Hoppa till huvudinnehåll

Prucalopride for constipation

Resolor

Take one tablet daily.

The most common side-effects are headache, feeling sick (nausea) and diarrhoea.

At a glance

  • Prucalopride is a medicine used to treat long-term constipation in adults.

  • It is typically prescribed when other treatments like lifestyle changes and laxatives have not worked.

  • Prucalopride works by increasing the movement of your bowels, making stools easier to pass.

  • You usually take one tablet once a day, with or without food.

  • Common side-effects include headache, feeling sick, tummy pain, and diarrhoea.

  • Contact your doctor if you are pregnant, have other bowel conditions, or have heart, liver, or kidney problems.

Fortsätt läsa nedan

About prucalopride

Typ av medicin

Selective serotonin 5HT4-receptor agonist

Används för

Förstoppning

Även kallad

Resolor®

Tillgänglig som

Tabletter

Constipation in adults is a common problem. It means either going to the toilet less often than usual to empty the bowels, or passing hard or painful stools when you do go. It can be caused by not eating enough fibre or not drinking enough fluids, or a lack of exercise or movement (such as being ill in bed). It can also be a side-effect of certain medicines (such as some painkillers), or related to an underlying medical condition. In many cases, the cause is not clear.

Prucalopride works on the muscle wall of the bowels. It increases the movement of the bowels, making stools easier to pass. It can be helpful for people for whom constipation remains a problem despite having made changes to lifestyle and diet, and despite having tried a number of different laxatives.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking prucalopride it is important that your doctor knows:

  • Om du är gravid, försöker bli gravid eller ammar.

  • If you are so constipated that you think you may have a blockage.

  • If you have any other bowel condition (such as Crohn's disease, ulcerative colitis or toxic megacolon).

  • If you have a heart condition or have been told that you have an unusual heart rhythm.

  • If you have any problems with the way your liver works or with the way your kidneys work.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

Fortsätt läsa nedan

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about prucalopride and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take prucalopride tablets exactly as your doctor tells you to. It is usual to be prescribed one (2 mg) tablet to take once daily. You may be given a lower-strength tablet if you are over 65 years old, or if you have any problems with your liver or kidneys.

  • Swallow the tablet with a drink of water. You can take the tablet at a time of day to suit you. It is recommended that you take your doses at the same time of day each day, as doing this can help you to remember to take your doses regularly. You can take prucalopride tablets before or after food.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose and take the dose that is due. Do not take two tablets at the same time to make up for a missed dose.

  • Remember to keep any regular appointments with your doctor. This is so your doctor can check on your progress.

  • En hälsosam kost som innehåller fiber (fullkornsbröd och spannmål, kli, frukt och gröna bladgrönsaker) tillsammans med flera glas vatten varje dag och daglig motion är viktigt för att upprätthålla en hälsosam tarmfunktion.

  • You can read our leaflet called Fibre and Fibre Supplements for advice on ways to increase the amount of fibre in your diet.

  • You should avoid getting pregnant while you are taking prucalopride. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.

Fortsätt läsa nedan

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with prucalopride. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common prucalopride side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Huvudvärk

Drick mycket vatten och be din apotekare rekommendera en lämplig smärtstillande. Om huvudvärken fortsätter, informera din läkare

Feeling sick (nausea), tummy (abdominal) pain

This usually passes within a few days. In the meantime eat simple meals - avoid rich or spicy foods

Diarré

Drink plenty of water

Common prucalopride side-effects

(these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling dizzy or tired

Do not drive and do not use tools or machines while you feel dizzy

Indigestion, upset stomach, passing urine frequently, rectal bleeding

Om det är besvärligt, prata med din läkare

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your other medicines.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

symptom checker

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

How quickly should I expect prucalopride to work once I start taking it?

The article states that prucalopride increases the movement of the bowels, making stools easier to pass. While it doesn't specify an exact timeframe, the unwanted effects often improve as your body adjusts to the new medicine, which suggests a period of adjustment in the initial days of treatment.

What should I do if I am already taking other medications for constipation or other conditions?

Before you start taking prucalopride, it's very important to inform your doctor about any other medicines you are taking. This includes both prescription medicines and those you can buy without a prescription, as well as herbal and complementary medicines. Your doctor needs this information to ensure prucalopride is suitable for you.

Is there a specific time of day I should take prucalopride?

You can take prucalopride at a time of day that suits you, whether before or after food. However, it is recommended to take your doses at the same time each day. This routine can help you remember to take your medicine regularly.

How long will I need to take prucalopride?

The article does not specify a duration for taking prucalopride. It mentions that you should keep any regular appointments with your doctor so they can check on your progress, suggesting treatment length will be decided by your doctor based on your individual needs and response.

What lifestyle changes are important to support my treatment with prucalopride?

While taking prucalopride, it's still important to maintain a healthy lifestyle to support healthy bowel function. This includes eating a diet rich in fibre (like wholegrain breads, cereals, bran, fruit, and green leafy vegetables), drinking several glasses of water daily, and getting daily exercise.

Can I stop taking prucalopride once my constipation improves?

The article advises to keep regular appointments with your doctor so they can check your progress. It does not provide guidance on stopping the medication, implying that any decision about ending treatment should be made in consultation with your doctor.

What if I experience unusual symptoms that are not listed as common side-effects?

If you experience any other symptoms that you believe might be due to prucalopride tablets, you should speak with your doctor or pharmacist for further advice. The manufacturer's leaflet supplied with your medicine will also contain a full list of possible side-effects.

Vidare läsning och referenser

Fortsätt läsa nedan

About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 18 Sept 2026
  • 19 Sept 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
flu eligibility checker

Fråga, dela, anslut.

Bläddra i diskussioner, ställ frågor och dela erfarenheter inom hundratals hälsorelaterade ämnen.

Anmäl dig till Patientens nyhetsbrev

Din veckovisa dos av tydliga, pålitliga hälsoråd - skrivna för att hjälpa dig känna dig informerad, självsäker och i kontroll.

Vänligen ange en giltig e-postadress

By subscribing you accept our Sekretesspolicy. Du kan avsluta prenumerationen när som helst. Vi säljer aldrig dina uppgifter.