with your doctor

If you experience any other symptoms which you think may be due to the ointment, please speak with your doctor or pharmacist for further advice.

How to store glyceryl trinitrate rectal ointment

Once opened, do not store or use the ointment for longer than eight weeks.
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking/using.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Vanliga frågor

How should I store glyceryl trinitrate rectal ointment?

You should store the ointment in a cool, dry place, away from direct heat and light. It's important to keep all medicines out of the reach and sight of children. Once you've opened the tube, do not store or use the ointment for longer than eight weeks.

What should I do if my symptoms don't improve or if I experience bleeding?

If you notice any bleeding from your back passage, or if your symptoms do not get better despite using the ointment as directed, you should discuss this with your doctor.

What should I do if I accidentally use too much ointment?

Never use more than the prescribed dose. If you suspect that someone might have swallowed some of the ointment by accident, you should go to the accident and emergency department of your local hospital immediately. Remember to take the ointment container with you, even if it's empty.

Are there any specific situations where I need to mention I'm using this ointment to other healthcare professionals?

Yes, if you are having an operation or dental treatment, it's very important to tell the person carrying out the treatment which medicines you are taking or using, including glyceryl trinitrate rectal ointment.

Can I use other medicines, including over-the-counter ones, with glyceryl trinitrate rectal ointment?

If you are considering buying any other medicines, including those available without a prescription, you should check with a pharmacist to ensure they are suitable for you to take while you are using GTN rectal ointment. It's particularly important to inform your doctor about any medicines you are using to treat erectile dysfunction, as well as any herbal or complementary medicines.

Dessa frågor och svar har genererats från informationen i denna artikel.

Vidare läsning och referenser

Manufacturer's PIL, Rectogesic® 4 mg/g Rectal Ointment; Grunenthal Meds, Kyowa Kirin International UK NewCo Ltd, The electronic Medicines Compendium. Dated February 2024.
Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.