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Flutamide - an anti-androgen for men

Treatment with flutamide will be started by a specialist doctor.

The usual dose is one tablet three times daily.

Remember to keep your regular appointments with your doctor and clinic so that your progress can be monitored.

Överblick

  • Flutamide is an anti-androgen medicine used to treat prostate cancer.

  • It comes as tablets that are usually taken three times a day.

  • Flutamide works by blocking male hormones which helps slow down cancer growth.

  • You will need regular blood tests to check your liver function whilst taking flutamide.

  • Contact your doctor straightaway if you have symptoms of liver problems like dark urine or yellow skin.

About flutamide

Typ av medicin

An anti-androgen

Används för

Prostatacancer

Tillgänglig som

Tabletter

Flutamide belongs to a group of medicines known as anti-androgens. This means that it blocks the actions of male sex hormones called androgens. It also reduces the amount of male hormones (such as testosterone) that your body produces.

I prostatacancer, the cancer cells need the male hormone testosterone to grow and multiply well. Hormone treatments like flutamide block the effect of testosterone on prostate cancer cells. This slows down the growth of the cancer. Flutamide also helps to reduce symptom 'flares' and side-effects from other treatments which may be used for the cancer, or following surgery.

Before taking flutamide

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking flutamide it is important that your doctor knows:

  • If you have any problems with the way your liver works.

  • Om du har en hjärtsjukdom.

  • Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel som kan köpas utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take flutamide

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about flutamide and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take the tablets exactly as your doctor tells you to. Your dose will be printed on the label of the pack of tablets to remind you about what the doctor said to you. It is usual to take one tablet three times a day.

  • You can take flutamide tablets either with or without food. Taking the tablet with a drink of water will help you to swallow it.

  • Try to take the tablets at the same times of day each day. This will help you to remember to take your doses regularly.

  • If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • Please keep your regular appointments with your doctor so that your progress can be monitored. Your doctor will want you to have some blood tests from time to time to check that your liver is staying healthy.

  • Your doctor will recommend that you do not drink much alcohol while you are on flutamide.

  • Treatment with flutamide is often long-term. You should continue to take the tablets regularly unless you are told otherwise by your doctor.

Can flutamide cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with flutamide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common flutamide side-effects (these affect more than 1 in 10 men)

Vad kan jag göra om jag upplever detta?

Breast swelling or tenderness (possibly with a discharge)

If this becomes troublesome, speak with your doctor

Common flutamide side-effects (these affect fewer than 1 in 10 men)

Vad kan jag göra om jag upplever detta?

Känna sig illamående (nausea) eller kräkas (vomiting), diarré

Eat simple meals - avoid fatty or spicy foods

Tiredness, difficulty sleeping, increased appetite

Om något av dessa blir besvärligt, tala med din läkare

Liver problems (for the symptoms please see below)

Contact your doctor straightaway

Viktigt: if you notice any of the following you should contact your doctor straightaway as it could be a sign of a problem with your liver:

  • Dark urine or light-coloured stools.

  • Att vara sjuk (kräkas)

  • Pain in your tummy (abdomen).

  • Any yellowing of your skin or the whites of your eyes (jaundice).

  • Itchy skin or unexplained bruising.

  • Loss of appetite.

  • Any unexplained flu-like symptoms.

  • Feeling unusually tired or generally unwell.

If you experience any other symptoms which you think may be due to the tablets, please speak with your doctor or pharmacist for further advice.

How to store flutamide

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Om du köper några läkemedel, kontrollera med en apotekare att de är säkra att ta tillsammans med dina förskrivna läkemedel.

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

symptomkontroll

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

How does flutamide work to slow down prostate cancer?

Flutamide works in two main ways. Firstly, it blocks the actions of male sex hormones, specifically androgens, on prostate cancer cells. Secondly, it reduces the overall amount of male hormones, such as testosterone, that your body produces. Since prostate cancer cells need testosterone to grow and multiply, blocking and reducing these hormones slows the cancer's growth.

Can flutamide help with side-effects from other prostate cancer treatments?

Yes, flutamide can help to reduce symptom 'flares' and side-effects that might arise from other treatments used for prostate cancer, or following surgery.

Why do I need blood tests while taking flutamide?

Regular blood tests are important while you are taking flutamide. Your doctor will use these tests to monitor your progress and specifically to check that your liver is remaining healthy, as liver problems can be a side-effect of this medication.

What should I do if I notice my urine is dark or stools are light-coloured?

If you notice dark urine or light-coloured stools, you should contact your doctor straightaway. These could be signs of a problem with your liver, which needs immediate medical attention.

Is it okay to take other medicines, including over-the-counter ones, with flutamide?

Before you start taking flutamide, it is important to inform your doctor about all other medicines you are taking. This includes any medicines bought without a prescription, as well as herbal and complementary medicines, to ensure they are safe to take together.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 14 Apr 2028
  • 14 Apr 2025 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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