Dexketoprofen for pain
Keral
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 19 Jan 2023
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Dexketoprofen is a painkiller. It is called a non-steroidal anti-inflammatory drug. It is also known as an 'NSAID'.
The usual dose is either half a 25 mg tablet every 4-6 hours, or one 25 mg tablet every eight hours. Your doctor will tell you which dose is right for you.
Pain relief is more rapid if dexketoprofen is taken when your stomach is empty - this means taking the tablets about 30 minutes before food.
The most common side effects of dexketoprofen are feeling sick (nausea), indigestion, and stomach pain.
At a glance
Dexketoprofen is an anti-inflammatory painkiller for short-term painful conditions.
It can treat muscular sprains, period pain, and toothache.
Common side effects include indigestion, heartburn, stomach pain, feeling or being sick, and diarrhoea.
Take tablets with water; they work faster on an empty stomach.
Avoid alcohol while taking this medicine.
If you have asthma and experience wheezing or breathlessness, stop taking the tablets and see your doctor.
If you pass blood or black stools, or have severe stomach pains, seek immediate medical advice.
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About dexketoprofen
Typ av medicin | Ett icke-steroid antiinflammatoriskt läkemedel (NSAID) |
Används för | Short-term painful conditions |
Även kallad | Keral®; Skudexa® (dexketoprofen with tramadol) |
Tillgänglig som | Tabletter |
What is dexketoprofen used for?
Tillbaka till innehållDexketoprofen is a type of anti-inflammatory painkiller called non-steroidal anti-inflammatory drugs (NSAIDs).
It is used to treat short-term painful conditions such as muscular sprains and strains, period (menstrual) pain, and toothache.
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How does dexketoprofen work?
Tillbaka till innehållDexketoprofen works by blocking COX enzymes in the body. These enzymes help produce prostaglandins, chemicals that cause pain and inflammation.
When dexketoprofen blocks COX enzymes, fewer prostaglandins are made, so pain and inflammation decrease.
Side effects of dexketoprofen
Tillbaka till innehållCommon side effects of dexketoprofen include:
Indigestion.
Heartburn.
Magont.
Illamående.
Kräkningar.
Diarré.
A full list of the side effects can be found in the manufacturer's printed information leaflet supplied with the medicine. Speak with your doctor or pharmacist if any side effects continue or become troublesome.
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How to manage dexketoprofen side effects
Tillbaka till innehållCommon dexketoprofen side effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Indigestion, heartburn, stomach pain | Om det är besvärligt, prata med din läkare |
Feeling sick or being sick, diarrhoea | Drink plenty of liquid to replace any lost fluids. Try taking the tablets after meals |
Viktigt: if you experience any of the following rare but possibly serious symptoms, stop taking dexketoprofen and contact your doctor for advice straightaway:
Om du har några andningssvårigheter som väsande andning eller andfåddhet.
If you have any signs of an allergic reaction such as swelling around your mouth or face, or an itchy skin rash.
If you pass blood or black stools, bring up (vomit) blood, or have severe stomach pains.
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
Who should not take dexketoprofen?
Tillbaka till innehållSome medicines aren’t suitable for everyone. Before taking dexketoprofen, your doctor needs to know:
If you have ever had a stomach or duodenal ulcer, or if you have an inflammatory bowel disorder such as Crohns sjukdom or ulcerös kolit.
Om du har astma eller någon annan allergisk sjukdom.
Om du är gravid, försöker bli gravid eller ammar.
Om du har några problem med hur din lever fungerar, eller om du har några problem med hur dina njurar fungerar.
If you have a heart condition or a problem with your blood vessels or circulation.
If you have högt blodtryck.
If you have any blood clotting problems.
Om du har högt blodsocker eller kolesterolnivåer.
Om du har en bindvävssjukdom som systemisk lupus erythematosus. Detta är ett inflammatoriskt tillstånd som också kallas lupus eller SLE.
If you are taking any other medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to any other NSAID (such as aspirin, ibuprofen, diclofenac, and indometacin), or to any other medicine.
How to take dexketoprofen
Tillbaka till innehållRead the leaflet that comes with the medicine before you start. It explains how dexketoprofen works and lists possible side effects.
Depending on your condition, you may take half a tablet every 4-6 hours or one tablet every 8 hours. Stop taking the tablets once the pain has gone.
Do not take more than three 25 mg tablets per day.
Take the tablets with water. They work faster on an empty stomach (about 30 minutes before food), but if they make you feel sick, take them after eating.
If you forget a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at once.
Få ut det mesta av din behandling
Tillbaka till innehållYour doctor will prescribe the lowest dose for the shortest time to reduce side effects.
Keep any follow-up appointments with your doctor. This is so your doctor can check on your progress.
If you have asthma, symptoms such as wheeze or breathlessness can be made worse by dexketoprofen. If this happens to you, you should stop taking the tablets and see your doctor as soon as possible.
Check with a pharmacist before taking any other medicines. Do not take dexketoprofen with other anti-inflammatory painkillers, including some over-the-counter cold and flu remedies.
Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
How to store dexketoprofen
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållHow long does it take for dexketoprofen to work?
Dexketoprofen usually starts to work within 30 minutes after taking it, with full pain relief often felt after about 1 hour.
Can you drink alcohol with dexketoprofen?
It’s best to avoid alcohol while taking dexketoprofen. Drinking alcohol can increase the risk of stomach irritation, indigestion, or bleeding, especially if the medicine is taken regularly or on an empty stomach.
Is it safe to take dexketoprofen during pregnancy?
Dexketoprofen is not recommended during pregnancy, particularly in the third trimester, as it may cause complications for the baby. Let your doctor know if you are pregnant or are planning on becoming pregnant.
Is dexketoprofen stronger than ibuprofen?
Dexketoprofen is a more active form of ibuprofen, so smaller doses may work faster and may be more effective for some types of pain.

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Vidare läsning och referenser
- Manufacturer’s PIL, Keral® 25 mg tablets; A. Menarini Farmaceutica Internazionale SRL, The electronic Medicines Compendium. Dated June 2022.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 18 Jul 2027
19 Jan 2023 | Senaste versionen

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