Nateglinid för diabetes
Starlix
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 30 Aug 2023
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Klinisk författares anmärkning Michael Stewart 08/08/2023: Starlix® tablets were discontinued in the United Kingdom in August 2020. At the time of review there are no licensed injection products containing nateglinide available in the UK. Nateglinide may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Take nateglinide up to 30 minutes before each of your three main meals.
The most common side-effects are feeling shaky, feeling hungry, having a feeling of a pounding heart (palpitations), feeling dizzy (hypoglycaemia) and stomach upset (nausea, diarrhoea, indigestion).
Remember to follow any advice you have been given about your diet.
Överblick
Nateglinide is a medicine for people with type 2 diabetes.
It helps to lower blood sugar by encouraging your pancreas to produce more insulin.
Take one tablet three times daily immediately before or up to 30 minutes before your main meals.
Common side-effects include symptoms of low blood sugar, diarrhoea, and tummy pain.
Tell your doctor if you experience unusually frequent thirst, more frequent urination, or feel very tired.
About nateglinide
Typ av medicin | An antidiabetic medicine |
Används för | Type 2 diabetes mellitus |
Även kallad | Starlix® (discontinued) |
Tillgänglig som | Tabletter |
Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called diabetes (diabetes mellitus).
People with diabetes need treatment to control the amount of glucose in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like nateglinide are given alongside the changes in diet.
Nateglinide lowers blood sugar by encouraging your pancreas to produce more insulin. It starts to work quickly so it is particularly helpful in controlling blood sugar levels straight after a meal. Nateglinide will be prescribed for you alongside another antidiabetic medicine called metformin.
Before taking nateglinide
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking nateglinide it is important that your doctor knows:
If you are under 18 or over 75 years of age.
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your liver works.
If you have a severe illness or infection.
Om du någonsin har haft en allergisk reaktion mot en medicin.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
How to take nateglinide
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about nateglinide tablets and will provide you with a full list of the side-effects which you may experience from taking them.
Take nateglinide exactly as your doctor tells you to. The usual dose is one tablet three times daily, before your main meals (usually breakfast, lunch and dinner). It is best to take the tablet immediately before you eat your meal, but it can be taken up to 30 minutes before a meal. If you miss a meal, do not take a tablet.
You will be prescribed a low dose to begin with. If it becomes necessary, your doctor may increase the number of tablets you need to take each day.
Swallow the tablet with a drink of water. Do not break or crush the tablets.
If you forget to take a dose, do not worry, just take your next dose at the next mealtime. Do not take two doses together to make up for a forgotten dose, and do not take the tablets between meals.
Få ut det mesta av din behandling
It is important that you keep your regular doctor's and clinic appointments. This is so your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your doctor and diabetes clinic.
Your doctor may recommend that you test for sugar (glucose) in your blood or urine regularly to check that your diabetes is being controlled. Your doctor or diabetes nurse will show you how to do this.
Drinking alcohol is not recommended with nateglinide as it can affect the control of your blood sugar.
If you are a driver you should take special care, as your ability to concentrate may be affected if your diabetes is not well controlled. You may be advised to check your blood sugar levels before you travel and to have a snack with you on long journeys.
If you have been given advice by your doctor about changes to your diet, stopping smoking or taking regular exercise, it is important for you to follow the advice you have been given.
Check with your doctor before taking up any new physical exercise, as this will have an effect on your blood sugar levels and you may need to check your blood or urine levels more regularly.
Make sure you know what it feels like if your blood sugar is low. This is known as hypoglycaemia, or a 'hypo'. The first signs of hypoglycaemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy.
If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and that you are taking nateglinide. This is because if you are not able to eat for a time, you will be advised to skip your doses until you are eating normally again.
If you get unusually thirsty, pass urine more frequently, and feel very tired, you should let your doctor know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.
Treatment for diabetes is usually lifelong. Continue to take the tablets unless you are advised otherwise by your doctor.
Can nateglinide cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with nateglinide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common nateglinide side-effects (these affect fewer than 1 in 10 people) | Vad kan jag göra om jag upplever detta? |
Symptoms of hypoglycaemia: feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling of a pounding heart (palpitations), feeling dizzy | Eat something containing sugar, such as a biscuit or a sugary drink (not diet), and follow this up with a snack such as a sandwich. Do not drive and do not use tools or machines until you feel better. Tell your doctor if you notice these symptoms frequently |
Diarrhoea, tummy (abdominal) pain, indigestion, feeling sick (nausea) | Let your doctor know if any of these become severe or troublesome |
Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.
How to store nateglinide
Förvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Viktig information om alla läkemedel
Om du köper några läkemedel, kontrollera alltid med en farmaceut att de är säkra att ta tillsammans med dina andra läkemedel.
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
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Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vanliga frågor
Can I take nateglinide if I am taking other medications?
You should always tell your doctor about any other medicines you are taking, including those you can buy without a prescription, as well as herbal and complementary medicines. This is important because some medicines are not suitable to be taken with nateglinide, or may require extra care.
What should I do if I forget to take my nateglinide dose?
If you forget to take a dose, you should not worry. Just take your next dose at the next mealtime. Do not take two doses together to make up for a forgotten dose, and do not take the tablets between meals.
What are the common symptoms of low blood sugar (hypoglycaemia) and what should I do if I experience them?
The first signs of low blood sugar, also known as a 'hypo', include feeling shaky or anxious, sweating, looking pale, feeling hungry, a pounding heart (palpitations), and feeling dizzy. If you experience these, eat something sugary, like a biscuit or a non-diet sugary drink, and then follow it up with a snack such as a sandwich. Avoid driving or operating machinery until you feel better, and inform your doctor if these symptoms occur frequently.
What should I do if I think my blood sugar is too high?
If you experience unusual thirst, pass urine more frequently, and feel very tired, these could be signs that your blood sugar levels are too high. You should inform your doctor immediately so they can assess your condition and potentially adjust your treatment.
What should I do with expired or unwanted nateglinide tablets?
Do not keep out-of-date or unwanted medicines at home. You should take them to your local pharmacy, which will safely dispose of them for you.
Vidare läsning och referenser
- Manufacturer's PIL, Starlix® 60 mg, 120 mg, 180 mg film-coated tablets; Novartis Pharmaceuticals UK Ltd, The electronic Medicines Compendium. Dated May 2018.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
Om författarenVisa fullständig biografi

Michael Stewart, MRPharmS
Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare
BPharm (Hons), MRPharmS
Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.
Om recensenten

Sid Dajani
Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.
Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.
Next review due: 29 Aug 2026
30 Aug 2023 | Senaste versionen

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