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Erlotinib tablets

Tarceva

Erlotinib is given for the treatment of lung cancer, or for the treatment of cancer of the pancreas. It is taken once a day.

You will need to have regular check-ups so it is important that you keep your appointments with your doctor and/or hospital.

Contact your doctor straightaway if you develop any of the following: severe or persistent diarrhoea, eye irritation, or sudden difficulties with your breathing (especially if you also have a cough and/or a high temperature).

At a glance

  • Erlotinib is a chemotherapy medicine for lung cancer and pancreatic cancer.

  • Take tablets once daily on an empty stomach, either one hour before food or two hours after.

  • Smoking can make erlotinib less effective.

  • Do not get pregnant or father a child while taking this medicine.

  • If you develop a dry cough, high temperature, or sudden breathing problems, tell your doctor straight away.

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About erlotinib

Typ av medicin

A tyrosine kinase inhibitor chemotherapy medicine

Används för

Lung cancer, and cancer of the pancreas

Även kallad

Tarceva®

Tillgänglig som

Tabletter

Erlotinib is a medicine which is given for the treatment of lung cancer och pancreatic cancer. You may be prescribed it alongside other medicines for cancer.

In cancer, certain cells in the body grow and multiply in a way that is 'out of control'. Chemotherapy (anti-cancer) medicines work by inhibiting the way the cells grow and increase in number. Erlotinib works by blocking chemical messengers which send signals to cells to grow. This in turn stops the cancer cells from growing and increasing in number.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking erlotinib it is important that your doctor knows:

  • If you have an infection or feel particularly unwell.

  • If you have any problems with the way your liver works or with the way your kidneys work.

  • Om du är gravid eller ammar.

  • Om du tar eller använder några andra läkemedel. Detta inkluderar alla läkemedel du tar som finns att köpa utan recept, samt växtbaserade och komplementära läkemedel.

  • Om du någonsin har haft en allergisk reaktion mot en medicin.

Fortsätt läsa nedan

  • Before you start the treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside the pack of tablets. These will give you more information about erlotinib and will provide a full list of the side-effects which you may experience from taking it.

  • Erlotinib will be prescribed for you by a specialist doctor who is experienced in treating your condition. Erlotinib is taken once daily. There are several strengths of tablet available - your doctor will tell you what strength of tablet is right for you. It is important that you take the tablets exactly as you are told to. The directions for taking the tablets will be printed on the label of the pack to remind you, but if you are still unsure about what to do, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.

  • Take erlotinib at the same time of day each day, as this will help you to remember to take your doses regularly. You should take the tablets when your stomach is empty, which means taking them one hour before any food, or waiting until two hours afterwards.

  • If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, take the dose that is due but do not take the forgotten dose. Let your doctor know that you have missed a dose.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular check-ups during treatment. If at any time you develop a dry cough, a high temperature, or a sudden problem with your breathing, you must let your doctor know about it straightaway so that it can be investigated.

  • Smoking can reduce the effectiveness of the treatment, as it lowers the amount of erlotinib in your body. If you are a smoker you should try to quit, but make sure you tell your doctor about stopping.

  • If you buy or take any other medicines, check with a pharmacist that they are suitable to take alongside erlotinib. You should not take antacids or other preparations for indigestion, as these can reduce the effectiveness of erlotinib.

  • If you are having an operation or dental treatment, always tell the person carrying out the treatment which medicines you are taking.

  • It is important that you do not get pregnant or father a child while you are taking erlotinib. If relevant, make sure you discuss with your doctor which types of contraception are suitable for you and your partner.

Fortsätt läsa nedan

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with erlotinib. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common erlotinib side-effects (these affect more than 1 in 10 people)


Vad kan jag göra om jag upplever detta?

Diarré

Drink plenty of water. If this continues or becomes severe, you should let your doctor know

Feeling sick (nausea) or being sick (vomiting), abdominal discomfort, indigestion (reflux), wind (flatulence)

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Känner dig trött

Do not drive and do not use tools or machines unless you feel well enough

Problems with eyesight, cough, sudden problems with breathing, high temperature, infections

Speak with your doctor

as soon as possible

Weight loss, sore mouth, itchy skin rash, mood changes, headache, loss of hair, tingling or numbness in your hands or feet

If any become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to the tablets, ask your doctor or pharmacist for advice.

  • Förvara alla läkemedel utom räckhåll och synhåll för barn.

  • Förvara på en sval, torr plats, borta från direkt värme och ljus.

  • Please return any unused or unwanted tablets to your clinic or pharmacy to destroy.

Viktig information om alla läkemedel

Ta aldrig mer än den föreskrivna dosen. Om du misstänker att du eller någon annan kan ha tagit en överdos av denna medicin, gå till akutmottagningen på ditt lokala sjukhus. Ta med behållaren, även om den är tom.

Denna medicin är för dig. Ge den aldrig till andra människor även om deras tillstånd verkar vara detsamma som ditt.

Behåll inte föråldrade eller oönskade mediciner. Ta dem till ditt lokala apotek som kommer att ta hand om dem åt dig.

Om du har några frågor om denna medicin, fråga din apotekare.

Rapportera biverkningar av ett läkemedel eller vaccin

Om du upplever biverkningar kan du rapportera dem online via Yellow Card website.

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Vanliga frågor

Can erlotinib be used for other types of cancer besides lung and pancreatic cancer?

Erlotinib is specifically mentioned as being used for lung cancer and cancer of the pancreas. The article does not indicate its use for other cancer types.

How does erlotinib specifically target cancer cells without harming healthy cells as much as traditional chemotherapy?

Erlotinib works by blocking specific chemical messengers that send signals to cancer cells telling them to grow. By interrupting these signals, it stops the cancer cells from growing and increasing in number.

Why is it important to take erlotinib on an empty stomach?

The instructions for taking erlotinib state that you should take the tablets when your stomach is empty. This means taking them one hour before any food, or waiting until two hours after eating. This specific timing is likely to ensure the medicine is absorbed effectively into your body.

Is it safe to take paracetamol or ibuprofen for pain while on erlotinib?

The article advises checking with a pharmacist if you buy or take any other medicines. It specifically warns against taking antacids or other preparations for indigestion, as they can reduce erlotinib's effectiveness. For specific pain relief like paracetamol or ibuprofen, it's best to consult your pharmacist.

What should I do if I accidentally take two doses of erlotinib?

The article states never to take more than the prescribed dose. If you suspect you or someone else might have taken an overdose, you should go to the accident and emergency department of your local hospital and take the medicine container with you.

How long will I need to be on erlotinib treatment?

The article does not specify the duration of treatment with erlotinib. It mentions that you will have regular check-ups with your doctor or hospital to monitor your progress, suggesting that the treatment length is determined by your specialist doctor.

Are there any specific foods or drinks I should avoid while taking erlotinib?

While the article advises taking erlotinib on an empty stomach and to stick to simple meals for gastrointestinal side effects, it does not list specific foods or drinks to avoid. However, it does warn against taking antacids or other preparations for indigestion.

Can I share my erlotinib tablets with someone else if they have similar symptoms?

No, you must never give your medicine to other people, even if their condition appears to be the same as yours. This medicine is specifically prescribed for you.

Vidare läsning och referenser

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Artikelhistorik

Informationen på denna sida är skriven och granskad av kvalificerade kliniker.

  • Next review due: 18 Jun 2026
  • 19 Jun 2023 | Senaste versionen

    Senast uppdaterad av

    Michael Stewart, MRPharmS

    Granskad av

    Sid Dajani
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