Paroxetine
Seroxat
Granskad av Dr Colin Tidy, MRCGPSenast uppdaterad av Michael Stewart, MRPharmSLast updated 30 Aug 2023
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Take paroxetine in the morning with your breakfast or a snack.
It may take a few weeks after starting the treatment for paroxetine to work. Do not stop taking it, even if you feel like it is not helping.
Common side effects of paroxetine include feeling sick (nausea), headache, diarrhoea, feeling sleepy, dizzy or weak, and trouble sleeping.
Tell your doctor if you feel that you are not getting any better, or if you experience any troublesome side effects.
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About paroxetine
Typ av medicin | A selective serotonin reuptake inhibitor (SSRI) antidepressant |
Används för | Adults with depression, anxiety disorders, or obsessive-compulsive disorder (OCD) |
Även kallad | Seroxat® |
Tillgänglig som | Tabletter och flytande medicin för oral användning |
What is paroxetine used for?
Tillbaka till innehållParoxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It is used to treat depression, anxiety disorders, and obsessive-compulsive disorder.
Selective serotonin reuptake inhibitors (SSRIs) like paroxetine increase the amount of circulating serotonin available in your brain. Altering the balance of the chemicals in the brain can help improve symptoms of depression, anxiety disorders, and OCD.
Depression can develop for no apparent reason, or it can be triggered by a life event such as a relationship problem, a bereavement, or an illness. An anxiety disorder is a condition where anxiety is a major symptom. Panic disorder, social anxiety disorder, and post-traumatic stress disorder are all anxiety disorders. Obsessive-compulsive disorder is a condition where you have recurring and persistent ideas that make you do repetitive actions.
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Side effects of paroxetine
Tillbaka till innehållThe most common side effects of paroxetine are:
Illamående.
Kräkningar.
Diarré.
Förstoppning.
Blurred vision.
Feeling dizzy, sleepy or weak.
Torr mun.
Headache.
Feeling anxious, nervous or agitated.
Feeling restless and shaky.
Svettas.
Yawning.
Trouble sleeping.
Reduced sex drive (libido).
You will find a full list in the manufacturer's information leaflet supplied with your medicine.
The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
How to manage paroxetine side effects
Tillbaka till innehållCommon paroxetine side effects | Vad kan jag göra om jag upplever detta? |
Feeling sick or being sick, diarrhoea or constipation | Stick to simple foods and drink plenty of water |
Blurred vision, lack of concentration, feeling dizzy, sleepy or weak | If this happens, do not drive and do not use tools or machines until you feel better |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Mood changes such as feeling anxious, nervous, or agitated. Feeling restless or shaky | These usually settle within a few days. If any become troublesome or severe, speak with your doctor |
Sweating, yawning, difficulty sleeping, abnormal dreams, increased weight, reduced sexual drive or ability | Om något av dessa blir besvärligt, tala med din läkare |
Viktigt: a few people taking paroxetine have developed an allergic-type reaction. You should contact your doctor straightaway if you develop any swelling around your face, any difficulties breathing, or a severe rash.
On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking more than one medicine with this effect. Seek medical attention if you develop any combination of the following:
Stiff muscles or 'jerky' movements.
Unusually fast heartbeat.
High temperature (fever), feeling sick (nausea) or being sick (vomiting), diarrhoea.
Feeling delirious or seeing visions (hallucinating).
If you experience any other symptoms that you think may be due to this medicine, speak with your doctor or pharmacist for further advice.
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Who should not take paroxetine?
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking paroxetine it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your liver works, or with the way your kidneys work.
Om du har en hjärtsjukdom.
If you have epilepsy.
If you have high blood sugar levels (diabetes mellitus).
If you have an eye problem called glaucoma.
If you have ever had a bleeding disorder.
If you have ever had abnormally 'high' moods, called mania.
If you are being treated with electroconvulsive therapy (ECT).
Om du någonsin har haft en allergisk reaktion mot en medicin.
If you have taken an antidepressant known as a monoamine-oxidase inhibitor (MAOI) within the previous two weeks.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take paroxetine
Tillbaka till innehållRead the manufacturer's printed information leaflet from inside the pack. It will give you more information about paroxetine and will provide you with a full list of the side effects which you may experience from taking it.
Take paroxetine exactly as your doctor tells you to. It is prescribed as a once-daily dose, to be taken in the morning.
There are several strengths of paroxetine tablets - 10 mg, 20 mg, and 30 mg. Your doctor will tell you which strength is right for you.
If you are being treated for a panic disorder, your doctor may prescribe a low dose for you to begin with, and then increase it. This is because some people feel anxious during the first two weeks, and slowly increasing the dose helps to reduce this.
Take paroxetine with a snack or just after eating breakfast, as this will help to reduce the likelihood of you feeling sick as a side effect. Swallow the tablets with a drink of water.
If you are taking liquid medicine, it is recommended that you do not take indigestion remedies during the two hours before or during the two hours after you take paroxetine liquid. This is because antacids can reduce the amount of paroxetine your body absorbs.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållYou may feel that paroxetine is not working for you straightaway. It can take a week or two after starting the treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it even if you feel like it is not helping.
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
While you are taking paroxetine, you may have thoughts about harming yourself or ending your life. These thoughts may also be associated with your condition. It is very important that you tell your doctor about this if it happens.
Do not stop taking paroxetine unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
You should expect that a course of treatment will last for several months. This is normal and helps to prevent your symptoms from recurring.
If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on paroxetine.
If you have diabetes, you may need to check your blood glucose more frequently, as paroxetine may affect the levels of sugar in your blood. Your doctor will advise you about this.
If you buy any medicines, check with a pharmacist that they are safe to take with paroxetine. This is because several medicines which are available from general retail outlets can interfere with the treatment.
In particular, do not take the herbal remedy St John's wort, and ask for advice before buying any anti-inflammatory painkillers.
A few people taking paroxetine find that their skin is more sensitive to sunlight than normal. Until you know how your skin reacts, use a sun cream with a high sun protection factor (SPF) in strong sunlight.
There are several types of antidepressants and they differ in their possible side effects. If you find that paroxetine does not suit you then let your doctor know, as another may be found that will.
How to store paroxetine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Once a bottle of Seroxat® Oral Suspension has been opened it will keep for one month - after this time, make sure you have a fresh supply.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.
Vanliga frågor
Tillbaka till innehållIs paroxetine a strong antidepressant?
Paroxetine is an antidepressant that is effective in improving the symptoms of depression and anxiety. How 'strong' it feels depends on the person.
Can paroxetine cause night sweats?
Paroxetine can sometimes cause side effects such as night sweats when you first start treatment or if your dose changes. Speak to your doctor if night sweats become bothersome or affect your sleep.
Does paroxetine cause weight gain?
Paroxetine may cause weight gain in some people. If you notice changes in weight, speak with your doctor for advice on managing or adjusting treatment.

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Vidare läsning och referenser
- Manufacturer's PIL, Seroxat® 10 mg, 20 mg and 30 mg Tablets; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated September 2022.
- Manufacturer's PIL, Seroxat® 20 mg/10 ml oral suspension; GlaxoSmithKline UK, The electronic Medicines Compendium. Dated September 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 29 Aug 2026
30 Aug 2023 | Senaste versionen

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