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Sunitinib kapslar

Sutent

Sunitinib is taken once daily. You may be asked to take it every day, or to take it for four weeks followed by two treatment-free weeks.

It may colour your urine - this is harmless.

Good dental hygiene is particularly important with this treatment - brush your teeth regularly, and have routine dental check-ups.

Överblick

  • Sunitinib is an anti-cancer medicine used to treat certain cancers, including advanced kidney cancer.

  • It works by slowing down the growth and spread of cancer cells.

  • Take capsules once a day, usually at the same time each day, with water.

  • Read the manufacturer's leaflet for full information before you start treatment.

  • Do not drink grapefruit juice while taking sunitinib.

  • Tell your doctor if you experience jaw pain, swelling, or numbness.

  • Do not get pregnant while taking sunitinib; discuss contraception with your doctor.

About sunitinib

Typ av medicin

An anti-cancer medicine (a protein kinase inhibitor)

Används för

Cancer

Även kallad

Sutent®

Tillgänglig som

Kapslar

Sunitinib is a medicine which is given to treat certain cancers. It is usually prescribed after other treatments have been tried first, or if other treatments are not suitable. The type of cancers that it is taken for are kidney cancer that has progressed or spread into other areas of the body; a stomach and bowel cancer called gastrointestinal stromal tumour (GIST); and cancers which have spread from the pancreas.

In cancer, certain cells in the body grow and multiply in a way that is 'out of control'. Medicines like sunitinib slow down the way cancer cells grow and spread. Sunitinib belongs to a group of anti-cancer medicines known as protein kinase inhibitors. These work by blocking chemical messengers (called kinases) which send signals to cells to grow.

Before taking sunitinib

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking sunitinib it is important that your doctor knows:

  • If you have an infection or feel particularly unwell.

  • If you have a heart condition or an unusual heart rhythm.

  • If you have high blood sugar levels (diabetes mellitus) or have ever had very low blood sugar levels (hypoglycaemia).

  • If you have high blood pressure or blood vessel disease.

  • Om du är gravid eller ammar.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take sunitinib

  • Before you start the treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside the pack of capsules. These will give you more information about sunitinib and will provide a full list of the side-effects which you may experience from taking it.

  • Sunitinib will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your dose will depend upon the type of cancer you have. It is important that you take the capsules exactly as you are told to. There are a number of different strengths of capsule and your dose may be made up of more than one strength. Sunitinib is taken once each day - try to take your doses at the same time of day each day. You may be told to take the capsules every day, or for treatment cycles of four weeks followed by two treatment-free weeks. The directions for taking the capsules will be printed on the label of the pack to remind you what your doctor has told you to do, but if you have any concerns or questions, you should contact your doctor or hospital clinic for further advice.

  • Swallow the capsules with a drink of water. You can take sunitinib capsules before or after meals.

  • Do not drink grapefruit juice while you are on sunitinib. This is because a chemical in grapefruit juice can interfere with the amount of sunitinib in your bloodstream.

  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, take the dose that is due but leave out the forgotten dose. Do not take two doses on the same day to make up for a missed dose.

Få ut det mesta av din behandling

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during treatment.

  • Sunitinib can cause your urine to look a different colour - this is harmless and nothing to be concerned about.

  • Sunitinib could cause your blood sugar level to go too low (hypoglycaemia). Signs this could be happening include weakness, trembling, a racing pulse, sweating and cold, clammy skin. Drinking or eating something sugary will help raise your blood sugar level, but also contact your doctor or pharmacist for advice. If you have diabetes your doctor may need to adjust your treatment and you may need to test your blood sugar levels more regularly.

  • If you buy or take any other medicines, check with a pharmacist that they are suitable to take alongside sunitinib.

  • Good dental hygiene is particularly important while you are taking these capsules - brush your teeth regularly and remember to have routine dental check-ups. Tell your dentist that you are taking sunitinib, as some dental treatments may not be recommended for you.

  • It is important that you do not get pregnant while you are taking sunitinib. If this could be a possibility for you, make sure you discuss with your doctor which types of contraception are suitable for you and your partner.

Can sunitinib cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with sunitinib. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common sunitinib side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Feeling sick (nausea) or being sick (vomiting), indigestion, abdominal discomfort

Stick to simple foods - avoid rich or spicy foods. Let your doctor know if this continues

Diarrhoea or constipation

Drink plenty of water

Headache, aches and pains

Ask your doctor or pharmacist to recommend a suitable painkiller

Increased number of infections, bleeding problems such as nosebleeds

Speak with your doctor for advice

Skin colour changes, dry or cracked skin, rash or soreness particularly on the hands or feet, sore mouth, changes in the way things taste, feeling short of breath, cough

Om det är besvärligt, prata med din läkare

A loose tooth, jaw pain with swelling or numbness

Speak with your doctor as soon as possible - these may be signs of a problem called osteonecrosis of the jaw

Heart problems (let your doctor know straightaway if you get chest pain), high bloood pressure, changes to some blood tests

Your doctor will regularly check for these

If you experience other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for further advice.

How to store sunitinib

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

  • Please return any unused or unwanted capsules to your clinic or pharmacy to destroy.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

If you are due to have an operation or any other medical treatment, tell the person carrying out the treatment which medicines you are taking.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

symptomkontroll

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

What is the specific role of protein kinase inhibitors like sunitinib in treating cancer?

Sunitinib is a type of anti-cancer medicine known as a protein kinase inhibitor. These medicines work by blocking specific chemical messengers, called kinases, which are responsible for sending signals to cancer cells that tell them to grow and multiply. By blocking these signals, sunitinib helps to slow down the growth and spread of cancer cells.

Is it normal for my urine to change colour while taking sunitinib?

Yes, sunitinib can cause your urine to look a different colour. This is a harmless effect and there is no need to be concerned about it.

Why is good dental hygiene particularly important when taking sunitinib?

Maintaining good dental hygiene is especially important while you are taking sunitinib capsules. You should brush your teeth regularly and attend routine dental check-ups. It is also crucial to inform your dentist that you are taking sunitinib, as some dental treatments might not be recommended for you due to how the medicine works.

What should I do if I notice changes in my skin, such as dryness or a rash, while on sunitinib?

If you experience troublesome skin changes like dryness, cracked skin, a rash, or soreness, particularly on your hands or feet, you should speak with your doctor for advice. These are common side-effects of sunitinib.

What should I do if my jaw feels painful, swollen, or numb while taking sunitinib?

If you experience jaw pain accompanied by swelling or numbness, or if you have a loose tooth, you should speak with your doctor as soon as possible. These could be signs of a potentially serious problem called osteonecrosis of the jaw, which occasionally can occur with this medicine.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

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