Pantoprazole to reduce stomach acid
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 4 Jul 2023
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Pantoprazole reduces the amount of acid produced in your stomach.
Swallow the tablet whole - do not chew or crush it before you swallow.
The most common side-effects are stomach upset and headache. These effects are generally mild and do not last long.
At a glance
Pantoprazole is a medicine that reduces the amount of acid your stomach produces.
It is used to treat stomach ulcers, acid reflux, and H. pylori infection.
You can get pantoprazole on prescription, or buy short courses for reflux at a pharmacy.
You should take pantoprazole tablets with water; do not chew or crush them.
Common side-effects include stomach upset, diarrhoea, constipation, and headache.
Do not drive or use machines if you feel dizzy or tired after taking this medicine.
If purchased for reflux, see a doctor if symptoms do not improve within a few days.
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About pantoprazole
Typ av medicin | Proton pump inhibitor |
Används för | Healing or prevention of gastric or duodenal ulcers; gastro-oesophageal reflux disease; Helicobacter pylori infection; Zollinger-Ellison syndrome |
Tillgänglig som | Tablets and injection |
Acid is produced naturally in your stomach to help you digest food and to kill bacteria. This acid is irritant so your body produces a natural mucous barrier which protects the lining of your stomach. In some people, this barrier can break down allowing the acid to damage the stomach, causing inflammation, sår and other conditions. Other people can have a problem with the muscular band at the top of the stomach that keeps the stomach tightly closed. This may allow the acid to escape and irritate the oesophagus, causing heartburn. This is often referred to as 'halsbränna'.
Proton pump inhibitors such as pantoprazole stop cells in the lining of the stomach from producing too much acid. This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn. Pantoprazole is also given as one part of a treatment to get rid of Helicobacter pylori, a bacterium found in the stomach, which can cause ulcers.
Pantoprazole is available on prescription. You can also buy short courses of pantoprazole at a pharmacy for the treatment of reflux symptoms (such as heartburn) in adults.
Before taking pantoprazole
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking pantoprazole it is important that your doctor or pharmacist knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any of the following symptoms: difficulty swallowing, loss of blood, weight loss, or if you are being sick (vomiting).
If you have any problems with the way your liver works, or with the way your kidneys work.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
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How to take pantoprazole
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pantoprazole and will provide you with a full list of the side-effects which you may experience from taking it.
If you have been prescribed pantoprazole, take it exactly as your doctor tells you to. There are different strengths of tablets available so your doctor will tell you which is right for you. It is usually taken once a day. If you are taking it for either Helicobacter pylori eradication or for Zollinger-Ellison syndrome, it is likely you will be asked to take two doses a day. Your doctor will tell you which dose is right for you and the directions will also be on the label of the pack to remind you.
If you have bought pantoprazole for symptoms such as heartburn, take one tablet in the morning. You may need to take pantoprazole for a day or so to control your symptoms. If your symptoms do not improve within a few days, you should talk with your doctor about this.
Swallow the tablets with a drink of water. Do not chew, crush or break the tablet before you swallow. Pantoprazole can be taken before or after food, although taking it before food is preferable.
If you forget to take a dose at your usual time, you can take it when you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
Tillbaka till innehållTry to keep your regular appointments with your doctor. This is so your progress can be checked. If you are taking pantoprazole on a long-term basis your doctor will want to review your treatment at least once a year to make sure it is still right for you.
A typical course of treatment lasts for one or two weeks if you are taking pantoprazole for Helicobacter pylori eradication. It will last for one or two months if it is to allow an ulcer to heal. For all other reasons for taking pantoprazole, your treatment will last for as long as is necessary to control your symptoms.
Some foods may make your symptoms worse. Foods and drinks that have been suspected of this include peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks. If it seems that a food is aggravating your symptoms, try avoiding it for a while to see if your symptoms improve. Also, try avoiding eating large meals, as these can make your symptoms worse too.
If you are overweight, it puts extra pressure on your stomach and encourages the symptoms of acid reflux. Losing some weight and eating a healthy balanced diet may help you.
Smoking increases the amount of acid produced by the stomach and may make your symptoms worse. If you are a smoker, speak with your doctor or pharmacist about how to quit.
Recent studies suggest that there may be a slight increase in the risk of bone fractures when proton pump inhibitors like pantoprazole are taken for longer than a year. If this affects you, your doctor will check that you are taking enough vitamin D and calcium to reduce this risk.
If you buy any medicines 'over the counter', always check with a pharmacist that they are safe to take alongside your other medicines.
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Can pantoprazole cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with pantoprazole. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Pantoprazole side-effects (these affect fewer than 1 in 100 people) | Vad kan jag göra om jag upplever detta? |
Stomach upset (such as feeling sick (nausea), stomach ache, or wind), tummy (abdominal) pain, being sick (vomiting) | Stick to simple meals - avoid rich or spicy foods. If symptoms are severe or do not go away, let your doctor know |
Diarré | Drink plenty of water. If it continues or becomes severe, let your doctor know |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day |
Huvudvärk | Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare |
Feeling dizzy or tired | Kör inte och använd inte verktyg eller maskiner förrän du mår bättre |
Dry mouth, itchy skin rash, sleeping problems | If any of these become troublesome, let your doctor know |
Viktigt: long-term use of pantoprazole (for at least three months) may lead to low levels of magnesium in your blood. Initial signs this might be happening include feeling tired, dizzy or confused and an irregular heartbeat (palpitations). Let your doctor know if you think this applies to you.
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
How to store pantoprazole
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Om du ska genomgå en operation eller någon tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
Can I take pantoprazole if I'm pregnant or breastfeeding?
It's important to let your doctor or pharmacist know if you are pregnant, trying for a baby, or breastfeeding before you start taking pantoprazole. They will advise you on the suitability of the medicine for your situation.
How long will I need to take pantoprazole for?
The duration of your treatment with pantoprazole depends on the reason you are taking it. For Helicobacter pylori eradication, a typical course lasts one to two weeks. If it's to heal an ulcer, it will likely be one to two months. For other conditions, you will take it for as long as needed to control your symptoms.
What should I do if I forget a dose of pantoprazole?
If you forget to take a dose at your usual time, you can take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one. Do not take two doses at once to compensate for a forgotten dose.
Are there any foods or drinks I should avoid while taking pantoprazole?
Certain foods and drinks, such as peppermint, tomatoes, chocolate, spicy foods, hot drinks, coffee, and alcoholic drinks, may worsen symptoms for some people. If you notice a food making your symptoms worse, try avoiding it for a while to see if there's an improvement. Also, consider avoiding large meals, as these can aggravate symptoms.
Can pantoprazole affect the results of an operation or dental treatment?
Yes, if you are having an operation or any dental treatment, you should always inform the person carrying out the treatment about all the medicines you are currently taking, including pantoprazole.
Is it safe to take pantoprazole with other 'over-the-counter' medicines?
If you are buying any medicines without a prescription, always check with a pharmacist to ensure they are safe to take alongside your pantoprazole and any other medicines you are using.
What are the signs of low magnesium from long-term pantoprazole use?
Long-term use of pantoprazole (for at least three months) can potentially lead to low magnesium levels in your blood. Initial signs of this might include feeling tired, dizzy, or confused, and experiencing an irregular heartbeat (palpitations). If you notice these symptoms, you should inform your doctor.
Vidare läsning och referenser
- Manufacturer's PIL, Pantoprazole 20 mg gastro-resistant Tablets; Takeda UK Ltd, The electronic Medicines Compendium. Dated April 2022.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Next review due: 3 Jul 2026
4 Jul 2023 | Senaste versionen

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