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Treosulfan

Granskad av Sid DajaniSenast uppdaterad av Michael Stewart, MRPharmSSenast uppdaterad 23 Aug 2024

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Klinisk författares anmärkning

Michael Stewart 24/08/2024: Treosulfan 250 mg capsules have been discontinued in the United Kingdom. At the time of review there are no branded or generic tablets or capsules containing treosulfan available in the UK. Treosulfan is still available as a solution for infusion, administered in hospital. The information in this leaflet may still be relevant if you are being treated with treosulfan infusions. Please read the information given to you by your hospital and refer to any manufacturer's information supplied with your medicine.

Treosulfan will be prescribed for you by a specialist doctor.

Please keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please see your doctor straightaway.

Överblick

  • Treosulfan is a chemotherapy medicine used to treat ovarian cancer in women.

  • It works by preventing cancer cells from multiplying.

  • Your doctor will prescribe it, often with other treatments.

  • You must tell your doctor if you are pregnant, breastfeeding, have an infection, or other conditions.

  • Drink plenty of fluid and pass urine frequently during treatment.

  • Treosulfan can lower your resistance to infection, so avoid people with infections.

  • Report a sore throat or high temperature to your doctor immediately.

  • Do not get pregnant during treatment and for six months after.

Denna sammanfattning har automatiskt genererats från artikelns innehåll för att hjälpa läsarna att snabbt förstå huvudpunkterna.

About treosulfan

Typ av medicin

An alkylating chemotherapy medicine

Används för

Cancer of the ovaries

Tillgänglig som

Capsules (discontinued) and injection

Treosulfan is used to treat äggstockscancer in women. In cancer, certain cells in your body grow and multiply too fast. Chemotherapy medicines like treosulfan work by preventing cells from multiplying. This reduces the number of cancer cells made.

Treosulfan may be given alongside other medicines or treatments to help treat your condition.

Before taking treosulfan

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking treosulfan it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have an infection or feel unwell.

  • If you have a rare inherited blood condition called porphyria.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

How to take treosulfan

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet. These will give you more information about treosulfan and will provide you with a full list of the side-effects which you may experience from having treatment.

  • Treosulfan will be prescribed for you by a specialist doctor who is experienced in treating your condition.

  • While you are having treosulfan treatment, it is important that you drink plenty of fluid and that you pass urine frequently. Drinking lots of water and other fluids will help prevent a serious type of cystitis sometimes caused by this medicine.

Få ut det mesta av din behandling

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with treosulfan.

  • While you are having treosulfan and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Treosulfan lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

  • It is important that you do not get pregnant while you are having treosulfan. If appropriate, please discuss with your doctor which types of contraception are suitable for you and your partner.

Can treosulfan cause problems?

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking treosulfan you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment, although not everyone experiences these. The table below contains some of the side-effects associated with treosulfan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Very common treosulfan side-effects (these affect more than 1 in 10 women)

Vad kan jag göra om jag upplever detta?

A high temperature (fever), or symptoms of an infection

Let your doctor know about this straightaway

Feeling sick (nausea) or being sick (vomiting)

Stick to simple meals - avoid rich or spicy food. If this becomes troublesome, let your doctor know, as you can be prescribed an anti-sickness medicine

Some loss of hair; a bronze skin colouration

Discuss these with your doctor if you are concerned

Rare treosulfan side-effects

Vad kan jag göra om jag upplever detta?

A burning feeling as you pass urine, blood in your urine

Continue to drink plenty of water and try to pass urine frequently. If you notice blood in your urine, please let your doctor know straightaway

Feeling short of breath

Let your doctor know about this straightaway. It could be a sign of a rare but serious lung condition

Om du upplever några andra symtom som du tror kan bero på kapslarna, vänligen tala med din läkare eller apotekare för vidare råd.

How to store treosulfan

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card webbplats.

symptomkontroll

Osäker på att blanda mediciner?

Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

What happens if I miss an appointment during my treosulfan treatment?

It's very important to keep all your regular appointments with your doctor or hospital while on treosulfan. This allows your doctor to monitor your progress and conduct necessary blood tests and check-ups. If you miss an appointment, you should contact your clinic as soon as possible to reschedule.

Are there any specific foods or drinks I should avoid while on treosulfan?

The article mentions that if you experience feeling sick or being sick, you should stick to simple meals and avoid rich or spicy food. It does not mention any other specific food or drink restrictions.

How can I tell if a high temperature or feeling unwell is a side effect of treosulfan or a sign of infection?

A high temperature (fever) or symptoms of an infection are listed as very common side-effects of treosulfan. Since treosulfan lowers your body's resistance and increases the risk of infection, it's crucial to let your doctor know straightaway if you experience these symptoms, so they can determine the cause and provide appropriate treatment.

Can treosulfan make my skin sensitive to the sun?

The article mentions a bronze skin colouration as a possible side effect of treosulfan. However, it does not specifically state that treosulfan makes your skin more sensitive to the sun. If you are concerned about this side effect, you should discuss it with your doctor.

What should I do if I think I've taken too much treosulfan?

If you suspect that you or someone else might have taken an overdose of treosulfan, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.

Dessa frågor och svar har genererats från informationen i denna artikel.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

Artikeln finns också på Engelska, Tyska, Spanska, Franska, Italienska, Portugisiska, Hindi, Hebreiska, Arabiska, och Svenska.

  • Next review due: 25 Aug 2027
  • 23 Aug 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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