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Toremifen för bröstcancer

Fareston

Take one tablet of toremifene each day.

You can take the tablet before or after food.

The most common side-effects are hot flushes and sweating.

Överblick

  • Toremifene is a hormone treatment for metastatic breast cancer.

  • It works by blocking receptors that oestrogen needs to attach to cancer cells.

  • Take one 60 mg tablet daily, at the same time each day.

  • Hot flushes and sweating are very common side-effects.

  • Contact a doctor if you experience pain or swelling in a leg, or shortness of breath.

About toremifene

Typ av medicin

An anti-oestrogen hormone antagonist

Används för

Metastatic breast cancer

Även kallad

Fareston®

Tillgänglig som

Tabletter

Treatment options for women with bröstcancer include surgery, radiotherapy, chemotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Toremifene is a hormone treatment.

Some breast cancers need the female hormone oestrogen to grow. The cells of these cancers have receptors on their surface that oestrogen can attach to and are called 'hormone receptor-positive' cancers. Toremifene works by blocking the receptors and this prevents oestrogen from reaching the cancer cells. This helps to control the cancer. It is prescribed for women with breast cancer where the cancer cells have also spread to another part of the body, such as the lungs, liver or bones. This sort of breast cancer is referred to as metastatic breast cancer, or secondary breast cancer.

Before taking toremifene

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking toremifene it is important that your doctor knows:

  • If you are still having menstrual periods. If so, you should not take toremifene.

  • If you have had a stroke, a blood clot in your lungs, or deep venous thrombosis (DVT).

  • If you have a heart condition, or a heart rate or rhythm problem.

  • If you have been told the lining of your womb has become thickened, a condition called endometrial hyperplasia.

  • If you have problems with the way your liver works.

  • Om du har en sällsynt ärftlig blodsjukdom som kallas porfyri.

  • Om du tar några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

How to take toremifene

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about toremifene and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take one 60 mg tablet each day, exactly as your doctor tells you to.

  • You may take toremifene at whatever time of day you find easiest to remember, but try to take your doses at the same time of day, each day. This will help you to remember to take your doses regularly.

  • You can take toremifene tablets before or after meals.

  • If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Få ut det mesta av din behandling

  • Try to keep your regular appointments with your doctor or clinic. This is so your doctor can check on your progress. This is particularly important if you also have bone cancer, as you will need to have regular blood tests when you start this treatment.

  • If you are having an operation, tell the person carrying out the treatment that you are taking toremifene.

  • If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines.

Can toremifene cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with toremifene. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common toremifene side-effects (these affect more than 1 in 10 women)


Vad kan jag göra om jag upplever detta?

Hot flushes and sweating

Try to keep cool by wearing light, airy clothes

Common toremifene side-effects (these affect fewer than 1 in 10 women)

Vad kan jag göra om jag upplever detta?

Feeling sick (nausea) or being sick (vomiting)

Stick to simple meals and avoid rich or spicy foods

Feeling dizzy or tired

Kör inte och använd inte verktyg eller maskiner när du är påverkad

Vaginal bleeding or discharge

Let your doctor know straightaway so the cause can be investigated. Your doctor will want to check to see if there are any changes that could cause concern in the lining of your womb

Itchy skin rash, swollen feet or ankles, feeling depressed

If any of these become troublesome, speak with your doctor for advice

Important: Some women taking toremifene have experienced a problem with a blood clot in the legs or lungs. Although this occurs less commonly than the side-effects mentioned above, if you experience any pain or swelling in a leg, or have any shortness of breath, please contact a doctor for advice as soon as possible.

Om du upplever några andra symtom som du tror kan bero på tabletterna, tala med din läkare eller apotekare för vidare råd.

How to store toremifene

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

Viktig information om alla läkemedel

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

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Rapportera misstänkta biverkningar av läkemedel, vacciner, e-cigaretter, medicintekniska händelser, defekta eller förfalskade (falska) produkter till Läkemedelsverket för att säkerställa säker och effektiv användning.

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Kontrollera möjliga interaktioner mellan läkemedel, kosttillskott och livsmedel innan du tar dem tillsammans.

Vanliga frågor

Can I take toremifene if I'm still having menstrual periods?

No, if you are still having menstrual periods, you should not take toremifene. It is important to inform your doctor about your menstrual status before starting this medication.

Why would my doctor want to check on my progress, especially if I have bone cancer?

Regular appointments with your doctor or clinic are important to monitor your progress. If you have bone cancer, it's particularly crucial because you will need to have regular blood tests when you start this treatment to ensure it is working effectively and safely.

What should I do if I experience vaginal bleeding or discharge while taking toremifene?

If you experience vaginal bleeding or discharge, you should let your doctor know straight away. This is important so the cause can be investigated. Your doctor will likely want to check for any changes in the lining of your womb that could be a concern.

Are there any specific symptoms I should watch out for that indicate a serious problem, even if they are rare?

Yes, although less common than other side effects, some women taking toremifene have experienced blood clots in the legs or lungs. If you experience any pain or swelling in a leg, or have any shortness of breath, you should contact a doctor for advice as soon as possible.

How should I dispose of any leftover or expired toremifene tablets?

You should not keep out-of-date or unwanted medicines. Take them to your local pharmacy, which will dispose of them for you safely.

Vidare läsning och referenser

Om författarenVisa fullständig biografi

Författarbild

Michael Stewart, MRPharmS

Ansvarig för granskning av medicinbroschyrer – Konsult, Apotekare

BPharm (Hons), MRPharmS

Michael är en apotekare som arbetar i Midlands och South Yorkshire med mer än 20 års erfarenhet av att ge råd om läkemedel och medicinska tillstånd. Han har en stark bakgrund inom vårdutbildning och har producerat och levererat utbildningskurser för apoteksteam och personal inom vårdboenden, inklusive sjuksköterskor. Han har också bidragit till apoteksrådgivande styrelser för hantering av mindre allvarliga tillstånd i samhället.

Om recensenten

Författarbild

Sid Dajani

Sultan Dajani tog examen vid London School of Pharmacy 1994 och blev den yngsta valda medlemmen i Royal Pharmaceutical Society-rådet sedan dess grundande 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 26 Nov 2026
  • 27 nov 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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