Alendronsyra för osteoporos
Fosamax, Binosto
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 7 Aug 2023
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It is very important that you carefully follow the instructions for taking alendronic acid - otherwise it can cause irritation and damage to your throat. You will find full instructions on the information leaflet provided with your medicine. See also the section called 'Taking alendronic acid', below.
If you buy any medicines, make sure your pharmacist knows that you are taking a bisphosphonate, as some medicines will prevent alendronic acid from working properly.
Good dental hygiene is particularly important with this treatment - this means that you must brush your teeth regularly, and have routine dental check-ups.
Överblick
Alendronic acid is a bisphosphonate medicine for treating osteoporosis.
It slows down bone loss, increasing bone density and reducing fracture risk.
Take it with plain water, standing or sitting upright, before food or other drinks.
Do not lie down for 30 minutes after taking it.
Tell your doctor if you have swallowing difficulties, stomach problems, or kidney issues.
See your doctor if you develop heartburn, pain in your thigh or jaw, or black stools.
About alendronic acid
Typ av medicin | Bisphosphonate |
Används för | Osteoporos |
Även kallad | Sodium alendronate; Binosto®; Fosamax® Once Weekly |
Tillgänglig som | Tablets, soluble tablets and oral liquid |
Osteoporos is a bone disease which causes your bones to become brittle and fragile, making them prone to breaks and fractures. During our lifetime, old bone tissue is constantly being broken down and replaced by new bone. After the age of about 30-35 years, our bone begins to lose density because old bone is lost faster than new bone can replace it. Women in particular have an increased risk of developing osteoporosis, as they lose bone material rapidly after the menopause.
Alendronic acid belongs to a group of medicines known as bisphosphonates. These medicines slow down the rate at which old bone is lost. As your body continues to make new bone, this leads to an overall increase in bone density. This reduces your risk of broken bones and fractures. You may be prescribed alendronic acid to take once a day (10 mg strength tablets), or more commonly, once a week (70 mg strength tablets/medicine).
In the brands of tablets called Fosavance® and Bentexo®, alendronic acid is combined with a vitamin called colecalciferol (also known as vitamin D3). Colecalciferol helps your bones absorb calcium. Because our bodies naturally make colecalciferol from exposure to sunlight and also absorb small amounts from foods such as oily fish, many people do not need supplements of this vitamin. However, as we get older, the amount of colecalciferol we absorb naturally may reduce. This brand of tablet is suitable for people requiring supplements of colecalciferol alongside alendronic acid.
Before taking alendronic acid
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking alendronic acid it is important that your doctor knows:
Om du är gravid eller ammar.
If you have ever had any difficulties swallowing.
If you have had a stomach ulcer, stomach bleeding or any surgery on your upper digestive system within the previous year.
If you are due to have any dental treatment in the near future, or if you have inte recently had a dental check-up.
Om du har några problem med hur dina njurar fungerar.
If you are unable to sit upright for at least 30 minutes.
If you have been told you have low amounts of calcium in your blood.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take alendronic acid
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about alendronic acid and will provide you with a full list of the side-effects which you may experience from taking it.
If you are taking alendronic acid 10 mg tablets, take one tablet daily. If on any day you forget to take a dose, just take your tablet on the next day as usual. Do not take a double dose to make up for a missed dose.
If you are taking tablets containing alendronic acid 70 mg (brands Fosamax® Once weekly and Fosavance®), take one tablet once a week. You must take your dose on the same day of each week, so choose a day that best suits your routine. If you forget to take a dose on your usual day, take it on the following morning and then continue taking it on your chosen day when your next dose is due.
If you are taking alendronic acid 70 mg in 100 ml oral liquid medicine, take 100 ml (one unit) once a week. Take it on the same day of each week. If you forget to take a dose on your usual day, take it on the following morning and then continue taking it on your chosen day when your next dose is due.
Taking alendronic acid
It is important that you take alendronic acid in the correct way, as otherwise it can cause irritation and damage as it is swallowed:
Take the tablet/medicine first thing after getting up in the morning. Take it before you eat any food or have anything to drink other than water.
You must drink a large glassful of plain water (not mineral water) as you take your dose. If you are taking tablets, swallow the tablet whole - you must inte chew, break, or crush alendronic acid tablets.
It is important that you take your dose while you are standing or sitting in an upright position.
Continue to sit or stand upright for 30 minutes after taking your dose - you must inte lie down during this time.
Do not have anything to eat or drink (other than plain water), or take any other medicines during the 30 minutes after taking a dose.
Få ut det mesta av din behandling
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. It is likely you will need to have regular blood tests during this treatment.
