Procyclidine
Kemadrin
Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSLast updated 24 feb 2023
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Procyclidine is used to relieve unwanted side-effects caused by antipsychotic medicines. It may also be used in the early stages of Parkinson's disease.
It is usually prescribed as a three times daily dose, but you may be advised to take it more or less often than this. Take it exactly as your doctor tells you to.
The most common side-effects are a dry mouth, constipation, blurred vision and difficulties passing urine.
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About procyclidine
Typ av medicin | An antimuscarinic medicine |
Används för | Unwanted 'extrapyramidal side-effects' caused by some medicines, Parkinson's disease and Parkinsonism |
Även kallad | Kemadrin® |
Tillgänglig som | Tablets, oral liquid and injection |
Procyclidine is used to relieve unwanted side-effects caused by some antipsychotic medicines. Antipsychotic medicines are prescribed for mental health problems such as schizophrenia. As a side-effect of treatment, antipsychotic medicines can sometimes cause unwanted body movements, some of which may be severe. These movement disorders are often referred to as 'extrapyramidal side-effects' or 'Parkinsonism' and include things like uncontrolled face and body movements, shakiness (tremor), and restlessness. Procyclidine is prescribed to relieve these types of symptoms.
Procyclidine is also used to relieve some of the symptoms of Parkinson's disease, which include movement problems such as stiff muscles, shakiness (tremor) and eye movements, as well as sweating and producing too much saliva.
Before taking procyclidine
Tillbaka till innehållSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking procyclidine it is important that your doctor knows:
Om du är gravid, försöker bli gravid eller ammar.
If you have any problems with the way your liver works, or the way your kidneys work.
If you have any problems with your heart or blood vessels.
If you have prostate problems, or if you have been experiencing difficulty passing urine.
If you have been constipated for more than a week or if you have been told you have an obstruction in your bowel.
If you have a condition which causes raised pressure in your eyes, such as glaucoma.
If you have high blood pressure (hypertension).
Om du har ett tillstånd som orsakar muskelsvaghet, kallat myasthenia gravis.
If you have ever had a mental health problem called psychosis.
Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.
Om du någonsin har haft en allergisk reaktion mot en medicin.
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How to take procyclidine
Tillbaka till innehållBefore you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about procyclidine and a full list of the side-effects which you may experience from taking it.
Take procyclidine exactly as your doctor tells you to. When starting your treatment your doctor will give you a small dose (usually half a tablet or 5 ml liquid medicine three times daily), and then may gradually increase your dose.
Carefully follow the directions your doctor gives to you. Although procyclidine is usually prescribed as a three times daily dose, you may be advised to take it more or less often than this.
It is not important whether you take procyclidine before or after food, although some people find taking it with meals helps prevent feelings of sickness (nausea).
Try to take your doses of procyclidine at the same times of day, each day. This will help you to remember to take your doses regularly.
If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.
Få ut det mesta av din behandling
Tillbaka till innehållFörsök att hålla dina regelbundna möten med din läkare. Detta är så att din läkare kan följa upp din utveckling.
If you buy any medicines, check with a pharmacist that they are safe to take with procyclidine. Some antihistamines and some strong painkillers can interfere with procyclidine and increase the risk of side-effects.
If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking procyclidine.
If you have been taking procyclidine for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually when this is necessary.
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Can procyclidine cause problems?
Tillbaka till innehållAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with procyclidine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common procyclidine side-effects - these affect fewer than 1 in 10 people | Vad kan jag göra om jag upplever detta? |
Torr mun | Försök tugga sockerfritt tuggummi eller suga på sockerfria karameller |
Förstoppning | Try to eat a well-balanced diet and drink several glasses of water each day |
Blurred vision, feeling dizzy | Kör inte och använd inte verktyg eller maskiner förrän du mår bättre |
Difficulty passing urine | If this becomes troublesome, let your doctor know |
Less common procyclidine side-effects - these affect fewer than 1 in 100 people | Vad kan jag göra om jag upplever detta? |
Feeling sick (nausea) or being sick (vomiting) | Stick to simple foods - avoid rich or spicy meals. Try taking procyclidine after meals if you are not already doing so |
A fast heartbeat, skin rash, mood changes, and feeling anxious, confused or forgetful | If any of these become troublesome, let your doctor know |
Om du upplever några andra symtom som du tror kan bero på denna medicin, tala med din läkare eller apotekare.
How to store procyclidine
Tillbaka till innehållFörvara alla läkemedel utom räckhåll och synhåll för barn.
Förvara på en sval, torr plats, borta från direkt värme och ljus.
Viktig information om alla läkemedel
Tillbaka till innehållViktig information om alla läkemedel
Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.
Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.
Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.
Om du har några frågor om denna medicin, fråga din apotekare.
Rapportera biverkningar av ett läkemedel eller vaccin
Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.
Vidare läsning och referenser
- Manufacturer's PIL, Kemadrin® Tablets 5 mg; Aspen Pharma Trading Ltd, The electronic Medicines Compendium. Dated August 2015.
- Mediciner Komplett BNF 89:e Utgåvan; Brittiska Läkarföreningen och Kungliga Farmaceutiska Sällskapet i Storbritannien, London.
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Artikelhistorik
Informationen på denna sida är skriven och granskad av kvalificerade kliniker.
Nästa granskning: 23 aug 2027
24 feb 2023 | Senaste versionen

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