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Darifenacin tablets

Emselex

Take one tablet every day. There are two strengths of tablet available - 7.5 mg and 15 mg. Your doctor will tell you which strength is right for you.

The most common side-effects are dry mouth and constipation.

At a glance

  • Darifenacin is a medicine for urinary urgency, frequency, and incontinence.

  • It works by stopping sudden bladder muscle contractions and increasing bladder capacity.

  • Take tablets whole with water, at the same time each day, with or without food.

  • Common side effects include constipation and dry mouth.

  • Avoid chewing or crushing the prolonged-release tablets.

  • Discuss all other medicines and existing health conditions with your doctor.

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About darifenacin

Typ av medicin

An antimuscarinic medicine

Används för

Symptoms of urinary urgency, frequency and incontinence

Även kallad

Emselex®

Tillgänglig som

Prolonged-release tablets

Darifenacin is prescribed to treat urinary symptoms such as urgency, frequency and incontinence. Urinary urgency occurs when you have a sudden and urgent need to pass urine. If you need to take more trips to the toilet than normal, this is called urinary frequency. If you leak urine before you go to the toilet, this is called incontinence.

There are several different causes of these urinary symptoms, such as weakened pelvic floor muscles, problems causing your bladder muscles to contract too much or too early, or something causing an obstruction. Sometimes the cause of these symptoms is unknown.

Darifenacin works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. This helps to control the release of urine and eases your symptoms.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking darifenacin it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have a heart condition, such as an unusual heart rhythm, problems with the blood vessels in your heart, or heart failure.

  • If you have any problems with the way your liver works, or any problems with your prostate gland.

  • If you have any of the following conditions: increased pressure in your eye (glaucoma); hiatus hernia; an overactive thyroid gland; high blood pressure; a condition causing muscle weakness, called myasthenia gravis.

  • If you have a condition which could cause a blockage in your stomach, bowel or urinary tract.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

Fortsätt läsa nedan

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about darifenacin and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the tablets exactly as your doctor tells you to. The usual starting dose is one 7.5 mg tablet every day. After two weeks of treatment your doctor may increase your dose to one 15 mg tablet every day if it is considered necessary.

  • Try to take the tablet at the same time of day each day, as this will help you to remember to take your doses regularly. You can take darifenacin either before or after meals. Swallow the tablet with a drink of water. The tablets have been specially made to release darifenacin evenly over the day, so it is important that you swallow the tablet whole - do not chew or crush it before you swallow.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose but make sure you take the dose due on that day. Do not take two doses together to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.

  • Drinks containing caffeine (for example, tea, coffee, hot chocolate and cola) may make your symptoms worse. This is because caffeine increases urine flow (it is a natural diuretic) and will make you want to pass urine. If you drink a lot of caffeine-containing drinks, consider switching to decaffeinated alternatives.

  • Try to maintain a normal life as much as possible with regard to drinking and visiting the toilet. However, drinking late at night may mean your sleep is disturbed by the desire to get up and go to the toilet, so you may want to avoid drinking too much during the evening.

  • Your doctor may suggest that you do some pelvic floor exercises to strengthen the muscles around the underside of your bladder. These can help to improve your symptoms.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with darifenacin. This is because some medicines (particularly antihistamines) can increase the chance that you will experience unwanted effects such as a dry mouth, constipation and blurred vision.

Fortsätt läsa nedan

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with darifenacin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common darifenacin side-effects (these affect more than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Förstoppning

Try to eat a well-balanced diet and drink several glasses of water each day

Torr mun

Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller

Common darifenacin side-effects (these affect fewer than 1 in 10 people)

Vad kan jag göra om jag upplever detta?

Feeling sick (nausea), indigestion, tummy (abdominal) pain

Eat simple meals - avoid rich or spicy foods

Huvudvärk

Ensure you are drinking the recommended amount of water each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Dry nose, dry eyes

If either of these become troublesome, speak with your doctor

Less common side-effects: feeling sleepy, blurred vision

Kör inte och använd inte verktyg eller maskiner när du är påverkad

If you experience any other symptoms which you think may be due to the tablets, please speak with your doctor or pharmacist for further advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vanliga frågor

What is the primary role of darifenacin in treating urinary issues?

Darifenacin works by stopping sudden contractions of the bladder muscles. It also helps to increase the amount of urine your bladder can hold, which in turn helps to control the release of urine and lessens your symptoms of urgency, frequency, and incontinence.

How long does it usually take before I might see an improvement in my symptoms after starting darifenacin?

The article states that the usual starting dose is one 7.5 mg tablet daily, and your doctor may increase it to one 15 mg tablet daily after two weeks if necessary. This suggests that your doctor will be assessing your progress within this timeframe, and improvements or adjustments can be made after about two weeks.

Are there any specific drinks I should avoid or reduce while taking darifenacin?

Yes, drinks that contain caffeine, such as tea, coffee, hot chocolate, and cola, might make your urinary symptoms worse. This is because caffeine acts as a natural diuretic, increasing urine flow. You might consider switching to decaffeinated alternatives if you consume a lot of these drinks.

Can I take darifenacin with other medications that I buy without a prescription?

It's important to inform your doctor about all medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. Also, if you buy any new medicines, it's advisable to check with a pharmacist to ensure they are suitable to take with darifenacin, as some can increase the chance of side-effects such as dry mouth or blurred vision.

What should I do if I accidentally chew or crush my darifenacin tablet?

Darifenacin tablets are designed to release the medicine gradually over the day. Therefore, it's important to swallow the tablet whole without chewing or crushing it. If you accidentally chew or crush it, the medicine may not work as intended, but the article does not provide specific instructions for this scenario other than to swallow it whole.

Can darifenacin affect my ability to drive or operate machinery?

Yes, less common side-effects of darifenacin include feeling sleepy and blurred vision. If you experience either of these, you should not drive or use tools or machines while affected.

Vidare läsning och referenser

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 20 Jul 2027
  • 20 Jul 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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