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Treosulfan

Clinical author's note

Michael Stewart 24/08/2024: Treosulfan 250 mg capsules have been discontinued in the United Kingdom. At the time of review there are no branded or generic tablets or capsules containing treosulfan available in the UK. Treosulfan is still available as a solution for infusion, administered in hospital. The information in this leaflet may still be relevant if you are being treated with treosulfan infusions. Please read the information given to you by your hospital and refer to any manufacturer's information supplied with your medicine.

Treosulfan will be prescribed for you by a specialist doctor.

Please keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please see your doctor straightaway.

Fortsätt läsa nedan

About treosulfan

Typ av medicin

An alkylating chemotherapy medicine

Används för

Cancer of the ovaries

Tillgänglig som

Capsules (discontinued) and injection

Treosulfan is used to treat äggstockscancer in women. In cancer, certain cells in your body grow and multiply too fast. Chemotherapy medicines like treosulfan work by preventing cells from multiplying. This reduces the number of cancer cells made.

Treosulfan may be given alongside other medicines or treatments to help treat your condition.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking treosulfan it is important that your doctor knows:

  • Om du är gravid eller ammar.

  • If you have an infection or feel unwell.

  • If you have a rare inherited blood condition called porphyria.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

Fortsätt läsa nedan

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet. These will give you more information about treosulfan and will provide you with a full list of the side-effects which you may experience from having treatment.

  • Treosulfan will be prescribed for you by a specialist doctor who is experienced in treating your condition.

  • While you are having treosulfan treatment, it is important that you drink plenty of fluid and that you pass urine frequently. Drinking lots of water and other fluids will help prevent a serious type of cystitis sometimes caused by this medicine.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with treosulfan.

  • While you are having treosulfan and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Treosulfan lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

  • It is important that you do not get pregnant while you are having treosulfan. If appropriate, please discuss with your doctor which types of contraception are suitable for you and your partner.

Fortsätt läsa nedan

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking treosulfan you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment, although not everyone experiences these. The table below contains some of the side-effects associated with treosulfan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Very common treosulfan side-effects (these affect more than 1 in 10 women)

Vad kan jag göra om jag upplever detta?

A high temperature (fever), or symptoms of an infection

Let your doctor know about this straightaway

Feeling sick (nausea) or being sick (vomiting)

Stick to simple meals - avoid rich or spicy food. If this becomes troublesome, let your doctor know, as you can be prescribed an anti-sickness medicine

Some loss of hair; a bronze skin colouration

Discuss these with your doctor if you are concerned

Rare treosulfan side-effects

Vad kan jag göra om jag upplever detta?

A burning feeling as you pass urine, blood in your urine

Continue to drink plenty of water and try to pass urine frequently. If you notice blood in your urine, please let your doctor know straightaway

Feeling short of breath

Let your doctor know about this straightaway. It could be a sign of a rare but serious lung condition

Om du upplever några andra symtom som du tror kan bero på kapslarna, vänligen tala med din läkare eller apotekare för vidare råd.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Om du ska genomgå en operation eller tandbehandling, informera den som utför behandlingen om vilka mediciner du tar.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vidare läsning och referenser

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 25 Aug 2027
  • 23 Aug 2024 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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