Doxepin kapslar
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 7 Aug 2023
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Keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Common side effects of doxepin include sleepiness, dry mouth, constipation, blurred vision, and dizziness.
Doxepin may make you feel sleepy. If this happens, do not drive and do not use tools or machines. Do not drink alcohol.
Tell your doctor if you experience any troublesome side effects.
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About doxepin
Typ av medicin | A tricyclic antidepressant |
Används för | The treatment of depression in adults aged 18 and over |
Tillgänglig som | Kapslar |
What is doxepin used for?
Doxepin is used for the treatment of depression. It belongs to a group of medicines called tricykliska antidepressiva.
Doxepin can help ease the symptoms of depression and is particularly helpful if you also have difficulty sleeping. It is thought to work by interfering with brain chemicals (called neurotransmitters) which may be involved in causing symptoms of depression.
The exact cause of depression is not known. It can develop for no apparent reason or it may be triggered by a life event such as a relationship problem, bereavement, or illness. With depression you have a consistently low mood and other symptoms severe enough to interfere with your normal day-to-day activities.
Side effects of doxepin
The most common side effects of doxepin are:
Känner mig sömnig eller trött.
Torr mun.
Förstoppning.
Blurred vision.
Dizziness - especially when getting up from a sitting or lying position.
Huvudvärk.
Känna sig illamående (illamående).
Kräkningar.
Svettas.
Du hittar en fullständig lista i tillverkarens informationsblad som medföljer din medicin. De oönskade effekterna förbättras ofta när din kropp anpassar sig till den nya medicinen, men tala med din läkare eller apotekare om något av följande fortsätter eller blir besvärligt.
How to manage doxepin side effects
Common doxepin side effects | Vad kan jag göra om jag upplever detta? |
Blurred vision, feeling sleepy or tired | Om detta händer, kör inte och använd inte verktyg eller maskiner. Drick inte alkohol |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Förstoppning | Try to eat a well-balanced diet containing plenty of fibre and drink plenty of water |
Feeling faint or light-headed, especially when getting up from a sitting or lying position | Getting up more slowly may help. If you begin to feel faint, sit down until the feeling passes |
Huvudvärk | Be din apotekare att rekommendera en lämplig smärtstillande |
Feeling sick or being sick, diarrhoea | Stick to simple meals - avoid rich or spicy foods. Drink plenty of water to replace lost fluids |
Sweating, flushing, difficulty in passing urine, increased appetite, feeling confused or anxious, disturbed sleep, lack of concentration, feeling shaky, itchy skin rash, weight changes, changes in sexual function, breast tenderness, changes in the way things taste, ringing in your ears, fast heartbeat | Om något av dessa blir besvärligt, tala med din läkare för råd |
Viktigt: I sällsynta fall kan läkemedel som påverkar serotoninnivån i hjärnan göra att den blir för hög och orsaka problem. Risken är större om du tar mer än ett läkemedel med denna effekt. Sök vård om du får en kombination av följande symtom:
Stela muskler eller ryckiga rörelser.
Ovanligt snabb hjärtrytm.
Hög temperatur (feber), illamående eller kräkningar, diarré.
Känner dig förvirrad eller ser syner (hallucinerar).
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
Who should not take doxepin?
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking doxepin it is important that your doctor knows:
Om du är gravid eller ammar.
If you have an overactive thyroid gland.
Om du har några problem med hur din lever fungerar, eller hur dina njurar fungerar.
If you have epilepsy or diabetes (diabetes mellitus).
If you have had problems with constipation over a long time.
If you have any difficulties passing urine, or if you have had prostate trouble.
If you have a heart disorder or blood vessel disease.
If you have had a mental health problem - in particular, bipolar disorder or psychosis.
If you have increased pressure in your eyes (glaucoma).
If you have been told you have phaeochromocytoma - a tumour on your adrenal gland.
If you have porphyria - a rare inherited blood disorder.
If you are taking other medicines, including those available to buy without a prescription, as well as herbal and complementary medicines. This is especially important if you have recently taken a medicine for depression, known as a monoamine-oxidase inhibitor (MAOI).
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take doxepin capsules
Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about doxepin and will provide you with a full list of the side effects which you may experience from taking it.
Doxepin can make you feel sleepy so your doctor may advise you to take a small dose when you first start taking it, and then to increase your dose gradually as your body gets used to it.
Doxepin is often prescribed once a day at bedtime, although it can also be taken two or three times a day. Your doctor will tell you which is right for you and the directions will be printed on the label of the pack to remind you what the doctor has said.
If you have any questions about how to take the capsules, ask your pharmacist for advice.
You can take doxepin before or after meals. Many people find if helps to swallow the capsule with a drink of water.
If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, then take the next dose when it is due but leave out the forgotten dose. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
You may feel that doxepin is not working for you straightaway. It can take a week or two for the effect to build up, and 4-6 weeks before you feel the full benefit. It is important that you do not stop taking it thinking that it is not helping.
While you feel depressed, you may have distressing thoughts and think about harming yourself or ending your life. If this happens, it is very important that you tell your doctor about it straightaway.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on doxepin as it increases the risk of side effects, such as feeling sleepy.
There are several types of antidepressants - each type works in a slightly different way and can have different side effects. If you find that doxepin does not suit you then let your doctor know, as another antidepressant may be found that does.
Some people who take doxepin find that their skin becomes more sensitive to sunlight than usual. Do not use sunbeds and try to avoid strong sunlight until you know how your skin reacts. Use a sun cream with a high sun protection factor.
Your doctor may ask you to carry on taking doxepin even after you feel better. This is to help stop your symptoms from returning.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. This is because a number of medicines can increase the risk of side effects from doxepin, including some painkillers, flu remedies and antihistamines.
If you have diabetes you may need to check your blood sugar (glucose) more frequently. This is because doxepin can alter the levels of sugar in your blood. Your doctor will advise you about this.
If you are due to have any medical treatment, tell the person carrying out the treatment that you are taking a tricyclic antidepressant, as they can interfere with some anaesthetics.
Continue to take doxepin unless your doctor tells you otherwise. Stopping treatment suddenly can sometimes cause problems and your doctor may want you to reduce your dose gradually if this becomes necessary.
How to store doxepin capsules
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.
Vanliga frågor
Can you get doxepin in the UK?
Yes, doxepin is available in the UK, but it’s not commonly prescribed compared to newer antidepressants. It may be used for depression, anxiety, or sometimes for sleep problems, but usually only when other options haven’t worked.
Is doxepin better than Xanax?
Doxepin and Xanax (alprazolam) work in very different ways. Doxepin is a tricyclic antidepressant and Xanax is a benzodiazepine, mainly prescribed short-term for anxiety or panic, as it can cause dependence if used for too long. Which is “better” depends on your condition and medical history.
How effective is doxepin for sleep?
Doxepin at low doses is sometimes prescribed to help with insomnia as it might improve sleep quality by reducing how often you wake up during the night and helping you stay asleep longer. It’s generally considered effective, especially for people who have trouble staying asleep, but it may not work for everyone.
Vidare läsning och referenser
- Manufacturer's PIL, Doxepin 25 mg and 50 mg Capsules; Marlborough Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated May 2021.
Om recensentenVisa fullständig biografi

Dr Colin Tidy, MRCGP
Allmänläkare, Medicinsk Författare
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy är en NHS-läkare, baserad i Oxfordshire.
Artikelhistorik
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 6 Feb 2028
7 Aug 2023 | Senaste versionen
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