Linagliptin-tabletter för diabetes

Trajenta

Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 5 apr 2025

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Linagliptin will help to reduce blood sugar (glucose) levels in people with type 2 diabetes. It is often taken alongside other antidiabetic medicines.

Remember to follow any advice you have been given about your diet and taking exercise.

Side-effects are uncommon but could include cough and cold-like symptoms. A rare side-effect is persistent or severe tummy pain - you should let your doctor know about this if it happens to you.

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About linagliptin

Typ av medicin	An antidiabetic medicine, known as a DPP-4 inhibitor or an incretin enhancer
Används för	Adults with type 2 diabetes mellitus
Även kallad	Trajenta® Combination brands: Jentadueto® (linagliptin with metformin); Glyxambi® (linagliptin with empagliflozin)
Tillgänglig som	Tabletter

Insulin is a hormone which is made naturally in your body. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called diabetes (diabetes mellitus).

People with diabetes need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like linagliptin are given alongside the changes in diet.

Linagliptin works in part by increasing the amount of insulin produced by your body, which then controls the level of sugar in your blood. It also reduces the amount of a substance called glucagon being produced by your pancreas. Glucagon causes your liver to produce more sugar; so, by reducing the amount of glucagon in your body, this also helps to reduce the levels of sugar in your blood.

For more information on how antidiabetic medicines like linagliptin work, see the separate leaflet called Typ 2-diabetesbehandling.

Before taking linagliptin tablets

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking linagliptin it is important that your doctor knows:

Om du är gravid eller ammar.
Om du har några problem med hur dina njurar fungerar.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take linagliptin tablets

Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about linagliptin tablets and will provide you with a full list of the side-effects which you may experience from taking them.
Take linagliptin tablets exactly as your doctor tells you to. Your dose will be on the label of the pack to remind you about what the doctor said to you.
If you are taking a brand of linagliptin tablets called Trajenta®, the dose is 5 mg (one tablet) daily. You can generally take the tablet at a time of day to suit you, but it is best to take your doses at the same time of day each day. You can take these tablets either with or without food.
If you have been prescribed a combination tablet of linagliptin with metformin (Jentadueto® brand) you should take one tablet twice a day. Take the tablet after you have eaten a meal or with a snack, as this will help to reduce the chance of an upset stomach. There are two strengths of Jentadueto® tablet - both strengths contain the same amount of linagliptin but the amount of metformin differs. You will be prescribed the strength of tablet that fits with your current metformin dose.
If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

Det är viktigt att du håller dina regelbundna läkar- och klinikbesök. Detta är så att dina framsteg kan övervakas. Du kommer att behöva regelbundna kontroller hos en ögonklinik och en fotklinik samt hos din läkare och diabetesklinik.
Din läkare kan rekommendera att du regelbundet testar socker (glukos) i ditt blod eller urin för att kontrollera att din diabetes är under kontroll. Din läkare eller diabetessköterska kommer att visa dig hur du gör detta.
Om du har fått råd från din läkare om förändringar i din kost, att sluta röka eller att motionera regelbundet, är det viktigt att du följer de råd du har fått.
Drick inte alkohol, eftersom det kan påverka kontrollen av ditt blodsocker. Fråga din läkare om du behöver ytterligare råd om detta.
Om du är förare bör du vara extra försiktig, eftersom din förmåga att koncentrera dig kan påverkas om din diabetes inte är välkontrollerad. Du kan bli rekommenderad att kontrollera ditt blodsockernivå innan du reser och att ha ett mellanmål med dig på långa resor.
Konsultera din läkare innan du börjar med någon ny fysisk aktivitet, eftersom detta kan påverka dina blodsockernivåer och du kan behöva kontrollera dina blod- eller urinnivåer mer regelbundet.
Make sure you know what it feels like if your blood sugar is low. This is known as hypoglycaemia, or a 'hypo'. Although linagliptin is unlikely to cause low blood sugar, other medicines that you are taking for diabetes alongside it may. The first signs of hypoglycaemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy.
If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and that you are taking linagliptin.
If you get unusually thirsty, pass urine more frequently than normal, and feel very tired, you should let your doctor know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.
Treatment for diabetes is usually lifelong. Continue to take linagliptin tablets unless you are advised otherwise by your doctor.

Can linagliptin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with linagliptin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Linagliptin side-effects (these affect fewer than 1 in 100 people)	Vad kan jag göra om jag upplever detta?
Cough, nose and throat symptoms; rash	Om något av dessa blir besvärligt, tala med din läkare för råd

Viktigt: this medicine can cause persistent and severe tummy pain in a few people. If this happens to you, you should speak with your doctor as soon as possible as it can be a symptom of an inflamed pancreas (pankreatit).

Viktigt: Metformin can lower the level of vitamin B12 in your body. Long-term treatment may lead to vitamin B12 deficiency, especially at higher doses and in people with other risk factors. Your doctor may test your blood to check for low vitamin B12 levels, which can be corrected by taking a vitamin supplement. Speak to your doctor if you notice any signs of low vitamin B12 levels including extreme tiredness, a sore and red tongue, mouth ulcers, pins and needles or pale or yellow skin

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

How to store linagliptin tablets

Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå omedelbart till akutmottagningen på ditt lokala sjukhus. Ta med förpackningen, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable to take with your prescribed medicines.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

Vanliga frågor

What should I do if I notice signs of a low vitamin B12 level while taking linagliptin with metformin?

If you are taking a combination tablet of linagliptin with metformin (brand Jentadueto®), metformin can potentially lower your vitamin B12 levels over time, especially with long-term use and higher doses. If you experience symptoms like extreme tiredness, a sore and red tongue, mouth ulcers, pins and needles, or pale or yellow skin, you should speak to your doctor. Your doctor may check your blood for low vitamin B12 and might recommend a supplement if needed.

Are there any specific concerns for drivers who take linagliptin?

Yes, if you are a driver, you should be particularly careful because poorly controlled diabetes can affect your concentration. It may be advisable to check your blood sugar levels before driving and to carry a snack for longer journeys to help maintain stable blood sugar.

What are the common side-effects of linagliptin?

Linagliptin can cause some side-effects, though they affect fewer than 1 in 100 people. These include cough, nose and throat symptoms, and rash. If any of these become bothersome or continue, you should speak with your doctor or pharmacist for advice.

What should I look out for if my blood sugar levels get too high?

If your blood sugar levels become too high, you might notice symptoms like unusual thirst, needing to pass urine more frequently than usual, and feeling very tired. If you experience these signs, you should let your doctor know, as your treatment may need adjustment.

What if I miss a dose of linagliptin?

If you forget to take a dose of linagliptin, take it as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose entirely. Do not take two doses at once to compensate for the forgotten one.

Can linagliptin be taken with food?

If you are taking the Trajenta® brand of linagliptin (5 mg), you can take the tablet either with or without food. If you are taking the combination tablet Jentadueto® (linagliptin with metformin), it is recommended to take it after you have eaten a meal or with a snack, as this can help reduce the chance of an upset stomach.

Dessa frågor och svar har genererats från informationen i denna artikel.