Tadalafil för pulmonell hypertension
Adcirca, Talmanco
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 7 Nov 2022
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When you collect your prescriptions, check that you have been given the same brand of tablets as before. If the appearance is not the same as usual, speak with your doctor or pharmacist.
The usual dose is 40 mg daily (taken as two 20 mg tablets).
The most common side-effects are headache, flushing, nasal congestion, stomach upset, and muscle aches and pains.
Överblick
Tadalafil is a medicine used to treat pulmonary hypertension in adults.
It is a vasodilator that helps relax blood vessels in the lungs to reduce blood pressure.
Take tablets exactly as your doctor tells you, usually two 20 mg tablets once daily.
Do not drink grapefruit juice while taking tadalafil.
Common side-effects include headache, muscle aches, flushing, and indigestion.
Seek medical attention for chest pains, sudden vision/hearing loss, or erections lasting over four hours.
About tadalafil for pulmonary hypertension
Typ av medicin | Vasodilator antihypertensive medicine |
Används för | Pulmonary hypertension in adults |
Även kallad | Adcirca®; Talmanco® |
Tillgänglig som | Tabletter |
Primary pulmonary hypertension is a rare condition where there is too high a blood pressure in the blood vessels that supply your lungs from your heart.
Tadalafil relaxes the muscle cells in the walls of the blood vessels to your lungs, allowing them to become wider (dilated). This reduces the pressure in these blood vessels and allows blood to flow more easily through them. In turn, this increases the supply of blood to your lungs and improves your ability to do physical activities. It will be prescribed for you by a specialist doctor.
Tadalafil can also be prescribed for men with two completely different conditions - please see the separate medicine leaflet called Tadalafil för erektil dysfunktion eller förstorad prostata if you have been prescribed tadalafil tablets for either of these reasons.
Before taking tadalafil
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking tadalafil it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any other heart problem or blood vessel condition.
If you have had an eye condition causing a loss of vision.
If you have problems with the way your liver works, or if you have problems with the way your kidneys work.
If you have recently had a heart attack.
If you have any disease, injury or deformity of your penis.
If you have sickle cell disease.
If you have ever had bone marrow cancer or leukaemia.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines, and recreational drugs.
Om du någonsin har haft en allergisk reaktion mot en medicin.
How to take tadalafil
Before you take tadalafil, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about the tablets and will provide you with a full list of the side-effects which you could experience from taking them.
Take the tablets exactly as your doctor tells you to. The usual dose is two 20 mg tablets taken together, once daily.
Unless your doctor tells you otherwise, you can generally take tadalafil at a time of day that suits you. You should, however, try to take your doses at the same time of day, each day.
You can take tadalafil either with or without food. Swallow the tablets with a drink of water.
If you forget to take a dose, take it as soon as you remember as long as it is still within eight hours of the time you should have taken it. If when you remember, it is more than eight hours later, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Få ut det mesta av din behandling
It is recommended that you do not drink grapefruit juice with tadalafil. This is because there is a chemical in grapefruit juice which may increase the amount of tadalafil in your bloodstream. This could make side-effects more likely.
Försök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you are due to have an operation or some other medical treatment, it is important that you tell the person carrying out the treatment that you are taking tadalafil.
Each time you collect a new supply of tablets from the pharmacy, make sure it looks to be the same as you have had before. If you are unsure, ask your pharmacist to check for you.
Om du köper några läkemedel, kontrollera med en apotekare att de är lämpliga att ta tillsammans med dina andra läkemedel.
Can tadalafil cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with tadalafil. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Very common tadalafil side-effects (these affect more than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Headache, muscle aches and pains | Ask your pharmacist to recommend a suitable painkiller. If the aches continue, let your doctor know |
Facial flushing, nose or throat symptoms | If troublesome, speak with your doctor for advice |
Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) discomfort | Håll dig till enkla måltider - undvik fet eller kryddstark mat |
Common tadalafil side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Feeling faint or dizzy, blurred vision | Do not drive and do not use tools or machines until your reactions/vision have returned to normal. If the problem with your eyesight starts suddenly, speak with your doctor |
Nosebleeds, the feeling of having a 'thumping heart' (palpitations), increased menstrual bleeding | If any become troublesome, speak with your doctor for advice |
Viktigt: if you experience any of the following, contact a doctor for medical attention straightaway:
An allergic-type reaction such as a rash or swelling around your face.
Chest pains
A sudden loss of vision or hearing
An erection lasting for more than four hours.
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store tadalafil
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can I take tadalafil if I am also taking other prescription medications?
You should always inform your doctor about all medicines you are taking, including those bought without a prescription, herbal remedies, complementary medicines, and recreational drugs, before starting tadalafil. This is because some medicines might not be suitable to take together, or extra care might be needed.
What should I do if I notice that my new supply of tadalafil tablets looks different from my previous ones?
Each time you get a new supply of tablets from the pharmacy, you should check to make sure they look the same as what you've had before. If you are unsure or have any concerns about the appearance of your medication, ask your pharmacist to check for you.
Are there any specific foods or drinks I should avoid while taking tadalafil?
It is recommended that you do not drink grapefruit juice when taking tadalafil. Grapefruit juice contains a chemical that can increase the amount of tadalafil in your bloodstream, potentially making side-effects more likely to occur.
How often do I need to see my doctor while taking tadalafil?
It is important to keep your regular appointments with your doctor while on tadalafil. These appointments allow your doctor to monitor your progress and ensure the treatment is working effectively for you.
What is the purpose of tadalafil in treating pulmonary hypertension?
Tadalafil is used to treat pulmonary hypertension by relaxing the muscle cells in the walls of the blood vessels leading to your lungs. This relaxation causes the blood vessels to widen, which in turn reduces the pressure within them and helps blood flow more easily. This process increases blood supply to your lungs and improves your ability to perform physical activities.
Vidare läsning och referenser
- Manufacturer's PIL, Adcirca® 20 mg film-coated tablets; Eli Lilly and Company Limited, The electronic Medicines Compendium. Dated January 2021.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Helen Allen, MPharm
Apotekare, Medicinsk Författare
MPharm
Helen Allen kvalificerade sig som apotekare 1979 och tillbringade 3 år som författare av läkemedelsinformationsbroschyrer för EMIS.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 6 May 2027
7 Nov 2022 | Senaste versionen
9 Jul 2013 | Ursprungligen publicerad
Författad av:
Helen Allen, MPharm

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