If you are taking other medicines, wait at least 30 minutes after taking alendronic acid before taking your other medicines. If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take. This is because mineral supplements, iron preparations, and some indigestion remedies reduce the amount of alendronic acid which your body absorbs. This can make your treatment less effective.
Good dental hygiene is particularly important while you are taking alendronic acid - brush your teeth regularly and remember to have routine dental check-ups. Tell your dentist that you are taking alendronic acid, as some dental treatments may not be recommended for you.
Eating a well-balanced diet and taking regular exercise can help your bones stay strong. Remember to follow any exercise or dietary advice that your doctor gives to you.
Chemicals from tobacco can get into your bloodstream and can affect your bones, making bone loss worse. If you are a smoker, you should try to quit if possible. Ask your doctor or pharmacist for advice on how to stop smoking.
Can alendronic acid cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with alendronic acid. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common alendronic acid side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Indigestion, abdominal pain, bloating, wind (flatulence), acid regurgitation, feeling sick (nausea) | Make sure you carefully follow the directions for taking alendronic acid and remain standing or sitting for at least half an hour afterwards. If the symptoms get worse, let your doctor know straightaway |
Diarré | Drink plenty of water to replace lost fluids |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water a day |
Headache, muscle or joint pain | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the pain continues, let your doctor know |
Feeling dizzy, itching | Om det är besvärligt, prata med din läkare |
Less common, but possibly serious, side-effects | What should I do if I experience this? |
Heartburn, pain or difficulty when you swallow | Stop taking alendronic acid and speak with your doctor as soon as possible - these can be signs of severe throat irritation |
Pain in your thigh, hip, or groin | Speak with your doctor as soon as possible - these can be signs of a thighbone fracture |
A loose tooth, or jaw pain with swelling or numbness | Speak with your doctor as soon as possible - these can be signs of a problem called osteonecrosis of the jaw |
Black or bloody stools | Speak with your doctor as soon as possible - this can be a sign of an ulcer |
Ear pain, discharge from an ear, ear infection | These could be signs of a problem called osteonecrosis of the ear. Speak with your doctor straightaway |
Om du upplever några andra symtom som du tror kan bero på medicinen, tala med din läkare eller apotekare för vidare råd.
How to store alendronic acid
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Vanliga frågor
What is osteonecrosis of the jaw and how can I prevent it while taking alendronic acid?
Osteonecrosis of the jaw is a less common but potentially serious side-effect indicated by a loose tooth, jaw pain with swelling, or numbness. Good dental hygiene is particularly important while taking alendronic acid. You should brush your teeth regularly, have routine dental check-ups, and tell your dentist that you are taking alendronic acid as some dental treatments may not be recommended. If you experience any of these symptoms, speak with your doctor as soon as possible.
Can I take alendronic acid if I have difficulty swallowing?
Before you start taking alendronic acid, it is important to inform your doctor if you have ever had any difficulties swallowing. Your doctor will then be able to determine if alendronic acid is suitable for you.
Are there any specific dietary considerations while taking alendronic acid?
To get the most from your treatment, it is recommended to eat a well-balanced diet. Specifically, mineral supplements, iron preparations, and some indigestion remedies can reduce the amount of alendronic acid your body absorbs, making the treatment less effective. It's important to wait at least 30 minutes after taking alendronic acid before taking any other medicines or supplements, and to check with a pharmacist about suitability of over-the-counter medicines.
What should I do if I experience heartburn or pain when swallowing while on alendronic acid?
Heartburn, or pain or difficulty when you swallow, can be signs of severe throat irritation. If you experience these symptoms, you should stop taking alendronic acid and speak with your doctor as soon as possible.
What is the advice for taking alendronic acid if I am a smoker?
Chemicals from tobacco can enter your bloodstream and affect your bones, potentially worsening bone loss. If you are a smoker, it is recommended that you try to quit. You can ask your doctor or pharmacist for advice on how to stop smoking.
Can I take alendronic acid if I have kidney problems?
If you have any problems with the way your kidneys work, it is important to inform your doctor before you start taking alendronic acid. They will need to know this to decide if the medicine is suitable for you.
Vidare läsning och referenser
- Manufacturer's PIL, Fosamax® Once Weekly 70 mg Tablets; Organon Pharma (UK) Limited, The electronic Medicines Compendium. Dated April 2022.
- Manufacturer's PIL, Fosavance® Tablets; Organon Pharma (UK) Limited, The electronic Medicines Compendium. Dated October 2021.
- Manufacturer's PIL, Binosto® 70 mg effervescent tablets; Internis Pharmaceuticals Ltd, The electronic Medicines Compendium. Dated October 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 6 Aug 2026
7 Aug 2023 | Senaste versionen

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